Influence of chlordecone and mirex exposure on benzo[a]pyrene metabolism of rat-liver microsomes

References

• BAKER, R. C., COONS, L. B., MAILMAN, R. B., and HODGSON, E., 1972, Induction of mixed-function oxidase by the insecticide mirex. Environmental Research, 5,418–424.
   PubMed Web of Science ®Google Scholar
• BENTLEY, P., SCHMASSMANN, H., Sims, P., and DESCH, F., 1976, Epoxides derived from various polycyclic hydrocarbons as substrates of homogeneous and microsome-bound epoxide hydratase. European Journal of Biochemistry, 69, 97–103.
   PubMedGoogle Scholar
• BULGER, W. H., MUCITELLI, R. M., and KUPFER, D., 1979, Studies on the estrogenic activity of chlordecone (Kepone) in the rat: effects on uterine estrogen receptor. Molecular Pharmacology, 15, 515–524.
   PubMed Web of Science ®Google Scholar
• CARVER, R. A., BoasErn, A. P., and KAMPS, L. R., 1978, Gas-liquid chromatographic determination of Kepone residues in finfish, shellfish and crustaceans. Journal of the Association of Official Analytical Chemists (Washington), 61, 877–883.
   PubMedGoogle Scholar
• CIRRSHALL, N. H., LARSEN, I. L., and NICHOLS, M. M., 1981, Man-made radionuclides confirm rapid burial of Kepone in James River (Virginia, USA) sediments. Science, 213, 440–442.
   PubMedGoogle Scholar
• DANSETTE, P. M., DuBois, G. C., and JERINA, D. M., 1979, Continuous fluorometric assay of epoxide hydrase activity. Analytical Biochemistry 97, 340–345.
   PubMedGoogle Scholar
• DEHEN, W., TOMAGAS, R., and Roos, J., 1973, A modified method for the assay of benzo[a]pyrene hydroxylase. Analytical Biochemistry, 53, 373–383.
   PubMedGoogle Scholar
• EBEL, R. E., 1980, In vitro effects of chlordecone (Kepone) on hepatic microsomal cytochrome P-450. Pesticide Biochemistry and Physiology, 14, 221–226.
   Google Scholar
• EBEL, R. E., 1982, Alterations in microsomal cytochrome P-450 catalyzed reactions as a function of chlordecone (Kepone) induction. Pesticide Biochemistry and Physiology, 18, 113–121.
   Google Scholar
• EBEL, R. E., 1984, Hepatic microsomal p-nitroanisole O-demethylase: effects of chlordecone or mires induction in male or female rats. Biochemical Pharmacology, 33, 559–564.
   PubMed Web of Science ®Google Scholar
• EBEL, R. E., O'KEEFFE, D. H., and PETERSON, J. A., 1977, Studies of the unique nature of the cytochrome P-450 active site. I. Electron spin resonance spectroscopy as a probe of the hemin iron. Influence of buffer composition, alcohols, and nitrogenous ligands. Archives of Biochemistry and Biophysics, 183, 317–327.
   Google Scholar
• EGLE, J. L., FERNANDEZ, S. B., GUZELIAN., P. S., and BORZELLACA, J. F., 1978, Distribution and excretion of chlordecone (Kepone) in the rat. Drug Metabolism and Disposition, 6, 91–95.
   Google Scholar
• EROSCHENKO, V. P., 1981, Estrogenic activity of the insecticide chlordecone in the reproductive tract of birds and mammals. Journal of Toxicology and Environmental Health, 8, 731–742.
   PubMed Web of Science ®Google Scholar
• FLEISCHER, S., and KERVINA, S., 1974, Subcellular fractionation of rat liver. Methods in Enzymology, 21, 6–93.
   Google Scholar
• FRANCIS, B. M., and METCALFE, R. L., 1984, Evaluation of mirex, photomirex, and chlordecone in the terrestrial aquatic laboratory model ecosystem. Enviromental Health Perspectives, 54, 341–346.
   PubMedGoogle Scholar
• GAINES, T. B., and KIMBROUGH, R. D., 1970, Oral toxicity of mirex in adult rat and suckling rats and notes on the ultrastructure of liver. Archives of Environmental Health, 21, 7–14.
   PubMed Web of Science ®Google Scholar
• GELBOIN, H. V., 1980, Benzo[a]pyrene metabolism, activation, and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes. Physiological Reviews, 60, 1107–1166.
   PubMed Web of Science ®Google Scholar
• GUENGERICH, F. P., DANNAN, G. A., WRIGHT, S. T., MARTIN, M. V., and KAMINSKY, L. S., 1982, Purification and characterization of liver microsomal cytochromes P-450; electrophoretic, spec-tral, catalytic, and immunochemical properties of eight isozymes isolated from rats treated with phenobarbital or fl-naphthoflavone. Biochemistry, 21, 6019–6030,
   PubMed Web of Science ®Google Scholar
• GUZELIAN, P. S., 1982, Comparative toxicology of chlordecone (Kepone) in humans and experimental animals. Annual Reviewed Pharmacology and Toxicology, 22, 89–113.
   PubMed Web of Science ®Google Scholar
• GUZELIAN, P. S., VRANIAN, G., Bon.Arg, J. J., COHN, W. J., and BLANKE, R. V., 1980, Liver structure and function in patients poisoned with chlordecone (Kepone). Gastroenterology, 78, 206–213.
   Google Scholar
• Ho, I. K., Fujimoto, K., HUANG, T. P., and CHANG-TSUI, H., 1981, Neurochemical evaluation of chlordecone toxicology in the mouse. Journal of Toxicology and Environmental Health, 8,701–706.
   Google Scholar
• HOLDER, G. M., YAGI, H., JERINA, D. M., LEVIN, W., Lu, A. Y. H., and CONNEY, A. H., 1974, Effects of inducers and epoxide hydrase on the metabolism of benzorajpyrene by liver microsomes and a reconstituted system: analysis by high pressure liquid chromatography. Proceedings of the National Academy of Sciences of the United States of America, 71,4356–4360.
   PubMed Web of Science ®Google Scholar
• HOLDER, G. M., YAGI, H., JERINA, D. M., LEVIN, W., Lu, A. Y. H., and CONNEY, A. H., 1975a, Metabolism of benzo[a]pyrene. Effect of substrate concentration and 3-methylcholanthrene pretreatment on hepatic metabolism by microsomes from rats and mice. Archives of Biochemistry and Biophysics, 170,557–566.
   PubMed Web of Science ®Google Scholar
• HOLDER, G. M., YAGI, H., LEVIN, W., Lu, A. Y. H., and JERIN A., 1975b, Metabolism of henzoialpyrene III. An evaluation of the fluorescence assay. Biochemical and Biophysical Research Communications, 65, 1363–1370.
   PubMed Web of Science ®Google Scholar
• KAISER, K. E., 1974, Mirex: an unrecognized contaminant of fishes from Lake Ontario. Science, 185, 523–525.
   PubMed Web of Science ®Google Scholar
• KAMINSKY, L. S., PIPER, L. J., MCMARTIN, D. N., and FASCO, M. J., 1978, Induction of hepatic microsomal P-450 by mirex and kepone. Toxicology and Applied Pharmacology, 43, 327–338.
   PubMed Web of Science ®Google Scholar
• LEVIN, W., WOOD, A., CHANG, R., RYAN, D., THOMAS, P., YAGI, H., THAKKER, D., VYAS, K., BOYD, C., CHU, S., CONNEY, A., and JERINA, D., 1982, Oxidative metabolism of polycyclic aromatic hydrocarbons to ultimate carcinogens. Drug Metabolism Reviews, 13, 555–580.
   PubMed Web of Science ®Google Scholar
• Lu, A. Y. H., JERINA, D. M., and LEVIN, W., 1977, Liver microsomal epoxide hydrase. Hydration of alkene and arene oxides by membrane-bound and purified enzymes. Journal of Biological Chemistry, 252,3715 3723.
   Google Scholar
• LOWRY, O.II., RosEnuot ul 1, N. J., FARE, A. L., and RANDALL, R. J., 1951, Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry, 193,265–275.
   Google Scholar
• MEHENDALE, H., FISHBEIN, L., FIELDS, M., and MATTHEWS, H., 1972, Fate of mirex '4C in the rat and plants. Bulletin of Environmental Contamination and Toxicology, 8, 200–207.
   PubMed Web of Science ®Google Scholar
• MEHENDALE, H., TAKANAK A., DESA1AH, D., and Ho, I. K., 1977, Induction of hepatic mixed-function oxidases in the male rat. Life Sciences, 20, 991–998.
   Google Scholar
• DESCH, F., and GUENTHNER, T. M., 1981, Microsomal epoxide hydrolase and its role in polycyclic aromatic hydrocarbon biotransformation. In Polycyclic Aromatic Hydrocarbons and Cancer, Vol. 3, (New York: Academic Press), pp. 183–212.
   Google Scholar
• OMURA, T., and SATO, R., 1964, The carbon monoxide binding pigment of liver microsomes. I. Evidence of its hemoprotein nature. Journal of Biological Chemistry, 239, 2370–2378.
   PubMed Web of Science ®Google Scholar
• REUBER, M. D., 1978, Carcinogenicity of kepone. Journal of Toxicology and Environmental Health, 8, 895–914.
   Google Scholar
• SOINE, P. J., BLANKE, R. V., GUZELIAN, P. S., and SCHWARTZ, C., 1982, Preferential binding of chlordecone to the protein and high density lipoprotein fractions of plasma from humans and other species. Journal of Toxicology and Environmental Health, 9, 107–118,
   PubMed Web of Science ®Google Scholar
• SOINE, P. J., BLANKE, R. V., and SCHWARTZ, C. C., 1984, Isolation of chlordecone binding proteins from pig liver cytosol. Journal of Toxicology and Environmental Health, 14, 305–317.
   PubMed Web of Science ®Google Scholar
• THAKKER, D. R., YAGI, H., LEVIN, W., WOOD, A. W., CONNEY, A. H., and JERINA, D. M., 1985, Polycyclic aromatic hydrocarbons: metabolic activation to ultimate carcinogens. In Bioactivation of Foreign Compounds, edited by M. W. Anders (New York: Academic Press), pp. 177–242.
   Google Scholar
• VAN CANTFORT, J., DEGRAEVE, J., and GIELEN, J., 1977, Radioactive assay for aryl hydrocarbon hydroxylase. Improved method and biological importance. Biochemical and Biophysical Research Communications, 79, 505–512.
   PubMedGoogle Scholar
• VEITH, G. D., DEFoE, D. L., and BERGSTEDT, B. V., 1979, Measuring and estimating the bioconcentration factors in fish. Journal of the Fisheries Research Board of Canada, 36, 1040.
   Web of Science ®Google Scholar
• WALZ, F. G., VI.ASUK, G. P. and STEGGLES, A. W., 1983, Species differences in cytochrome P-450 and epoxide hydrolase: comparisons of xenobiotic-induced hepatic microsomal polypeptides in hamsters and rats. Biochemistry, 22, 1547–1556.
   Google Scholar
• WATERS, E. M., HUFF, J. E., and GERSTNER, H. B., 1977, Mirex: an overview. Environmental Research, 14, 212–222.
   PubMed Web of Science ®Google Scholar
• WIEBEL, F. J., LEUTZ, J. C., DIAMOND, L., and GELBOIN, H. V., 1971, Aryl hydrocarbon (benzo[a]pyrene) hydroxylase in microsomes from rat livers: differential inhibition and stimulation by benzoflavone and organic solvents. Archives of Biochemistry and Biophysics, 144, 78–86.
   PubMed Web of Science ®Google Scholar