References
- Barrett A. J., Kembhavi A. A., Brown M. A., Kirschke H., Knight C. G., Tamai M., Hanada K. L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L. Biochemical Journal 1982; 210: 189–198
- Climie I. J., Hutson D. H., Stoydin G. Metabolism of the epoxy resin component 2,2-bis[4-(2,3-epoxypropoxy)phenyl]propane, the diglycidyl ether of bisphenol A(DGEBPA) in the mouse. Part II. Identification of metabolites in urine and faeces following a single oral dose of 14CDGEBPA. Xenobiotica 1981; 11: 401–424
- Eadsforth C. V., Hutson D. H., Logan C. J., Morrison B. J. The metabolism of n-butyl glycidyl ether in the rat and rabbit. Xenobiotica 1985; 15: 579–589
- Fukushima K., Arai M., Ogawa H., Suwa T., Satoh T. Identification of glutathione conjugate formed from loxistatin in rats. Xenobiotica 1989; 19: 521–529
- Fukushima K., Arai M., Suwa T., Satoh T. Enzymatic reduction of an epoxysuccinic acid derivative by rat cecal microflora. Drug Metabolism and Disposition 1990; 18: 264–266
- Hanada K., Tamai M., Morimoto S., Adachi T., Ohmura S., Sawada J., Tanaka I. Studies on thiol protease inhibitors. Part III. Inhibitory activities of E-64 derivatives on papain. Agricultural and Biological Chemistry 1978; 42: 537–541
- Hernandez O., Bend J. R. Metabolism of epoxides,. Metabolic Basis of Detoxication, W. B. Jakoby, J. R. Bend, J. Caldwell. Academic Press, New York 1982; 207–233
- Ivie G. W. Epoxide to olefin: a novel biotransformation in the rumen. Science 1976; 191: 959–961
- Kar N. C., Pearson C. M. Muscular dystrophy and activation of proteinases. Muscle and Nerve 1978; 1: 308–313
- Mori K., Senda S. Pheromone synthesis. 70. Synthesis of the enantiomers of cis-2-methyl-5-hexanolide, the major component of the sex pheromone of the carpenter bee. Tetrahedron 1985; 41: 541–546
- Tamai M., Matsumoto K., Ohmura S., Koyama I., Ozawa Y., Hanada K. In vitro and in vivo inhibition of cysteine proteinase by EST, a new analogue of E-64. Journal of Pharmacobio-Dynamics 1986; 9: 672–677
- Tamai M., Ohmura S., Kimura M., Hanada K., Sugita H. Prolongation of life span of dystrophic hamster by cysteine proteinase inhibitor, loxistatin (EST). Journal of Pharmacobio-Dynamics 1987; 10: 678–681
- Tamai M., Yokoo C., Murata M., Oguma K., Sota K., Sato E., Kanaoka Y. Efficient synthetic method for ethyl(+)-(2S,3S)-3-[(S)-3-methyl-1-(3-methylbutylcarbamoyl)butyl-carbamoyl]-2-oxiranecarboxylate (EST), a new inhibitor of cysteine proteinases. Chemical and Pharmaceutical Bulletin 1987; 35: 1098–1104
- Trager W. F., Jones J. P. Stereochemical considerations in drug metabolism,. Progress in Drug Metabolism, J. W. Bridges, L. F. Chasseaud, G. G. Gibson. Taylor & Francis, London 1987; Vol. 10: 55–83