Association Between Polymorphisms in Genes Encoding Methylenetetrahydrofolate Reductase and the Risk of Ménière's Disease

REFERENCES

• Antoniades, C., Shirodaria, C., Leeson, P., Baarholm, O. A., Van-Assche, T., Cunnington, C., Pillai, R., Ratnatunga, C., Tousoulis, D., Stefanadis, C., Refsum, H., & Channon, K.M. (2009). MTHFR 677C>T polymorphism reveals functional importance for 5-methyltetrahydrofolate, not homocysteine, in regulation of vascular redox state and endothelial function in human atherosclerosis. Circulation, 119, 2507–2515.
   PubMed Web of Science ®Google Scholar
• Barbara, P., Rajiv, K., Alessio, N., Rashmi, B. P., Asta, F., Veronika, P., Ludmila, V., & Jan, N. (2011). MTHFR and MTRR genotype and haplotype analysis and colorectal cancer susceptibility in a case-control study from the Czech Republic. Mutat Res, 721, 74–80.
   Google Scholar
• Campbell, C. A., Della Santina, C. C., Meyer, N. C., Smith, N. B., Myrie, O. A., Stone, E. M., Fukushima, K., Califano, J., Carey, J. P., Hansen, M. R., Gantz, B. J., Minor, L. B., & Smith, R. J. (2010). Polymorphisms in KCNE1 or KCNE3 are not associated with Ménière disease in the Caucasian population. Am J Med Genet A, 152A, 67–74.
   PubMed Web of Science ®Google Scholar
• Capaccio, P., Ottaviani, F., Cuccarini, V., Ambrosetti, U., Fagnani, E., Bottero, A., Cenzuales, S., Cesana, B. M., & Pignataro, L. (2005). Sudden hearing loss and MTHFR 677C > T/1298A > C gene polymorphisms. Genet Med, 7, 206–208.
   PubMedGoogle Scholar
• Chen, J., Ma, J., Stampfer, M. J., Palomeque, C., Selhub, J., & Hunter, D. J. (2002). Linkage disequilibrium between the 677C > T and 1298A > C polymorphisms in human methylenetetrahydrofolate reductase gene and their contributions to risk of colorectal cancer. Pharmacogenetics, 12, 339–342.
   PubMedGoogle Scholar
• Committee on Hearing and Equilibrium. (1995). Committee on Hearing and Equilibrium guidelines for the diagnosis and evaluation of therapy in Meniere’s disease. Otolaryngol Head Neck Surg, 113, 181–185.
   PubMed Web of Science ®Google Scholar
• Das, P. M., & Singal, R. (2004). DNA methylation and cancer. J Clin Oncol, 22, 4632–4642.
   PubMed Web of Science ®Google Scholar
• Doi, K., Sato, T., Kuramasu, T., Hibino, H., Kitahara, T., Horii, A., Matsushiro, N., Fuse, Y., & Kubo, T. (2005). Ménière's disease is associated with single nucleotide polymorphisms in the human potassium channel genes, KCNE1 and KCNE3. ORL J Otorhinolaryngol Relat Spec, 67, 289–293.
   PubMedGoogle Scholar
• Durga, J., Anteunis, LJ., Schouten, E. G., Bots, M. L,, Kok, F. J., & Verhoef, P. (2006). Association of folate with hearing is dependent on the 5,10-methylenetetrahdyrofolate reductase 677C→T mutation. Neurobiol Aging27, 482–489.
   Google Scholar
• Everett, L. A., Belyantseva, I. A., Noben-Trauth, K., Cantos, R., Chen, A., Thakkar, S. I., Hoogstraten-Miller, S. L., Kachar, B., Wu, D. K., & Green, E. D (2001). Targeted disruption of mouse Pds provides insight about the inner-ear defects encountered in Pendred syndrome. Hum Mol Genet, 10, 153–161.
   PubMed Web of Science ®Google Scholar
• Fransen, E., Verstreken, M., Verhagen, W. I., Wuyts, F. L., Huygen, P. L., D’Haese, P., Robertson, N. G., Morton, C. C., McGuirt, W. T., Smith, R. J., Declau, F., Van de Heyning, P. H., & Van Camp, G. (1999). High prevalence of symptoms of Meniére’s disease in three families with a mutation in the COCH gene. Hum Mol Genet, 8, 1425–1429.
   PubMed Web of Science ®Google Scholar
• Frosst, P., Blom, H. J., Milos, R., Goyette, P., Sheppard, C. A., Matthews, R. G., Boers, G., den Heijer, M., Kluijtmans, L. A., van den Heuve, L. P., & Rozen, R. (1995). A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase. Nat Genet, 10, 111–113.
   PubMed Web of Science ®Google Scholar
• Gazquez, I., Lopez-Escamez, J. A., Moreno, A., Campbell, C. A., Meyer, N. C., Carey, J. P., Minor, L. B., Gantz, B. J., Hansen, M. R., Della Santina, C., Aran, I., Soto-Varela, A., Santos, S., Batuecas, A., Perez-Garrigues, H., Lopez-Nevot, A., Smith, R. J. H., & Lopez- Nevot, M. A. (2011). Functional variants in NOS1 and NOS2A are not associated with progressive hearing loss in Ménière's disease in an European Caucasian population. DNA Cell Biol, 30, 699–708.
   PubMed Web of Science ®Google Scholar
• Gross, M., Friedman, G., Eliashar, R., Koren-Morag, N., Goldschmidt, N., Atta, I. A., & Ben-Yehuda, A. (2006). Impact of methionine synthase gene and methylenetetrahydrofolate reductase gene polymorphisms on the risk of sudden sensorineural hearing loss. Audiol Neurootol, 11, 287–293.
   PubMedGoogle Scholar
• Hirota, Y., Ohara, T., Zenibayashi, M., Kuno, S., Fukuyama, K., Teranishi, T., Kouyama, K., Miyake, K., Maeda, E., & Kasuga, M. (2007). Lack of association of CPT1A polymorphisms or haplotypes on hepatic lipid content or insulin resistance in Japanese individuals with type 2 diabetes mellitus. Metabolism, 56, 656–661.
   PubMedGoogle Scholar
• Hung, R. J., Hashibe, M., McKay, J., Gaborieau, V., Szeszenia- Dabrowska, N., Zaridze, D., Lissowska, J., Rudnai, P., Fabianova, E., Mates, I., Foretova, L., Janout, V., Bencko, V., Chabrier, A., Moullan, N., Canzian, F., Hall, J., Boffetta, P., & Brennan, P. (2007). Folate related genes and the risk of tobacco-related cancers in Central Europe. Carcinogenesis, 28, 1334–1340.
   Google Scholar
• Kawaguchi, S., Hagiwara, A., & Suzuki, M. (2008). Polymorphic analysis of the heat-shock protein 70 gene (HSPA1A) in Ménière's disease. Acta Otolaryngol, 128, 1173–1177.
   PubMed Web of Science ®Google Scholar
• Lievers, K. J., Kluijtmans, L. A., van der Put, N. M., Trijbels, F. J., & Blom, H. J. (2001). A second common variant in the methylenetetrahydrofolate reductase (MTHFR) gene and its relationship to MTHFR enzyme activity, homocysteine, and cardiovascular disease risk. J Mol Med, 79, 522–528.
   PubMed Web of Science ®Google Scholar
• Lopez-Escamez, J. A., Moreno, A., Bernal, M., Perez-Garrigues, H., Santos-Perez, S., Soto-Varela, A., Aran, I., Fernandez- Sanfrancisco, O., Lopez-Nevot, A., & Lopez-Nevot, M. A. (2009). Poly (ADP-Ribose) Polymerase-1 (PARP-1) longer alleles spanning the promoter region may confer protection to bilateral Meniere's disease. Acta Otolaryngol, 129, 1222–1225.
   PubMed Web of Science ®Google Scholar
• Lopez-Escamez, J. A., Saenz-Lopez, P., Acosta, L., Moreno, A., Gazquez, I., Perez-Garrigues, H., Lopez-Nevot, A., & Lopez-Nevot, M. A. (2010). Association of a functional polymorphism of PTPN22 encoding a lymphoid protein phosphatase in bilateral Meniere's disease. Laryngoscope, 120, 103–107.
   PubMed Web of Science ®Google Scholar
• Lopez-Escamez, J. A., Saenz-Lopez, P., Gazquez, I., Moreno, A., Gonzalez-Oller, C., Soto-Varela, A., Santos, S., Aran, I., Perez- Garrigues, H., Ibañez, A., & Lopez-Nevot, M. A. (2011). Polymorphisms of CD16A and CD32 Fcgamma receptors and circulating immunocomplexes in Ménière's disease: A case-control study. BMC Med Genet, 12, 2.
   PubMed Web of Science ®Google Scholar
• Lopez-Escamez, J. A., Vilchez, J. R., Soto-Varela, A., Santos-Perez, S., Perez-Garrigues, H., Aran, I., & Lopez-Nevot, M. A. (2007). HLADRB1* 1101 allele may be associated with bilateral Ménière's disease in southern european population. Otol Neurotol, 28, 891–895.
   PubMed Web of Science ®Google Scholar
• Lynch, M., Cameron, T. L., Knight, M., Kwok, T. Y., Thomas, P., Forrest, S. M., Giersch, A. B., Briggs, R. J., & Pyman, B. C. (2002). Structural and mutational analysis of antiquitin as a candidate gene for Meniére’s disease. Am J Med Genet, 110, 397–399.
   PubMed Web of Science ®Google Scholar
• McDermott, A. P., Mills, J. L., Molloy, A. M., Carroll, N., Kirke, P. N., Cox, C., Conley, M. R., Pangilinan, F. J., Brody, L. C., & Scott, J. M. (2006). The MTHFR 1298CC and 677TT genotypes have opposite associations with red cell folate levels. Mol Genet Metab, 88, 290–294.
   Google Scholar
• Mhatre, A. N., Jero, J., Chiappini, I., Bolasco, G., Barbara, M., & Lalwani, A. K. (2002). Aquaporin-2 expression in the mammalian cochlea and investigation of its role in Meniere's disease. Hear Res, 170, 59–69.
   PubMed Web of Science ®Google Scholar
• Morrison, A. W. (1995). Anticipation in Meniére’s disease. J Laryngol Otol, 109, 499–502.
   PubMedGoogle Scholar
• Neumann, A. S., Lyons, H. J., Shen, H., Liu, Z., Shi, Q., Sturgis, E. M., Shete, S., Spitz, M. R., El-Naggar, A., Hong, W. K., & Wei, Q. (2005). Methylenetetrahydrofolate reductase polymorphisms and risk of squamous cell carcinoma of the head and neck: A case-control analysis. Int J Cancer, 115, 131–136.
   Google Scholar
• Robien, K., & Ulrich, C. M. (2003). 5,10-Methylenetetrahydrofolate reductase polymorphisms and leukemia risk: A HuGE minireview. Am J Epidemiol, 157, 571–582.
   PubMed Web of Science ®Google Scholar
• Sanchez, E., Lopez-Escamez, J. A., Lopez-Nevot, M. A., Lopez- Nevot, A., Cortes, R., & Martin, J. (2004). Absence of COCH mutations in patients with Meniere disease. Eur J Hum Genet, 12, 75–78.
   PubMed Web of Science ®Google Scholar
• Sohn, K. J., Jang, H., Campan, M., Weisenberger, D. J., Dickhout, J., Wang, Y. C., Cho, R. C., Yates, Z., Lucock, M., Chiang, E. P., Austin, R. C., Choi, S. W., Laird, P. W., & Kim, Y. I. (2009). The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: A possible molecular basis for the site-specific cancer risk modification. Int J Cancer, 124, 1999–2005.
   PubMed Web of Science ®Google Scholar
• Teggi, R., Lanzani, C., Zagato, L., Delli Carpini, S., Manunta, P., Bianchi, G., & Bussi, M. (2008). Gly460Trp alpha-adducin mutation as a possible mechanism leading to endolymphatic hydrops in Ménière's disease. Otol Neurotol, 29, 824–828.
   PubMed Web of Science ®Google Scholar
• Uchida, Y., Nakashimat, T., Ando, F., Niino, N., & Shimokata, H. (2005). Is there a relevant effect of noise and smoking on hearing? A population-based aging study. Int J Audiol, 44, 86–91.
   PubMed Web of Science ®Google Scholar
• Uchida, Y., Sugiura, S., Ando, F., Nakashima, T., & Shimokata, H. (2011). Hearing impairment risk and interaction of folate metabolism related gene polymorphisms in an aging study. BMC Med Genet, 12, 35.
   PubMed Web of Science ®Google Scholar
• Uchida, Y., Sugiura, S., Ando, F., Shimokata, H., & Nakashima, T. (2010). Association of the C677T polymorphism in the methylenetetrahydrofolate reductase gene with sudden sensorineural hearing loss. Laryngoscope, 120, 791–795.
   PubMed Web of Science ®Google Scholar
• Usami, S., Takahashi, K., Yuge, I.; Ohtsuka, A., Namba, A., Abe, S., Fransen, E., Patthy, L., Otting, G., & van Camp, G. (2003). Mutations in the COCH gene are a frequent cause of autosomal dominant progressive cochleo-vestibular dysfunction, but not of Meniere's disease. Eur J Hum Genet, 11, 744–748.
   PubMed Web of Science ®Google Scholar
• Yang, Q., Bailey, L., Clarke, R., Flanders, W. D., Liu, T., Yesupriya, A., Khoury, M. J., & Friedman, J. M. (2012). Prospective study of methylenetetrahydrofolate reductase (MTHFR) variant C677T and risk of all-cause and cardiovascular disease mortality among 6000 US adults. Am J Clin Nutr, 95, 1245–1253.
   PubMed Web of Science ®Google Scholar