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Xenobiotica
the fate of foreign compounds in biological systems
Volume 20, 1990 - Issue 12
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Original Article

A methylsulphonyl metabolite of a polychlorinated biphenyl can serve as a ligand for α-globulin in rat and major-urinary-protein in mice

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Pages 1343-1352 | Received 21 Dec 1989, Accepted 29 Jun 1990, Published online: 27 Aug 2009

References

  • Andersson Ö., Linder C.-E., Olsson M., Reutergårdh L., Uvemo U.-B., Wideqvist U. Spatial differences and temporal trends of organochloride compounds in biota from the northwestern hemisphere,. Archives of Environment Contamination and Toxicology 1988; 17: 755–765
  • Bakke J. E., Gustafsson J.-å. Mercapturic acid pathway metabolites of xenobiotics: generation of potentially toxic metabolites during enterohepatic circulation. Trends in Pharmacological Sciences 1984; 5: 517–521
  • Bakke J. E., Bergman å. L., Larsen G. L. Metabolism of 2,4′,5-trichlorobiphenyl by the mercapturic acid pathway. Science 1982; 217: 645–647
  • Bergman å., Wachtmeister C. A. Phase transfer mediated synthesis of radiolabeled alkyl aryl ethers and sulfides. Journal of Labelled Compounds and Radiopharmacology 1987; 24: 925–930
  • Borghoff S. J., Strasser J., Jr., Charbonneau M., Swenberg J. A. Analysis of 2,4,4-trimethyl-2-pentanol (TMP-OH) binding to male rat kidney α2μ-globulin (α2μ) and other proteins. Toxicologist 1988; 8: 135
  • Bradford M. H. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 1976; 72: 248–254
  • Brandt I., Bergman Å. Bronchial mucosal and kidney cortex affinity of 4- and 4,4′-substituted sulphur-containing derivatives of 2,2′,5,5′-tetrachlorobiphenyl in mice. Chemical and Biological Interactions 1981; 34: 47–55
  • Charbonneau M., Strassek J., Jr., Lock E. A., Turner M., Jr., Swenberg J. A. Involvement of reversible binding to α2μ-globulin in 1,4-dichlorobenzene-induced nephrotoxicity. Toxicology and Applied Pharmacology 1989; 99: 122–132
  • Crowle A. J. Double diffusion tests. Immuno Diffusion 2nd edn. Academic Press, New York 1973; 247–304
  • Haraguchi K., Kuroki H., Masuda Y. Occurrence and distribution of chlorinated aromatic methylsulfones and sulfoxide in biological samples,. Chemosphere 1989; 19: 487–492
  • Kato Y., Kogure T., Sata M., Murata T., Kimura R. Evidence that methylsulfonyl metabolites of m-dichlorobenzene are causative substances of induction of hepatic microsomal drug-metabolizing enzymes by the parent compound in rats. Toxicology and Applied Pharmacology 1986; 82: 505–511
  • Klasson-Wehler E., Bergman å. L., Wachtmeister C. A. Synthesis of 4,4′-bis([3H]methyl sulphonyl)-2,2′,5,5′-tetrachlorobiphenyl. Journal of Labeled Compounds and Radiopharmacology 1983; 20: 1407–1412
  • Larsen G. L. Distribution of cysteine conjugate β-lyase in gastrointestinal bacteria and in the environment. Xenobiotica 1985; 15: 199–209
  • Larsen G. L., Bakke J. E., Huwe J. K. Methylsulphone metabolites of m-dichlorobenzene as ligands for a2μ-globulin in rat kidney and urine. Xenobiotica 1990; 20: 7–17
  • Lehman-McKeeman L. D., Rodriquez P. A., Takigiku R., Caudill D., Fey M. L. d-Limonene-induced male rat-specific nephrotoxicity: evaluation of the association between d-limonene and α2μ-globulin. Toxicology and Applied Pharmacology 1989; 99: 250–259
  • Lund J., Nordlund L., Gustafsson J.-å. Partial purification of a binding protein for polychlorinated biphenyls from rat lung cytosol: physiochemical and immunochemical characterization. Biochemistry 1988; 27: 7891–7901
  • Mazel J. V., Jr. Polyacrylamide gel electrophoresis of viral proteins. Methods in Virology 1971; 5: 179–246
  • Mulford D. J. Metabolic fate of methylthio-containing xenobiotics in mammals. Thesis, North Dakota State University, Fargo 1986, ND 58105
  • Neuhaus O. W., Flory W. The effect of dietary protein on excretion of α2μ the sex-dependent protein of the adult male rat. Biochimica et Biophysica Acta 1975; 411: 74–86
  • Neuhaus O. W., Lerseth D. S. Dietary control of the renal reabsorption and excretion of α2μ-globulin. Kidney International 1979; 16: 409–415
  • Ouchterlony O. Handbook of Immunodiffusion and Immunoelectrophoresis. Ann Arbor Sci. Publ., Ann Arbor, MI 1968; 215
  • Preston B. D., Miller J. A., Miller E. C. Reactions of 2,2′,5,5′-tetrachlorobiphenyl-3,4-oxide with methionine, cysteine and glutathione in relation to the formation of methylthio-metabolites of 2,2′,5,5′-tetrachlorobiphenyl in the rat and mouse. Chemical and Biological Interactions 1984; 50: 289–312
  • Roy A. K., Neuhaus O. W. Proof of the hepatic synthesis of a sex-dependent protein in the rat. Biochimica et Biophysica Acta 1966; 127: 82–87
  • Royce P. C. Characterization of a renal dependent rat serum protein. American Journal of Physiology 1968; 215: 1429–1434
  • Stonard M. D., Foster J. R., Phillips P. G. N., Simpson M. G., Lock E. A. Hyaline droplet formation in rat kidney induced by 2,2,4,-trimethyl pentane. Renal Heterogenicity and Target Cell Toxicity, P. H. Bachy, E. A. Lock. Wiley, Chichester 1986; 485–488
  • Stone L. C., Kanerva R. L., Burns J. L., Alden C. L. Decalin-induced nephrotoxicity: the light and electron microscopic examination of the effects of oral dosing on development of kidney lesions in the rat. Food and Chemical Toxicology 1987; 24: 43–52
  • Swenberg J. A., Short B., Berghoff S., Strasser V., Charbonneau M. The comparative pathology of a2μ-globulin nephropathy. Toxicology and Applied Pharmacology 1989; 97: 35–46
  • Towbin H., Gordon J. Immunoblotting and dot immuno-binding-current status and outlook. Journal of Immunological Methods 1984; 72: 313–340

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