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Drug and Chemical Toxicology Volume 5, 1982 - Issue 3
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Research Article

Subchronic Dermal Toxicity Study of Trichlorobenzene in the Rabbit

K. S. Rao Toxicology Research Laboratory Health and Environmental Sciences U.S.A. Dow Chemical, Midland, Michigan, 48640, USA
,
K. A. Johnson Toxicology Research Laboratory Health and Environmental Sciences U.S.A. Dow Chemical, Midland, Michigan, 48640, USA
&
J. W. Henck Toxicology Research Laboratory Health and Environmental Sciences U.S.A. Dow Chemical, Midland, Michigan, 48640, USA
Pages 249-263 | Published online: 27 Sep 2008

References

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  • Kociba R. J., Leong B. K.J., Hefner R. E., Jr. Subchronic Toxicity Study of 1,2,4-Trichlorobenzene in the Rat, Rabbit and Beagle Dog. Drug Chem. Toxicol (1981); 4: 229
  • Rimington C., Ziegler G. Experimental Porphyria in Rats Induced by Chlorinated Benzenes. Biochem Pharmacol (1963); 12: 1387
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  • Brown V. K. H., Muir C., Thorpe E. The Acute Toxicity and Skin Irritant Properties of 1,2,4-Trichlorobenzene. Ann. Occup. Hyg (1969); 12: 209
  • Powers M. B., Coate W. B., Lewis T. R. Repeated Topical Applications of 1,2,4-Trichlorobenzene. Effects on Rabbit Ears. Arch. Environ. Health (1975); 30: 165
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  • Laird C. W., Fox R. R., Mitchell B. P., Blau E. M., Schultz H. S. Effect of Strain and Age on Some Hematological Parameters in the Rabbit. Am. J. Physiol (1970); 218: 1613
  • De Matteis F., Prior B. E., Rimington C. Nervous and Biochemical Disturbances Following Hexachlorobenzene Intoxication. Nature (1961); 191: 363
  • Wada O., Yano Y., Urata G., Nakao K. Behavior of Hepatic Microsomal Cytochromes After Treatment of Mice with Drugs Known to Disturb Porphyrin Metabolism in Liver. Biochem Pharmacol (1968); 17: 595
  • Goldstein J. A., Hickman P., Bergman H., Vos J. G. Hepatic Prophyria Induced by 2,3,7,8-Tetrachlorodibenzo-p-dioxane in the Mouse. Res. Comm. Chem. Path. Pharmacol (1973); 6: 919
  • Goldstein J. A., Hickman P., Jue D. L. Experimental Hepatic Porphyria Induced by Poiychlorinated Biphenyls. Toxicol. Appl. Pharmacol (1974); 27: 437
  • Grote W., Schmaldt H., Benthe H. F. Hepatic Porphyrin Synthesis in Rats After Pretreatment with Polychlorinated Biphenyls (PCB's). Acta Pharmacol, et Toxicol (1975); 36: 215

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