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Xenobiotica
the fate of foreign compounds in biological systems
Volume 18, 1988 - Issue 12
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Original Article

Is the Nephrotoxicity of (R)-3-Chlorolactate in the Rat Caused by 3-Chloropyruvate?

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Pages 1389-1399 | Received 05 Jan 1988, Accepted 10 Jul 1988, Published online: 30 Sep 2009

References

  • Baer E. Phosphoryl‐enolpyruvic acid. Biochemical Preparations 1952; 2: 25–30
  • Bergmeyer H. U., Gawehn K., Grassl M. Enzymes as biochemical reagents; malate dehydrogenase. Methods of Enzymatic Analysis2nd edn., H. U. Bergmeyer. Academic Press, New York 1974; Vol. 1: 485–486
  • Blank I., Mager J., Bergmann E. D. Studies of organic fluorine compounds. Part IV. Synthesis of esters of fluoro‐oxaloacetic and of fluoropyruvic acid. Journal of the Chemical Society 1955; 2190–2193
  • Brown J. P., Perham. Selective inactivation of the transacylase components of the 2‐oxo‐acid dehydrogenase multienzyme complex of Escherichia coli. Biochemical Journal 1976; 155: 419–427
  • Busch H., Nair P. V., Frank M., Martin W. R. Comparative pharmacological effects of a number of β‐halogenated pyruvic acids. Journal of Pharmacology and Experimental Therapeutics 1958; 123: 48–53
  • Bustamante E., Soper J. W., Pedersen P. L. A high‐yield preparative method for isolation of rat liver mitochondria. Analytical Biochemistry 1977; 80: 401–408
  • Coakley W. T., James C. J. A simple linear transform for the Folin‐Lowry protein calibration curve to 1.0mg/ml. Analytical Biochemistry 1978; 85: 90–97
  • Cromartie T. H., Walsh C. T. Rat kidney L‐α‐hydroxy acid oxidase: Isolation of enzyme with one flavine coenzyme per two subunits. Biochemistry 1975a; 14: 2588–2596
  • Cromartie T. H., Walsh C. T. Mechanistic studies on the rat kidney flavoenzyme L‐α‐hydroxy acid oxidase. Biochemistry 1975b; 14: 3482–3490
  • Dawson A. G. Preparation and some properties of a suspension of fragmented tubules from rat kidney. Biochemical Journal 1972; 130: 525–532
  • Dawson A. G. Contribution of pH‐sensitive metabolic process to pH homeostasis in isolated rat kidney tubules. Biochimica et Biophysica Acta 1977; 499: 85–98
  • Doedens D., Ashmore J. Inhibition of pyruvate carboxylase by chloropyruvic acid and related compounds. Biochemical Pharmacology 1972; 21: 1745–1751
  • Fakhouri G., Jones A. R. Epi‐chlorohydrin: metabolism and toxicity in the rat. Australian Journal of Pharmaceutical Sciences 1979; 8: 11–14
  • Franke W., Holz E. Zur kenntnis der spezifität von dehydrogenasen, IV. Über das verhalten halogen‐, hydroxyl‐und amino‐substituierter milchsäuren gegenüber lactatdehydrogenase aus muskel. Zeitschrift für physiologische Chemie 1959; 314: 22–27
  • Heilbron I., Cook A. H., Bunbury H. M., Hey D. H. Dictionary of Organic Compounds4th edn., J. R. A. Pollock, R. Stevens. Eyre and Spottiswoode, London 1965; 2829
  • Hirschbein B. L., Whitesides G. M. Laboratory scale enzymatic/chemical synthesis of D‐ and L‐β‐chlorolactic acid and D‐ and L‐potassium glycidate. Journal of the American Chemical Society 1982; 104: 4458–4460
  • Johnson M. K. Metabolism of chloroethanol in the rat. Biochemical Pharmacology 1967; 16: 185–199
  • Jones A. R. Antifertility actions of α‐chlorohydrin in the male. Australian Journal of Biological Sciences 1983; 36: 333–350
  • Jones A. R., Fakhouri G. Epoxides as obligatory intermediates in the metabolism of α‐halohydrins. Xenobiotica 1979; 9: 595–599
  • Jones A. R., Gibson J. 1,2‐Dichloropropane: metabolism and fate in the rat. Xenobiotica 1980; 10: 835–846
  • Jones A. R., Wells G. The comparative metabolism of 2‐bromoethanol and ethylene oxide in the rat. Xenobiotica 1981; 11: 763–770
  • Jones A. R., Milton D. H., Murcott C. The oxidative metabolism of α‐chlorohydrin in the male rat and the formation of spermatocoeles. Xenobiotica 1978; 8: 573–582
  • Jones A. R., Fakhouri G., Gadiel P. The metabolism of the soil fumigant 1,2‐dibromo‐ 3‐chloropropane in the rat. Experientia 1979a; 35: 1432–1434
  • Jones A. R., Gadiel P., Murcott C. The renal toxicity of the rodenticide α‐chlorohydrin in the rat. Naturwissenschaften 1979b; 66: 425
  • Johes A. R., Mashford P. M., Murcott C. The metabolism of 3‐amino‐1‐chloropropan‐ 2‐ol in relation to its antifertility activity in male rats. Xenobiotica 1979c; 9: 253–261
  • Jones A. R., Porter K., Stevenson D. The renal toxicity of some halogenated derivatives of propane in the rat. Naturwissenschaften 1981; 68: 98
  • Koelsch C. F. A sulfur analog of glyceric acid. Beta‐thioglyceric acid. Journal of the American Chemical Society 1930; 52: 1105–1108
  • Krebs H. A., Bennett D. A. H., de Gasquet P., Gascoyne T., Yoshida T. Renal gluconeogenesis. The effect of diet on the gluconeogenic capacity of rat‐kidney‐cortex slices. Biochemical Journal 1963; 86: 22–27
  • Lowry O. H., Rosebrough N. J., Farr A. L., Randall R. J. Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry 1951; 193: 265–275
  • Merz J. H., Waters W. A. Some oxidations involving the free hydroxyl radical. Journal of the Chemical Society 1949; S15–S25
  • Morris I. D., Williams L. M. Some preliminary observations of the nephrotoxicity of the male antifertility drug (±)α‐chlorohydrin. Journal of Pharmacy and Pharmacology 1980; 32: 35–38
  • Murray J. F., Nolen H. W., Gordon G. R., Peters J. H. The measurement of urinary oxalic acid by derivatization coupled with liquid chromatography. Analytical Biochemistry 1982; 121: 301–309
  • Nair P. V., Busch H. Improved synthesis of monofluoro‐ and monochloropyruvic acids. Journal of Organic Chemistry 1958; 23: 137–139
  • Porter K. E., Jones A. R. The effect of the isomers of α‐chlorohydrin and racemic β‐chlorolactate on the rat kidney. Chemico‐Biological Interactions 1982; 41: 95–104
  • Porter K. E., Jones A. R. The renal toxicity of (R)‐3‐chlorolactate in the rat. Chemico‐Biological Interactions 1987; 62: 157–166
  • Reed L. J., Mukherjee B. B. α‐Ketoglutarate dehydrogenase complex from Escherichia coli. Methods in Enzymology, J. M. Lowenstein. Academic Press, New York 1969; Vol. 13: 55–61
  • Terada H., Hayashi T., Kawai S., Ohno T. High‐performance liquid chromatographic determination of pyruvic acid and α‐ketoglutaric acid in serum. Journal of Chromatography 1977; 130: 281–286
  • Udenfriend S., Clark C. T., Axelrod J., Brodie B. Ascorbic acid in aromatic hydroxylation. 1. A model for aromatic hydroxylation. Journal of Biological Chemistry 1954; 208: 731–739
  • Vogel A. Textbook of Practical Organic Chemistry4th edn., B. S. Furmss, A. J. Hannaford, V. Rogers, P. W. G. Smith, A. R. Tatchell. Longman, New York 1978; 1111
  • Welt L. G. The Pharmacological Basis of Therapeutics4th edn., L. S. Goodman, A. Gilman. Macmillan, London 1970; 773

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