Influence of medium composition on 7-alkoxycoumarin O-dealkylase activities of rat hepatocytes in primary maintenance culture

References

• Boobis A. R., Nebert D. W., Felton J. S. Comparisons of β-naphthoflavone and 3-methylcholanthrene as inducers of hepatic cytochrome (s) P448 and aryl hydrocarbon (benzo [a] pyrene) hydroxylase activity. Molecular Pharmacology 1977; 13: 259–268
   PubMed Web of Science ®Google Scholar
• Boobis A. R., Whyte C., Davies D. S. Selective induction and inhibition of the components of 7-ethoxycoumarin O-deethylase activity in the rat. Xenobiotica 1986; 16: 233–238
   PubMed Web of Science ®Google Scholar
• Bradford M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 1976; 72: 248–254
   PubMed Web of Science ®Google Scholar
• Burke M. D., Thompson S., Elcombe C. R., Halpert J., Haaparanta T., Mayer R. T. Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P450. Biochemical Pharmacology 1985; 34: 3337–3345
   PubMed Web of Science ®Google Scholar
• Edwards A. M., Glistak M. L., Lucas C. M., Wilson P. A. 7-ethoxycoumarin deethylase activity as a convenient measure of liver drug metabolizing enzymes: regulation in cultured rat hepatocytes. Biochemical Pharmacology 1985; 33: 1537–1546
   Google Scholar
• Erwin B. G., Stoscheck C. M., Flarini J. R. A rapid fluorometric method for the estimation of DNA in cultured cells. Analytical Biochemistry 1981; 110: 291–294
   PubMed Web of Science ®Google Scholar
• Forster U., Luippold G., Schwarz L. R. Induction of monooxygenase and UDP-glucuronosyltransferase activities in primary cultures of rat hepatocytes. Drug Metabolism and Disposition 1986; 14: 353–360
   PubMed Web of Science ®Google Scholar
• Fry J. R., Bridges J. W. The metabolism of 7-ethoxycoumarin in primary maintenance cultures of adult rat hepatocytes. Naunyn-Schmiedeberg's Archives of Pharmacology 1980; 311: 85–90
   PubMedGoogle Scholar
• Guengerich F. P., Dannan G. A., Wright S. T., Martin M. V., Kaminsky L. S. Purification and characterization of liver microsomal cytochromes P450: electrophoretic, spectral, catalytic and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or β-naphthoflavone. Biochemistry 1982; 21: 6019–6030
   PubMed Web of Science ®Google Scholar
• Heuman D. M., Gallagher E. J., Barwick J. L., Elshourbagy N. A., Guzelian P. S. Immunochemical evidence for induction of a common form of hepatic cytochrome P450 in rats treated with pregnenolone- 16α-carbonitrile or other steroidal or non-steroidal agents. Molecular Pharmacology 1982; 21: 753–760
   PubMed Web of Science ®Google Scholar
• Kamataki T., Ando M., Yamazoe Y., Ishii K., Kato R. Sex difference in the O-dealkylation activity of 7-hydroxycoumarin O-alkyl derivatives in liver microsomes of rats. Biochemical Pharmacology 1980; 29: 000–000
   Google Scholar
• Loury D. J., Hsieh D. P. H., Byard J. L. The effect of phenobarbitat-pretreatment on the metabolism, covalent binding, and cytotoxicity of aflatoxin B1 in primary cultures of rat hepatocytes. Journal of Toxicology and Environmental Health 1984; 13: 145–159
   PubMed Web of Science ®Google Scholar
• Mathis J. M., Prough R. A., Hines R. N., Bresnick E., Simpson E. R. Regulation of cytochrome P450c by glucocorticoids and polycyclic aromatic hydrocarbons in cultured fetal rat hepatocytes. Archives of Biochemistry and Biophysics 1986; 246: 439–448
   PubMed Web of Science ®Google Scholar
• Nims R. W., Prough R. A., Lubet R. A. Cytosol-mediated reduction of resorufin: a method for measuring quinone oxidoreductase. Archives of Biochemistry and Biophysics 1984; 229: 459–455
   PubMed Web of Science ®Google Scholar
• Orton T. C., Sorman A. E., Crisp D. M., Sturdee A. P. Dynamics of xenobiotic metabolism by isolated rat hepatocytes using a multichannel perifusion system. Xenobiotica 1983; 13: 743–753
   PubMed Web of Science ®Google Scholar
• Paterson P., Fry J. R. The effect of ascorbic acid on the conjugation of 4-hydroxybiphenyl in rat isolated hepatocytes. Xenobiotica 1983; 13: 607–610
   PubMed Web of Science ®Google Scholar
• Paterson P., Fry J. R., Horner S. A. Influence of cytochrome P450 type on the pattern of conjugation of 7-hydroxy-coumarin generated from 7-alkoxycoumarins. Xenobiotica 1984; 14: 849–859
   PubMed Web of Science ®Google Scholar
• Prough R. A., Burke M. D., Mayer R. T. Direct fluorometric methods for measuring mixed function oxidase activity. Methods in Enzymology, S. Fleischer, L. Packer. Academic Press, Inc., New York 1978; Vol. 52 Part C: 372–377
   Google Scholar
• Schuetz E. G., Wrighton S. A., Barwick J. L., Guzelian P. S. Induction of cytochrome P450 by glucocorticoids in rat liver. Journal of Biological Chemistry 1984; 259: 1999–2006
   PubMed Web of Science ®Google Scholar
• Simmons D. L., McQuiddy P., Kasper C. B. Induction of the hepatic mixed-function oxidase system by synthetic glucocorticoids. Journal of Biological Chemistry 1987; 262: 326–332
   PubMed Web of Science ®Google Scholar
• Steward A. R., Dannan G. A., Guzelian P. S., Guengerich F. P. Changes in the concentration of seven forms of cytochrome P450 in primary cultures of adult rat hepatocytes. Molecular Pharmacology 1985; 27: 125–132
   PubMed Web of Science ®Google Scholar
• Warren M., Fry J. R., Balls M. The effect of glucose, insulin and dexamethasone upon 7-ethoxycoumarin O-deethylase activity of adult rat hepatocytes in primary culture. Xenobiotica 1985; 15: 775–779
   PubMed Web of Science ®Google Scholar