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Xenobiotica
the fate of foreign compounds in biological systems
Volume 25, 1995 - Issue 1
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Research Article

Dose-dependent induction of the microsomal monooxygenase system by phenobarbital and 3-methylcholanthrene in the ad libitum and calorie-restricted female rat

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Pages 17-26 | Received 21 Jun 1994, Published online: 22 Sep 2008

References

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  • Breckenridge A., Orme M. L. E., Davies L. Thorgeirsson, Dose-dependent enzyme induction. Clinical Pharmacology and
  • Burke M. D., Mayer R. T. Inherent specificities of purifi toward biphenyl hydroxylation and ethoxyresorufin deeth. Disposition 1975; 3: 245–253
  • Chou M. W., Pegram R. A., Turturro A., Holson R., Hart W. Effect of caloric restriction on the induction of hepatic cytochrome P450 and AH receptor binding in C57BL/6N DBA/2J mice. Drug and Chemical Toxicology 1993; 16: 1–19
  • Conney A. H. Induction of the microsomal enzymes by foreign c polycyclic aromatic hydrocarbons. G.H.A. Clowes Memoria 1982; 42: 4585–4917
  • Duffy P. H., Feuers R. J., Leakey J. A., Nakamura K. D., Turturro A., Hart R. W. Effect of chronic caloric restriction on the physiological variables related to energy metabolism in the male Fischer 344 rat. Mechanisms of Ageing and Development 1989; 48: 117–133
  • Fujino T., West D., Park S. S., Gelboin H. V. Studies on the mechanism of monoclonal antibody inhibition of enzyme activity of phenobarbital-induced cytochrome P-450. Pharmacology 1990; 40: 301–311
  • Henderson C. J., Russel A. L., Allan J. A., Wolf C. R. Sexual differentiation and regulation of P-450 CYP2C7. Biochimica et Biophysica Acta 1992; 1118: 99–106
  • Horbach G. J. M. J., Venkatraman J. T., Fernandes G. Food restriction prevents the loss of the isosafrole inducible cytochrome P450 mRNA and enzyme levels in aging rats. Biochemistry International 1990; 20: 725–730
  • Kawajiri K., Gotoh O., Tagashira Y., Sogawa K., Fujii-Kuriyama Y. Titration of mRNAs for cytochrome P450c and P450d under drug-inductive conditions in rat livers by their specific probes of cloned DNAs. Journal of Biological Chemistry 1984; 259: 10145–10149
  • Lewin W. Functional diversity of hepatic cytochromes P-450. Drug Metabolism and Disposition 1990; 18: 824–830
  • Lubet R. A., Mayer R. T., Cameron J. W., Nims R. W., Burke M. D., Wolff T., Guengerich F. P. Dealkylation of pentoxyresorufin: a rapid and sensitive assay for measuring induction of cytochrome(s) P450 by phenobarbital and other xenobiotics in the rat. Archives of Biochemistry and Biophysics 1985; 238: 43–48
  • Nakajima T., Elovarra E., Park S. S., Gelboin H. V., Hietanen E., Vainio H. Monoclonal antibody-directed characterization of benzene, ethoxyresorufin and pentoxyresorufin metabolism in rat liver microsomes. Biochemical Pharmacology 1990; 40: 1255–1261
  • Nash T. The calorimetric estimation of formaldehyde by means of the Hantzsch reaction. Biochemical Journal 1953; 55: 416–421
  • Nelson D. R., Kamataki T., Waxman D. J., Guengerich F. P., Estabrook R. W., Feyereisen R., Gonzalez F. J., Coon M. J., Gunsalus I C., Gotoh O., Okuda K., Nebert D. W. The P450 superfamily: Update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature. DNA and Cell Biology 1993; 12: 1–51
  • Okey A. B. Enzyme induction in the cytochrome P450 system. Pharmacology and Therapeutics 1990; 45: 241–298
  • Omura T., Sato R. The carbon monoxide-binding pigment of liver microsomes. II. Solubilization, purification and properties. Journal of Biological Chemistry 1964; 239: 2379–2385
  • Park S. S., Fujino T., Miller H., Guengerich F. P., Gelboin H. V. Monoclonal antibodies to phenobarbital-induced rat liver cytochrome P450. Biochemical Pharmacology 1984; 33: 2071–2081
  • Park S. S., Fujino T., West D., Guengerich F. P., Gelboin H. V. Monoclonal antibodies inhibiting enzyme activity of cytochrome P450 from 3-methylcholanthrene treated rats. Cancer Research 1982; 42: 1798–1808
  • Pohl R. J., Fouts J. R. A rapid method for assaying the metabolism of 7-ethoxyresorufin by microsomal subcellular fractions. Analytical Biochemistry 1980; 107: 150–155
  • Poland A., Glover E. Comparison of 2,3,7,8-tetrachlorodibenzo-p-dioxin, a potent inducer of aryl hydrocarbon hydroxylase, with 3-methylcholanthrene. Molecular Pharmacology 1974; 18: 349–359
  • Ricans L. E., Notley B. A. Differential effects of aging on hepatic microsomal monooxygenase induction by phenobarbital and β-naphthoflavone. Biochemical Pharmacology 1982; 31: 2339–2343
  • Ruckpaul K., Rein H. Cytochrome P450. Akademie, Berlin 1984
  • Skett P. Biochemical basis of sex differences in drug metabolism. Pharmacology and Therapeutics 1988; 38: 269–304
  • Tavoloni N., Jones M. J. T., Berk P. D. Dose-related effects of phenobarbital on hepatic microsomal enzymes. Proceedings of the Society for Experimental Biology and Medicine 1983; 174: 20–27
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