Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 23, 1993 - Issue 6
Submit an article Journal homepage
25
Views
5
CrossRef citations to date
0
Altmetric
Research Article

Metabolism of phentermine and its derivatives in the male Wistar rat

M.-A. Mori School of Health Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812, Japan
,
H. Uemura Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama, 930-01, Japan
,
M. Kobayashi Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama, 930-01, Japan
,
T. Miyahara Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama, 930-01, Japan
&
H. Kozuka School of Health Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812, Japan
Pages 709-716 | Received 10 Nov 1992, Accepted 24 Mar 1993, Published online: 22 Sep 2008

References

  • Beckett A. H., Belanger P. M. The identification of three new metabolic products of phentermine after liver microsomal incubation. Xenobiotica 1974; 4: 509–519
  • Beckett A. H., Belanger P. M. The microsomalN-oxidation of phentermine. Journal of Pharmacy and Pharmacology 1976; 28: 692–699
  • Cho A. K. The identification ofp-hydroxyphentermine as a urinary metabolite of phentermine. Research Communications in Chemical Pathology and Pharmacology 1974; 7: 67–78
  • Cho A. K., Hodshon B. J., Lindeke B., Jonson J. Thep-hydroxylation of amphetamine and phentermine by rat liver microsomes. Xenobiotica 1975; 5: 531–538
  • Mori M., Uy-Yu N., Sakai K., Inoue M., Miyahara T., Kozuka H. Urinary and biliary metabolites of mephentermine in male Wistar rats. Xenobiotica 1989; 19: 287–299
  • Mori M., Uy-Yu N., Sakai K., Inoue M., Miyahara T., Kozuka H. Isolation of urinaryp-hydroxylated metabolites of mephentermine and phentermine in male Wistar rats. Xenobiotica 1990; 20: 653–656
  • Mori M., Kobayashi M., Sakai K., Nakafuka K., Mori Y., Kozuka H. The formation of metabolites of mephentermine by microsomal and cytosolic preparations of male Wistar rat livers. Xenobiotica 1992a; 22: 451–457
  • Mori M., Kobayashi M., Uemura H., Miyahara T., Kozuka H. Intestinal metabolism of mephentermine and its biliary metabolites in male Wistar rats. Xenobiotica 1992b; 22: 701–708
  • Mori M., Kobayashi M., Yumoto Y., Nakafuku K., Miyahara T., Kozuka H. Metabolism of mephentermine in male guinea pigs and male mice. Xenobiotica 1991; 21: 1301–1309
  • Weischer V. M.-L., Opitz K. Bestimmung von Chlorphentermin, Fenfluramin und verwandten Substanzen in Harn. Arzneimittel-Forschung 1967; 17: 625–627

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.