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Xenobiotica
the fate of foreign compounds in biological systems
Volume 19, 1989 - Issue 11
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Research Article

Microsomal metabolism of fluoroanilines

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Pages 1297-1305 | Received 11 Jan 1989, Accepted 12 Apr 1989, Published online: 22 Sep 2008

References

  • Aymes J. D., Paris M. R. Etude des complexes du cobalt (II) transporteurs d'oxygène: nouvelle synthèse du fluoro-3 hydroxy-2-benzaldéhyde. Bulletin de la Société Chimique de France 1980; 3–4: II-175–II-178
  • Baldwin M. K., Hutson D. H. The metabolism of 3-chloro-4-fluoro-aniline in dog and rat. Xenobiotica 1980; 10: 135–144
  • Boyland E., Manson D., Sims P. The preparation of O-aminophenyl sulphates. Journal of the Chemical Society 1953; 3623–3628
  • Brodie B. B., Axelrod J. The estimation of acetanilide and its metabolic products, aniline, N-acetyl p-aminophenol and p-aminophenol (free and conjugated) in biological fluids and tissues. Journal of Pharmacological and Experimental Therapeutics 1948; 94: 22–28
  • Daly J. W., Guroff G., Udenfriend S., Witkop B. Hydroxylation of alkyl and halogen substituted anilines and acetanilides by microsomal hydroxylases. Biochemical Pharmacology 1968; 17: 31–36
  • Daly J. W., Jerina D. M., Witkop B. Arene oxides and the NIH shift: The metabolism, toxicity and carcinogenicity of aromatic compounds. Experientia 1972; 28: 1129–1149
  • Eadsforth C. V., Logan C. J., Morrison B. J., Warburton P. A. 2–4-Difluoroaniline and 4-fluoroaniline exposure: monitoring by methaemoglobin and urine analyses. International Archives of Occupational and Environmental Health 1984; 54: 223–232
  • Eadsforth C. V., Coveney P. C., Hutson D. H., Logan C. J., Samuel A. J. The metabolism of o-fluoroaniline by rats, rabbits and marmosets. Xenobiotica 1986; 16: 555–566
  • Grossman S. J., Jollow D. J. Use of the NIH shift to determine the relative contribution of competing pathways of aniline metabolism in the rat. Drug Metabolism and Disposition 1986; 14: 689–691
  • Renson J., Bourdon V. Hydroxylation et défluorination des dérivés fluores de l'aniline. Archives of International Pharmacodynamics 1968; 171: 240–242
  • Rutten A. A. J. J. L., Falke H. E., Catsburg J. F., Topp R., Blaauboer B. J., van Holsteijn I., Doorn L., van Leeuwen F. X. R. Interlaboratory comparison of total cytochrome P-450 and protein determinations in rat liver microsomes. Archives of Toxicology 1987; 61: 27–33
  • Ryan D. E., Jida S., Wood A. W., Thomas P. E., Lieber C. S., Levin W. Characterization of three highly purified cytochromes P-450 from hepatic microsomes of adult male rats. Journal of Biological Chemistry 1984; 259: 1239–1250
  • Shaka A. J., Keeler J., Freeman R. Evaluation of a new broad band decoupling sequence: Waltz 16. Journal of Magnetic Resonance 1983; 53: 313–340
  • Stewart F. P., Smith A. G. Metabolism of the ‘mixed’ cytochrome P-450 inducer hexachlorobenzene by rat liver microsomes. Biochemical Pharmacology 1986; 35: 2163–2170
  • Uehleke H., Hellmer K. H., Tabarelli S. Binding of 14C-carbon ‘tetrachloride’ to microsomal proteins in vitro and formation of CHCI3 by reduced liver microsomes. Xenobiotica 1973; 3: 1–11
  • Wray V. Annual Reports on NMR Spectroscopy, G. A. Webb. Academic Press, London 1983; Vol. 14: 252

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