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Journal of Obstetrics and Gynaecology Volume 33, 2013 - Issue 5
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GYNAECOLOGY SHORT COMMUNICATION

Methylation of the HOXA10 homeobox gene promoter is associated with endometrial cancer: A pilot study

M. FambriniDepartment of Science for Woman and Child Health, University of Florence, Florence, ItalyCorrespondence[email protected]
,
C. BussaniDepartment of Science for Woman and Child Health, University of Florence, Florence, Italy
,
F. SorbiDepartment of Science for Woman and Child Health, University of Florence, Florence, Italy
,
A. PieralliDepartment of Science for Woman and Child Health, University of Florence, Florence, Italy
&
R. CioniDepartment of Science for Woman and Child Health, University of Florence, Florence, Italy
Pages 519-520 | Published online: 01 Jul 2013

References

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  • Rauch T, Wang Z, Zhang X, Zhong X, Wu X, Lau SK et al. 2007. Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assay. Proceedings of the National Academy of Sciences of the United States of America 104:5527–5532.
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  • Wu Y, Halverson G, Basir Z, Strawn E, Yan P, Guo SW. 2005. Aberrant methylation at HOXA10 may be responsible for its aberrant expression in the endometrium of patients with endometriosis. American Journal of Obstetrics and Gynecology 193:371–380.
  • Yoshida H, Broaddus R, Cheng W, Xie S, Naora H. 2006. Deregulation of the HOXA10 homeobox gene in endometrial carcinoma: role in epithelial-mesenchymal transition. Cancer Research 66:889–897.
  • Zhong G, Wang Y, Liu X. 2011. Expression of HOXA10 in endometrial hyperplasia and adenocarcinoma and regulation by sex hormones in vitro. International Journal of Gynecological Cancer 21:800–805.

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