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Xenobiotica
the fate of foreign compounds in biological systems
Volume 21, 1991 - Issue 1
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Original Article

Kinetics of distribution and elimination of DDE in rats

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Pages 111-120 | Received 26 Mar 1990, Accepted 12 Jul 1990, Published online: 27 Aug 2009

References

  • Ando M. Dose-dependent excretion of DDE (1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene). Archives of Toxicology 1982; 49: 139–147
  • Apple E. Z. Thesis, University of Arizona. 1986
  • Bickel M. H., Mühlebach S. Pharmacokinetics and ecodisposition of polyhalogenated hydrocarbons: aspects and concepts. Drug Metabolism Reviews 1980; 11: 149–190
  • Dale W. E., Gaines T. B., Hayes W. J. Storage and excretion of DDT in starved rats. Toxicology and Applied Pharmacology 1962; 4: 89–106
  • Datta P. R. In vivo detoxication of p,p'-DDT via p,p'-DDE to p,p'-DDA in rats. Industrial Medicine and Surgery 1970; 39: 49–53
  • Di Francesco C., Bickel M. H. Uptake in vitro of lipophilic model compounds into adipose tissue preparations and lipids. Biochemical Pharmacology 1985; 34: 3683–3688
  • Durham W. F. Body burden of pesticides in man. Annals of the New York Academy of Sciences 1969; 160: 183–195
  • Fawcett S. C., King L. J., Bunyan P. J., Stanley P. I. The metabolism of 14C-DDT, 14C-DDD, 14-DDE and 14C-DDMU in rats and Japanese quail. Xenobiotica 1987; 17: 525–538
  • Geyer H., Scheunert I., Korte F. Bioconcentration potential of organic environmental chemicals in humans. Regulatory Toxicology and Pharmacology 1986; 6: 313–347
  • Hayes W. J. Review of metabolism of chlorinated hydrocarbon insecticides, especially in mammals. Annual Reviews of Pharmacology and Toxicology 1965; 5: 27–52
  • Hayes W. J., Jr, Dale W. E. Concentration of DDT in brain and other tissues in relation to symptomatology. Toxicology and Applied Pharmacology 1964; 6: 349
  • Jensen S., Jansson B. Methyl sulfone metabolites of PCB and DDE. Ambio 1976; 5: 257–260
  • Leighty E. G., Fentiman A. F., Jr, Thompson R. M. Conjugation of fatty acids to DDT in the rat: possible mechanism for retention. Toxicology 1980; 15: 77–82
  • Lutz R. J., Dedrick R. L., Matthews H. B., Eling T., Anderson M. W. A preliminary pharmacokinetic model for several isomers of polychlorinated biphenyls in the rat. Drug Metabolism and Disposition 1977; 5: 386–396
  • McIntosh J. E. A., McIntosh R. P. Mathematical Modelling and Computers in Endocrinology. Springer, Berlin-Heidelberg 1980
  • Meier J., Retting H., Hess H. Biopharmazie. Theorie und Praxis der Pharmakokinetik. Thième, Stuttgart 1981
  • Mühlebach S., Bickel M. H. Pharmacokinetics in rats of 2,4,5,2′,4′,5′-hexachlorobiphenyl, an unmetabolizable lipophilic model compound. Xenobiotica 1981; 11: 249–257
  • Mühlebach S., Wyss P. A., Bickel M. H. Comparative adipose tissue kinetics of thiopental, DDE, and 2,4,5,2′,4′,5′-hexachlorobiphenyl in the rat. Xenobiotica 1985; 15: 485–491
  • Peterson J. E., Robinson W. H. Metabolic products of p,p'-DDT in the rat. Toxicology and Applied Pharmacology 1964; 6: 321–327
  • Sundström G., Jansson B., Jensen S. Structure of phenolic metabolites of p,p'-DDE in rat, wild seal and guillemot. Nature 1975; 255: 627–628
  • To-Figueras J., Gomez-Catalan J., Rodamilans M., Corbella J. Mobilization of stored hexachlorobenzene and p,p'-dichlorodiphehylcholoroethylene during partial starvation in rats. Toxicology Letters 1988; 42: 79–86
  • Wyss P. A., Mühlebach S., Bickel M. H. Pharmacokinetics of 2,2′,4,4′,5,5′-hexachlorobiphenyl (6-CB) in rats with decreasing adipose tissue mass. I. Effects of restricting food intake two weeks after administration. Drug Metabolism and Disposition 1982; 10: 657–661
  • Wyss P. A., Mühlebach S., Bickel M. H. Long-term pharmacokinetics of 2,2′,4,4′,5,5′-hexachlorobiphenyl (6-CB) in rats with constant adipose tissue mass. Drag Metabolism and Disposition 1986; 14: 361–365

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