13
Views
5
CrossRef citations to date
0
Altmetric
Research Article

Changes in the Cardiovascular Nitric Oxide Pathway in Cyclosporin-A Treated Rats

, &
Pages 27-34 | Published online: 27 Sep 2008

References

  • Myers B. D., Ross J., Newton L., Luetscher J., Perlroth M. Cyclosporine-associated chronic nephropathy. N. Engl. J. Med (1984); 311: 699–705
  • Kirk A. J.B., Omar I., Bateman D. N., Dark J. H. Cyclosporine-associated hypertension in cardiopulmonary transplantation. The beneficial effect of nifedipine on renal function. Transplantation (1989); 48: 428–430
  • Rego A., Vargas R., Foegh M. L., Ramwell P. W. Effect of cyclosporine A treatment on vascular reactivity of the rat thoracic aorta. Transplant Proc. (1988); 20: 572–577
  • Bossaller C., Forstermann U., Hertel R., Olbricht C., Reschke V., Fleck E. Cyclosporin A inhibits endothelium-dependent vasodilatation and vascular prostacyclin production. Eur. J. Pharmacol. (1989); 165: 165–169
  • Cartier R., Carrier M., Dagenais F., Buluran J., Leclerc Y. Cyclosporine impedes endothelium-dependent coronary artery vasodilatation in the isolated rat heart. Transplant Proc. (1994); 26: 2877–2879
  • Banijamali H. S., ter Keurs M. H.C., ter Keurs H. E.D.J., Paul L. C. Effect of cyclosporine on myocardial contractility in the rat. Transplant Proc. (1994); 26: 2880–2882
  • Colombani P. M., Robb A, Hess A. D. Cyclosporin A binding to calmodulin: a possible site of action on T lymphocytes. Science (1985); 228: 337–339
  • Altschuld R. A., Hohl C. M., Castillo L. C., Garleb A. A., Starling R. C., Brierley G. P. Cyclosporin inhibits mitochondrial calcium efflux in isolated adult rat ventricular cardiomyocytes. Am. J. Physiol. (1992); 262: H1699–H1704
  • Gallego M. J., Lopez A., Farre Riesco A., Monton M., Grandes S. M., Barat A., Hernando L., Casaso S., Caramelo C. A. Blockade of endothelium-dependent responses in conscious rats by cyclosporin A: effect of L-arginine. Am. J. Physiol. (1993); 264: H708–H714
  • Dawson T. M., Steiner J. P., Dawson V. L., Dinerman J. L., Uhl G. R., Snyder S. H. Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity. Proc. Natl. Acad. Sci. USA (1993); 90: 9808–9812
  • Levy M. M., Ketchum R. J., Perloff J. R., Park D. H., Brayman K. L. Cyclosporin A inhibits nitric oxide production in an in vitro xenogeneic islet/splenocyte co-culture system. Transplant Proc. (1994); 26: 2886–2887
  • Welch G., Loscalzo J. Nitric oxide and the cardiovascular system [Review]. J. Card Surg. (1994); 9: 361–371
  • Bredt D. S., Snyder S. H. Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. Proc. Natl. Acad. Sci. USA (1990); 87: 682–685
  • Knowles R. G., Salter M., Brooks S. L., Moncada S. Anti-inflammatory glucocorticiods inhibit the induction by endotoxin of nitric oxide synthase in the lung, liver. and aorta of the rat. Biochem. Biophys. Res. Commun. (1990); 172: 1042–1048
  • Hutcheson A. E., Rao M. R., Olinde K. D., Markov A. K. Myocardial toxicity of cyclosporin A: inhibition of calcium ATPase and nitric oxide synthase activities and attenuation by fructose-1,6-diphosphate in vitro. Res. Commun. Mol. Pathol. Pharmacol. (1995); 89: 17–26
  • Guarner C., Soriano G., Tomas A., Bulbena O., Novella M. T., Balanzo J., Vilardell F., Mourelle M., Moncada S. Increased serum nitrite and nitrate levels in patients with cirrhosis: relationship to endotoxemia. Hepatology (1993); 18: 1139–1143
  • Oguchi S., Iida S., Adachi H., Ohshima H., Esumi H. Induction of Ca2+/calmodulin-dependent NO synthase in various organs of rats by Propionibacterium acnes and lipopolysaccharide treatment. FEBS Letters (1992); 308: 22–25
  • Stuehr D. J., Marietta M A. Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide. Proc. Natl. Acad. Sci. USA (1985); 82: 7738–7742
  • Marietta M A, Yoon P. S., Iyengar R., Leaf C. D., Wishnok J. S. Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate. Biochemistry (1988); 27: 8706–8711

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.