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Journal of Obstetrics and Gynaecology Volume 5, 1985 - Issue 3
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Original Article

Direct DNA analysis for diagnosing fetal sickle status in first trimester chorion tissue

D. Maxwell Institute of Obstetrics and Gynaecology, Queen Charlotte's Maternity Hospital, London
,
R. Lilford Institute of Obstetrics and Gynaecology, Queen Charlotte's Maternity Hospital, London
,
J. Morsman Harris-Birthright Research Centre for Fetal Medicine, King's College Hospital Medical School, London
,
C. Rodeck Harris-Birthright Research Centre for Fetal Medicine, King's College Hospital Medical School, London
,
J. Old National Haemoglobin Reference Laboratory, John Radcliffe Hospital, Oxford
&
S. Thein National Haemoglobin Reference Laboratory, John Radcliffe Hospital, Oxford
Pages 133-135 | Published online: 02 Jul 2009

References

  • Chang J. C., Alberti A., Kan Y. W. A β-thalassaemia lesion abolishes the same Mst II site as the sickle mutation. Nucleic Acids Research 1983; 11: 7789–7794
  • Goossens M., Dumez Y., Kaplan L., Lupker M., Chabret C., Henrion R., Rosa J. Prenatal diagnosis of sickle-cell anemia in the first trimester of pregnancy. New England Journal of Medicine 1983; 309: 831–833
  • Kan Y. W., Dozy A. M. Antenatal diagnosis of sickle-cell anaemia by DNA analysis of amniotic-fluid cells. Lancet 1978; ii: 910–911
  • Old J. M., Higgs D. R. Gene analysis. The Thalassaemias; Methods in Haematology. Churchill Livingstone, Edinburgh 1983
  • Old J. M., Ward R. H. T., Karagözü F., Petrou M., Modell B., Weatherall D. J. First-trimester fetal diagnosis for haemoglobinopathies: Three cases. Lancet 1982; ii: 1413–1416
  • Rodeck C. H., Morsman J. M., Gosden C. M., Gosden J. R. Development of an improved technique for first-trimester microsampling of chorion. British Journal of Obstetrics and Gynaecology 1983; 90: 1113–1118
  • Rodeck C. H., Morsman J. M. First-trimester chorion biopsy. British Medical Bulletin 1983; 39: 338–342
  • Rodeck C. H., Nicolaides K. H. Fetoscopy and fetal tissue sampling. British Medical Bulletin 1983; 39: 332–337
  • Steinberg M. H., Hebbel R. P. Clinical diversity of sickle cell anaemia: Genetic and cellular modulation of disease severity. American Journal of Hematology 1983; 14: 405–416

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