Isolation of urinary p-hydroxylated metabolites of mephentermine and phentermine in male Wistar rats

M. A. Mori Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama, 930-01, Japan

N. Uy-yu Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama, 930-01, Japan

K. Sakai Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama, 930-01, Japan

M. Inoue Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama, 930-01, Japan

T. Miyahara Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama, 930-01, Japan

H. Kozuka Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama, 930-01, Japan

References

Cho A. K. The identification of p-hydroxyphentermine as a urinary metabolite of phentermine. Research Communications in Chemical Pathology and Pharmacology 1974; 7: 67–78
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Mori M., Uy-Yu N., Sakai K., Inoue M., Miyahara T., Kozuka H. Urinary and biliary metabolites of mephentermine in male Wistar rats. Xenobiotica 1989; 19: 287–299
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Walkenstein S. S., Chumkow N., Scifter J. Detoxication and excretion of mephentermine. Journal of Pharmacology and Experimental Therapeutics 1955; 115: 16–20
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Weischer V. M.-L., Opitz K. Bestimmung von Chlorphentermin. Fenfluramin und verwandten Substanzen im Harn. Arzneimittel-Forschung 1967; 17: 625–627
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Isolation of urinary p-hydroxylated metabolites of mephentermine and phentermine in male Wistar rats

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Isolation of urinary p-hydroxylated metabolites of mephentermine and phentermine in male Wistar rats

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