Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 21, 1991 - Issue 5
Submit an article Journal homepage
7
Views
5
CrossRef citations to date
0
Altmetric
Original Article

Influence of liver damage on antipyrine metabolite formation in rats

E. Tanaka Institute of Community Medicine, Tsukuba-shi, Ibaraki-ken, 305, Japan
,
H. Etoh Institute of Community Medicine, Tsukuba-shi, Ibaraki-ken, 305, Japan
,
A. Ishikawa Institute of Clinical Medicine, University of Tsukuba, Tsukuba-shi, Ibaraki-ken, 305, Japan
,
M. Nakanoh Division of Toxicology and Cellbiology, Department of Chemicobiological Interaction Research Center for Pathogenic Fungi and Microbiol Toxicoses, Chiba University, Chiba-ken, 280, Japan
&
S. Misawa Institute of Community Medicine, Tsukuba-shi, Ibaraki-ken, 305, Japan
Pages 663-667 | Received 16 Jun 1990, Accepted 08 Dec 1990, Published online: 27 Aug 2009

References

  • Burchell B., Coughtrie M. W. H. UDP-glucuronosyltransferases. Pharmacology and Therapeutics 1989; 43: 261–289
  • Danhof M., de Boer A. G., de Groot-van DER Vis E., Breimer D. D. Studies on the different metabolic pathways of antipyrine in rats: influence of phenobarbital and 3-methylcholan-threne treatment. Xenobiotica 1979; 9: 695–702
  • Danhof M., van Zuilen A., Boeijinaga J. K., Breimer D. D. Studies on different metabolic pathways of antipyrine in man. Oral versus intravenous administration and the influence of urinary collection time. European Journal of Clinical Pharmacology 1982; 21: 433–441
  • Tanaka E., Kinoshita H., Yoshida T., Kuroiwa Y. Determination of plasma trimethadione and its metabolite in carbon tetrachloride-intoxicated rat liver: a useful tool for estimation of hepatic drug-metabolizing capacity. Journal of Pharmacobio-Dynamics 1981; 4: 961–967
  • Tanaka E., Kinoshita H., Yoshida T., Kuroiwa Y. Trimethadione as a model drug for the evaluation of hepatic drug-metabolizing capacity in normal and α-naphthylisothiocyanate intoxicated rats. Pharmacology 1982a; 25: 202–209
  • Tanaka E., Kinoshita H., Yoshida T., Kuroiwa Y. Trimethadione as a model drug for the evaluation of hepatic drug-metabolizing capacity in normal and d-Galactosamine intoxicated rats. Japanese Journal of Pharmacology 1982b; 32: 1182–1185
  • Teunissen M. W. E., Meerburg-van DER Torren J. E., Vermeulen N. P. E., Breimer D. D. Automated HPLC-determination of antipyrine and its main metabolites in plasma, saliva and urine, indluding 4,4′-dihydroxyantipyrine. Journal of Chromatography 1983; 278: 367–378
  • Teunissen M. W. E. Factors and conditions affecting antipyrine clearance and metabolite formation. Thesis, 1984
  • Vesell E. S. The antipyrine test in clinical pharmacology: conceptions and misconceptions. Clinical Pharmacology and Therapeutics 1979; 26: 275–286
  • Watkins J. B., Gregus Z., Thompson T. N., Klaassen C. D. Induction studies on the functional heterogeneity of rat liver UDP-glucuronosyltransferases. Toxicology and Applied Pharmacology 1982; 64: 439–446

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.