Effects of transgenic expression of botulinum toxins in Drosophila

References

• Bateman, J.R. (2006). Site-specific transformation of Drosophila via C31 integrase-mediated cassette exchange. Genetics, 173, 769–777.
   PubMed Web of Science ®Google Scholar
• Bischof, J., Maeda, R.K., Hediger, M., Karch, F., & Basler, K. (2007). An optimized transgenesis system for Drosophila using germ-line-specific phiC31 integrases. Proceedings of the National Academy of Sciences of the United States of America, 104, 3312–3317.
   PubMed Web of Science ®Google Scholar
• Brand, A.H., & Perrimon, N. (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development, 118, 401–415.
   PubMed Web of Science ®Google Scholar
• Bruns, D., & Jahn, R. (2002). Molecular determinants of exocytosis. Pflügers Archiv: European Journal of Physiology, 443, 333–338.
   PubMed Web of Science ®Google Scholar
• Buchner, E. (1976). Elementary movement detectors in an insect visual system. Biological Cybernetics, 24, 85–101.
   Web of Science ®Google Scholar
• Chen, Y.A., & Scheller, R.H. (2001). SNARE-mediated membrane fusion. Nature Reviews: Molecular Cell Biology, 2, 98–106.
   PubMed Web of Science ®Google Scholar
• Chin, A.C., Burgess, R.W., Wong, B.R., Schwarz, T.L., & Scheller, R.H. (1993). Differential expression of transcripts from syb, a Drosophila melanogaster gene encoding VAMP (synaptobrevin) that is abundant in non-neuronal cells. Genetics, 131, 175–181.
   Google Scholar
• De Haro, L., Quetglas, S., Iborra, C., Lévêque, C., & Seagar, M. (2003). Calmodulin-dependent regulation of a lipid binding domain in the v-SNARE synaptobrevin and its role in vesicular fusion. Biology of the Cell, 95, 459–464.
   PubMed Web of Science ®Google Scholar
• Di Giovanni, J., Iborra, C., Maulet, Y., Lévêque, C., El Far, O., & Seagar, M. (2010). Calcium-dependent regulation of SNARE-mediated membrane fusion by calmodulin. Journal of Biological Chemistry, 285, 23665–23675.
   PubMed Web of Science ®Google Scholar
• DiAntonio, A., Burgess, R.W., Chin, A.C., Deitcher, D.L., Scheller, R.H., & Schwarz, T.L. (1993). Identification and characterization of Drosophila genes for synaptic vesicle proteins. Journal of Neuroscience, 13, 4924–4935.
   PubMed Web of Science ®Google Scholar
• Dietzl, G., Chen, D., Schnorrer, F., Su, K.-C., Barinova, Y., Fellner, M., … Dickson, B.J. (2007). A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila. Nature, 448, 151–156.
   PubMed Web of Science ®Google Scholar
• Freeman, M. (1996). Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye. Cell, 87, 651–660.
   PubMed Web of Science ®Google Scholar
• Graf, M., Bojak, A., Deml, L., Bieler, K., Wolf, H., & Wagner, R. (2000). Concerted action of multiple cis-acting sequences is required for Rev dependence of late human immunodeficiency virus type 1 gene expression. Journal of Virology, 74, 10822–10826.
   PubMed Web of Science ®Google Scholar
• Han, D.D., Stein, D., & Stevens, L.M. (2000). Investigating the function of follicular subpopulations during Drosophila oogenesis through hormone-dependent enhancer-targeted cell ablation. Development, 127:573–583.
   PubMed Web of Science ®Google Scholar
• Heisenberg, M., & Buchner, E. (1977). The role of retinula cell types in visual behavior of Drosophila melanogaster. Journal of Comparative Physiology, 117, 127–162.
   Web of Science ®Google Scholar
• Hua, S.Y., & Charlton, M.P. (1999). Activity-dependent changes in partial VAMP complexes during neurotransmitter release. Nature Neuroscience, 2, 1078–1083.
   PubMed Web of Science ®Google Scholar
• Hua, S.-Y., Raciborska, D.A., Trimble, W.S., & Charlton, M.P. (1998). Different VAMP/synaptobrevin complexes for spontaneous and evoked transmitter release at the crayfish neuromuscular junction. Journal of Neurophysiology, 80, 3233–3246.
   PubMed Web of Science ®Google Scholar
• Li, W.-Z., Li, S.-L., Zheng, H.Y., Zhang, S.-P., & Xue, L. (2012). A broad expression profile of the GMR-GAL4 driver in Drosophila melanogaster. Genetics and Molecular Research, 11, 1997–2002.
   PubMed Web of Science ®Google Scholar
• Luo, L., Liao, Y.J., Jan, L.Y., & Jan, Y.N. (1994). Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion. Genes and Development, 8, 1787–1802.
   PubMed Web of Science ®Google Scholar
• McGuire, S.E., Le, P.T., Osborn, A.J., Matsumoto, K., & Davis, R.L. (2003). Spatiotemporal rescue of memory dysfunction in Drosophila. Science, 302, 1765–1768.
   PubMed Web of Science ®Google Scholar
• McMahon, H.T., Ushkaryov, Y.A., Edelmann, L., Link, E., Binz, T., Niemann, H., … Südhof, T.C. (1993). Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein. Nature, 364, 346–349.
   PubMed Web of Science ®Google Scholar
• Neuser, K., Triphan, T., Mronz, M., Poeck, B., & Strauss, R. (2008). Analysis of a spatial orientation memory in Drosophila. Nature, 453, 1244–1247.
   PubMed Web of Science ®Google Scholar
• Niemeyer, B.A., & Schwarz, T.L. (2000). SNAP-24, a Drosophila SNAP-25 homologue on granule membranes, is a putative mediator of secretion and granule-granule fusion in salivary glands. Journal of Cell Science, 113, 4055–4064.
   PubMed Web of Science ®Google Scholar
• Pellizzari, R., Rossetto, O., Lozzi, L., Giovedi, S., Johnson, E., Shone, C.C., & Montecucco, C. (1996). Structural determinants of the specificity for synaptic vesicle-associated membrane protein/synaptobrevin of tetanus and botulinum type B and G neurotoxins. Journal of Biological Chemistry, 271, 20353–20358.
   PubMed Web of Science ®Google Scholar
• Pfeiffer, B.D., Ngo, T.-T.B., Hibbard, K.L., Murphy, C., Jenett, A., Truman, J.W., & Rubin, G.M. (2010). Refinement of tools for targeted gene expression in Drosophila. Genetics, 186, 735–755.
   PubMed Web of Science ®Google Scholar
• Prashad, R.C., & Charlton, M.P. (2014). SNARE zippering and synaptic strength. PLoS one, 9, e95130.
   PubMed Web of Science ®Google Scholar
• Rister, J., & Heisenberg, M. (2006). Distinct functions of neuronal synaptobrevin in developing and mature fly photoreceptors. Journal of Neurobiology, 66, 1271–1284.
   PubMedGoogle Scholar
• Sakaba, T., Stein, A., Jahn, R., & Neher, E. (2005). Distinct kinetic changes in neurotransmitter release after SNARE protein cleavage. Science, 309, 491–494.
   PubMed Web of Science ®Google Scholar
• Sanyal, S. (2009). Genomic mapping and expression patterns of C380, OK6 and D42 enhancer trap lines in the larval nervous system of Drosophila. Gene Expression Patterns, 9, 371–380.
   PubMed Web of Science ®Google Scholar
• Schiavo, G., Matteoli, M., & Montecucco, C. (2000). Neurotoxins affecting neuroexocytosis. Physiological Reviews, 80, 717–766.
   PubMed Web of Science ®Google Scholar
• Schiavo, G., Shone, C.C., Bennett, M.K., Scheller, R.H., & Montecucco, C. (1995). Botulinum neurotoxin type C cleaves a single Lys-Ala bond within the carboxyl-terminal region of syntaxins. Journal of Biological Chemistry, 270, 10566–10570.
   PubMed Web of Science ®Google Scholar
• Schulze, K.L., Broadie, K., Perin, M.S., & Bellen, H.J. (1995). Genetic and electrophysiological studies of Drosophila syntaxin-1A demonstrate its role in nonneuronal secretion and neurotransmission. Cell, 80, 311–320.
   PubMed Web of Science ®Google Scholar
• Sikorra, S., Henke, T., Galli, T., & Binz, T. (2008). Substrate recognition mechanism of VAMP/synaptobrevin-cleaving clostridial neurotoxins. Journal of Biological Chemistry, 283, 21145–21152.
   PubMed Web of Science ®Google Scholar
• Spradling, A.C., & Rubin, G.M. (1982). Transposition of cloned P elements into Drosophila germ line chromosomes. Science, 218, 341–347.
   PubMed Web of Science ®Google Scholar
• Suster, M.L., & Bate, M. (2002). Embryonic assembly of a central pattern generator without sensory input. Nature, 416, 174–178.
   PubMed Web of Science ®Google Scholar
• Sweeney, S.T., Broadie, K., Keane, J., Niemann, H., & O'Kane, C.J. (1995). Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defects. Neuron, 14, 341–351.
   PubMed Web of Science ®Google Scholar
• Thum, A.S., Knapek, S., Rister, J., Dierichs-Schmitt, E., Heisenberg, M., & Tanimoto, H. (2006). Differential potencies of effector genes in adult Drosophila. Journal of Comparative Neurology, 498, 194–203.
   PubMed Web of Science ®Google Scholar
• Vaidyanathan, V.V., Yoshino, K., Jahnz, M., Dörries, C., Bade, S., Nauenburg, S., … Blinz, T. (1999). Proteolysis of SNAP-25 isoforms by botulinum neurotoxin types A, C, and E: domains and amino acid residues controlling the formation of enzyme-substrate complexes and cleavage. Journal of Neurochemistry, 72, 327–337.
   PubMed Web of Science ®Google Scholar
• Vilinsky, I., Stewart, B.A., Drummond, J., Robinson, I., & Deitcher, D.L. (2002). A Drosophila SNAP-25 null mutant reveals context-dependent redundancy with SNAP-24 in neurotransmission. Genetics, 162:259–271.
   PubMed Web of Science ®Google Scholar
• Washbourne, P., Pellizzari, R., Baldini, G., Wilson, M.C., & Montecucco, C. (1997). Botulinum neurotoxin types A and E require the SNARE motif in SNAP-25 for proteolysis. FEBS Letters, 418, 1–5.
   PubMed Web of Science ®Google Scholar
• Waterhouse, A.M., Procter, J.B., Martin, D.M.A., Clamp, M., & Barton, G.J. (2009). Jalview Version 2 – a multiple sequence alignment editor and analysis workbench. Bioinformatics, 25, 1189–1191.
   PubMed Web of Science ®Google Scholar
• White, K., Tahaoglu, E., & Steller, H. (1996). Cell killing by the Drosophila gene reaper. Science, 271, 805–807.
   PubMed Web of Science ®Google Scholar
• Xu, X.Z., Wes, P.D., Chen, H., Li, H.S., Yu, M., Morgan, S., … Montell, C. (1998). Retinal targets for calmodulin include proteins implicated in synaptic transmission. Journal of Biological Chemistry, 273, 31297–31307.
   PubMed Web of Science ®Google Scholar
• Zhang, Y.Q., Bailey, A.M., Matthies, H.J., Renden, R.B., Smith, M.A., Speese, S.D., … Broadie, K. (2001). Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function. Cell, 107, 591–603.
   PubMed Web of Science ®Google Scholar
• Zhu, Y., Nern, A., Zipursky, S.L., & Frye, M.A. (2009). Peripheral visual circuits functionally segregate motion and phototaxis behaviors in the fly. Current Biology, 19, 613–619.
   PubMed Web of Science ®Google Scholar