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Research Article

Mitigative role of melatonin and α-tocopherol against mercury-induced genotoxicity

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Pages 221-226 | Received 19 Jan 2013, Accepted 28 Jul 2013, Published online: 06 Nov 2013

References

  • Akiyama M, Oshima H, Nakamura M. (2001). Genotoxicity of mercury used in chromosome aberration tests. Toxicol In Vitro 15:463–467
  • Amorim MM, Mergler D, Bahia MO, et al. (2000). Cytogenetic damage related to low levels of methylmercury contamination in the Brazilian Amazon. An Acad Bras Cienc 72:497–507
  • Bano M, Bhatt DK. (2010). Ameliorative effect of combination of vitamin E, Vitamin C, alpha lipoic acid and stilbene resveratrol on lindane induced toxicity in mice olfactory lobe and cerebrum. Indian J Exp Biol 48:150–158
  • Bast A, Haenen GRMM. (2002). The toxicity of antioxidants and their metabolites. Environ Toxicol Pharmacol 11:251–258
  • Blask DE, Sauer LA, Dauchy RT. (2002). Melatonin as a chronobiotic/anticancer agent: cellular, biochemical, and molecular mechanisms of action and their implications for circadian-based therapy. Curr Top Med Chem 2:113–132
  • Cebulska-Wasilewska A, Panek A, Zabiński Z, et al. (2005). Occupational exposure to mercury vapour on genotoxicity and DNA repair. Mutat Res 586:102–114
  • Crespo-López ME, Herculano AM, Corvelo TC, Nascimento JLM. (2005). Mercury and neurotoxicity. Rev Neurol 40:441–447
  • Cuzzocrea S, Reiter RJ. (2002). Pharmacological actions of melatonin in acute and chronic inflammation. Curr Top Med Chem 2:153–166
  • Eisler R. (2004). Mercury hazards from gold mining to humans, plants, and animals. Rev Environ Contam Toxicol 181:139–198
  • Erie JC, Butz JA, Good JA, et al. (2005). Heavy metal concentrations in human eyes. Am J Ophthalmol 139:888–893
  • Gichner T, Znidar I, Száková J. (2008). Evaluation of DNA damage and mutagenicity induced by lead in tobacco plants. Mutat Res 652:186–190
  • Guerrero JM, Reiter RJ. (2002). Melatonin-immune system relationships. Curr Top Med Chem 2:167–179
  • Guha B, Das JK, Khuda-Bukhsh AR. (2007). Ameliorative effect of vitamin E supplementation on EMS induced genotoxicity in fish, Anabas testudineus. Ecotoxicol Environ Saf 68:63–70
  • Hungerford DA. (1965). Leucocytes cultured from small inocula of whole blood and the preparation of metaphase chromosomes by treatment with hypotonic KCl. Stain Technol 40:333–338
  • Kamal-Eldin A, Appelqvist LA. (1996). The chemistry and antioxidant properties of tocopherols and tocotreienols. Lipids 3:671–701
  • Kennaway DJ, Wright H. (2002). Melatonin and circadian rhythms. Curr Top Med Chem 2:199–209
  • Kontek R, Nowicka H. (2013). The modulatory effect of genotoxicity of irinotecan in normal human lymphocytes and cancer cells. Drug Chem Toxicol 36:335–342
  • Latt SA. (1974). Microflurometric analysis of DNA relication kinetics and sister chromatid exchanges in human chromosomes. J Histochem Cytochem 22:478–491
  • Lialiaris T, Lyratzopoulos E, Papachristou F, et al. (2008). Supplementation of melatonin protects human lymphocytes in vitro from the genotoxic activity of melphalan. Mutagenesis 23:347–354
  • Machlin LJ. (1991). Vitamin E. In: Machlin LJ, ed. Handbook of vitamins. New York: Dekker, 99–144
  • Morimoto K, Lijima S, Koizumi A. (1982). Selenite prevents the induction of sister chromatid exchanges by methyl mercury and mercuric chloride in human whole blood cultures. Mutat Res 102:183–192
  • Mottet NK, Vahter ME, Charleston JS, Friberg LT. (1997). Metabolism of methylmercury in the brain and its toxicological significance. In: Sigel A, Sigel H, eds. Metal ions in biological systems. New York: Marcel Dekker, 371–403
  • Nair SB, Jhala DD, Chinoy NJ. (2004). Mitigation of genotoxic effects of fluoride and arsenate by ascorbic acid in human lymphocytes culture. Fluoride 37:249–256
  • Perry P, Wolff S. (1974). New Giemsa method for the differential staining of sister chromatids. Nature 251:156–158
  • Popescu HI, Negru L, Lancranjan A. (1979). Chromosome aberrations induced by occupational exposure to mercury. Arch Environ Health 34:461–463
  • Raina R, Verma PK, Kant V. (2009). Ameliorative effect of alpha-tocopherol on cypermethrin induced oxidative stress and lipid peroxidation in Wistar rats. Int J Med Med Sci 1:396–399
  • Rao MV, Chinoy NJ, Suthar MB, Rajvanshi MI. (2001). Role of ascorbic acid on mercuric chloride-induced genotoxicity in human blood cultures. Toxicol In Vitro 15:649–654
  • Rao MV, Gangadharan B. (2008). Antioxidative potential of melatonin against mercury induced intoxication in spermatozoa in vitro. Toxicol In Vitro 22:935–942
  • Rao MV, Purohit AR. (2011). Neuroprotection by melatonin on mercury induced toxicity in the rat brain. Pharmacol Pharm 2:375–385
  • Rao MV, Sharma PSN. (2001). Protective effect of vitamin-E against mercuric chloride induced reproductive toxicity in male mice. Reprod Toxicol 15:705–712
  • Rao MV, Tiwari H. (2006). Amelioration of melatonin of chromosomal anomalies induced by arsenic and/or fluoride in human blood lymphocyte cultures. Fluoride 39:251–256
  • Reiter RJ. (1980). The pineal and its hormones in the control of reproduction in mammals. Endocr Rev 1:109–131
  • Reiter RJ, Melchiorri D, Sewerynek E, et al. (1995). A review of the evidence supporting melatonin’s role as an anti-oxidant. J Pineal Res 18:1–11
  • Reiter RJ, Tan DX, Mayo JC, et al. (2003). Melatonin as an antioxidant: biochemical mechanisms and pathophysiological implications in humans. Acta Biochimica Polonica 50:1129–1146
  • Sharma MK, Buettner GR. (1993). Interaction of vitamin C and vitamin E during free radical stress in plasma: an ESR study. Free Radic Biol Med 14:649–653
  • Sliwinski T, Rozej W, Morawiec-Bajda A, et al. (2007). Protective action of melatonin against oxidative DNA damage—chemical inactivation versus base-excision repair. Mutat Res 634:220–227
  • Susa N, Ueno S, Furukawa Y, et al. (1997). Potent protective effects of melatonin on chromium (VI)-induced DNA strand breaks, cytotoxicity and lipid peroxidation in primary cultures of rat hepatocytes. Toxicol Appl Pharmacol 144:377–384
  • Tan DX, Manchester LC, Burkhart S, Sainz RM. (2001). N-acetyl N-formyl 5-methoxynuramine, a biogenic amine and melatonin metabolite, functions as a potent anti-oxidant. FASEB J 15:2294–2296
  • Tappel AL. (1962). Vitamin E as the biological lipid anti-oxidant. Vit Horm 20:493–510
  • Verma RJ, Nair A. (2001). Ameliorative effect of vitamin E on aflatoxin induced lipid peroxidation in the testis of mice. Asian J Androl 3:217–221

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