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Research Article

Acute effects of smoking and food consumption on breath condensate pH in healthy adults

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Pages 92-100 | Received 29 Mar 2010, Accepted 02 Sep 2010, Published online: 04 Dec 2010

REFERENCES

  • Montuschi P: Analysis of exhaled breath condensate in respiratory medicine: methodological aspects and potential clinical applications. Ther Adv Respir Dis. 2007;1:5–23.
  • Montuschi P, Mondino C, Koch P, Barnes PJ, Ciabattoni G: Effects of a leukotriene receptor antagonist on exhaled leukotriene E-4 and prostanoids in children with asthma. J Allergy Clin Immunol. 2006;118:347–353.
  • Montuschi P, Macagno F, Parente P, Valente S, Lauriola L, Ciappi G, Kharitonov SA, Barnes PJ, Ciabattoni G: Effects of cyclo-oxygenase inhibition on exhaled eicosanoids in patients with COPD. Thorax. 2005;60:827–833.
  • Hoffmeyer F, Raulf-Heimsoth M, Bruning T: Exhaled breath condensate and airway inflammation. Curr Opin Allergy Clin Immunol. 2009;9:16–22.
  • Corradi M, Gergelova P, Mutti A: Use of exhaled breath condensate to investigate occupational lung diseases. Curr Opin Allergy Clin Immunol. 2010;10:93–98.
  • Horváth I, Hunt J, Barnes PJ, Alving K, Antczak A, Baraldi E, Becher G, van Beurden WJ, Corradi M, Dekhuijzen R, Dweik RA, Dwyer T, Effros R, Erzurum S, Gaston B, Gessner C, Greening A, Ho LP, Hohlfeld J, Jobsis Q, Laskowski D, Loukides S, Marlin D, Montuschi P, Olin AC, Redington AE, Reinhold P, van Rensen EL, Rubinstein I, Silkoff P, Toren K, Vass G, Vogelberg C, Wirtz H, ATS/ERS Task Force on Exhaled Breath Condensate: Exhaled breath condensate: methodological recommendations and unresolved questions. Eur Respir J. 2005;26:523–548.
  • Kullmann T, Barta I, Antus B, Horváth I: Drinking influences exhaled breath condensate acidity. Lung. 2008;186:263–268.
  • Do R, Bartlett KH, Chu W, Dimich-Ward H, Kennedy SM: Within- and between-person variability of exhaled breath condensate pH and NH4+ in never and current smokers. Respir Med. 2008;102:457–463.
  • Do R, Bartlett KH, Dimich-Ward H, Chu W, Kennedy SM: Biomarkers of airway acidity and oxidative stress in exhaled breath condensate from grain workers. Am J Respir Crit Care Med. 2008;178:1048–1054.
  • Koczulla AR, Noeske S, Herr C, Jörres RA, Römmelt H, Vogelmeier C, Bals R: Acute and chronic effects of smoking on inflammation markers in exhaled breath condensate in current smokers. Respiration. 2009;79:61–67.
  • Mehta H, Nazzal K, Sadikot RT: Cigarette smoking and innate immunity. Inflamm Res. 2008;57:497–503.
  • Garey K, Neuhauser MM, Robbins RA, Danziger LH, Rubinstein I: Markers of inflammation in exhaled breath condensate of young healthy smokers. Chest. 2004;125:22–26.
  • Guatura SB, Martinez JA, Santos Bueno PC, Santos ML: Increased exhalation of hydrogen peroxide in healthy subjects following cigarette consumption. Sao Paulo Med J. 2000;118:93–98.
  • Nowak D, Antczak A, Krol M, Pietras T, Shariati B, Bialasiewicz P, Jeczkowski K, Kula P: Increased content of hydrogen peroxide in the expired breath of cigarette smokers. Eur Respir J. 1996;9:652–657.
  • Montuschi P, Collins JV, Ciabattoni G, Lazzeri N, Corradi M, Kharitonov SA, Barnes PJ: Exhaled 8-isoprostane as an in vivo biomarker of lung oxidative stress in patients with COPD and healthy smokers. Am J Respir Crit Care Med. 2000;162:1175–1177.
  • Montuschi P, Ragazzoni E, Valente S, Corbo G, Mondino C, Ciappi G, Ciabattoni G: Validation of 8-isoprostane and prostaglandin E(2) measurements in exhaled breath condensate. Inflamm Res. 2003;52:502–507.
  • Balint B, Donnelly LE, Hanazawa T, Kharitonov SA, Barnes PJ: Increased nitric oxide metabolites in exhaled breath condensate after exposure to tobacco smoke. Thorax. 2001;56:456–461.
  • Papaioannou AI, Koutsokera A, Tanou K, Kiropoulos TS, Tsilioni I, Oikonomidi S, Liadaki K, Pournaras S, Gourgoulianis KI, Kostikas K: The acute effect of smoking in healthy and asthmatic smokers. Eur J Clin Invest. 2010;40:103–109.
  • Kaić Rak A, Antonić K: Food and drink composition tables [Croatian]. Zagreb: Zavod za zaštitu zdravlja SR Hrvatske; 1990.
  • Quanjer PH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault JC: Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J. 1993;16:5–40.
  • Xue Y, Morris M, Ni L, Guthrie SK, Zubieta JK, Gonzalez K, McConnell DS, Domino EF: Venous plasma nicotine correlates of hormonal effects of tobacco smoking. Pharmacol Biochem Behav. 2010;95:209–215.
  • Ussher M, West R, Evans P, Steptoe A, McEwen A, Clow A, Hucklebridge F: Reduction in cortisol after smoking cessation among users of nicotine patches. Psychosom Med. 2006;68:299–306.
  • Boyce PD, Kim JY, Weissman DN, Hunt J, Christiani DC: pH increase observed in exhaled breath condensate from welding fume exposure. J Occup Environ Med. 2006;48:353–356.
  • International Agency for Research on Cancer: IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Smokeless Tobacco and Some Tobacco-Specific N-Nitrosamines Lyon, France: IARC; 2007;89.
  • Guerin MR: Chemical composition of cigarette smoke. In: Gori GB, Bock FG, eds. Banbury Report. A Safe Cigarette? New York: Cold Spring Harbour Laboratory; 1980:191–204.
  • Chen J, Higby R, Tian D, Tan D, Johnson MD, Xiao Y, Kellar KJ, Feng S, Shields PG: Toxicological analysis of low-nicotine and nicotine-free cigarettes. Toxicology. 2008;249:194–203.
  • Ferris Wayne G, Connolly GN, Henningfield JE: Brand differences of free-base nicotine delivery in cigarette smoke: the view of the tobacco industry documents. Tob Control. 2006;15:189–198.
  • Richter P, Pechacek T, Swahn M, Wagman V: Reducing levels of toxic chemicals in cigarette smoke: a new Healthy People 2010 objective. Public Health Rep. 2008;123:30–38.
  • Ding YS, Zhang L, Jain RB, Jain N, Wang RY, Ashley DL, Watson CH. Levels of tobacco-specific nitrosamines and polycyclic aromatic hydrocarbons in mainstream smoke from different tobacco varieties. Cancer Epidemiol Biomarkers Prev. 2008;17:3366–3371.
  • Liu C, Feng S, van Heemst J, McAdam KG: New insights into the formation of volatile compounds in mainstream cigarette smoke. Anal Bioanal Chem. 2010;396:1817–1830.
  • Bernhard D, Rossmann A, Wick G: Metals in cigarette smoke. IUBMB Life. 2005;57:805–809.
  • Hoffmann D, Hoffmann I: The changing cigarette: chemical studies and bioassays. In: Shopland DR, ed. Risks Associated With Smoking Cigarettes With Low Machine-Measured Yields of Tar and Nicotine. Bethesda, MD: US Department of Health and Human Services, National Institutes of Health, National Cancer Institute Smoking and Tobacco Control Monograph (NIH), No. 13; 2001:159–191.
  • Seeman JI, Carchman RA: The possible role of ammonia toxicity on the exposure, deposition, retention, and the bioavailability of nicotine during smoking. Food Chem Toxicol. 2008;46:1863–1881.
  • Willems EW, Rambali B, Vleeming W, Opperhuizen A, van Amsterdam JG: Significance of ammonium compounds on nicotine exposure to cigarette smokers. Food Chem Toxicol. 2006;44:678–688.
  • Effros RM, Hoagland KW, Bosbous M, Castillo D, Foss B, Dunning M, Gare M, Lin W, Sun F: Dilution of respiratory solutes in exhaled condensates. Am J Respir Crit Care Med. 2002;165:663–669.
  • Effros RM, Biller J, Foss B, Hoagland K, Dunning MB, Castillo D, Bosbous M, Sun F, Shaker R: A simple method for estimating respiratory solute dilution in exhaled breath condensates. Am J Respir Crit Care Med. 2003;168:1500–1505.
  • Borrill ZL, Roy K, Singh D: Exhaled breath condensate biomarkers in COPD. Eur Respir J. 2008;32:472–486.
  • Zacharasiewicz A, Wilson N, Lex C, Li A, Kemp M, Donovan J, Hooper J, Kharitonov SA, Bush A: Repeatability of sodium and chloride in exhaled breath condensates. Pediatr Pulmonol. 2004;37:273–275.
  • Kharitonov SA, Barnes PJ: Exhaled biomarkers. Chest. 2006;130:1541–1546.
  • Vaughan J, Ngamtrakulpanit L, Pajewski TN, Turner R, Nguyen TA, Smith A, Urban P, Hom S, Gaston B, Hunt J: Exhaled breath condensate pH is a robust and reproducible assay of airway acidity. Eur Respir J. 2003;22:889–894.
  • Shreiner RH, Pratt KW: Standard Reference Materials: Primary Standards and Standard Reference Materials for Electrolytic Conductivity. Washington, DC: National Institute of Standards and Technology (NIST); 2004. NIST Special Publication 260–142
  • Van Der Vaart H, Postma DS, Timens W, ten Hacken NH: Acute effects of cigarette smoke on inflammation and oxidative stress: a review. Thorax. 2004;59:713–721.
  • Van Der Vaart H, Postma DS, Timens W, Hylkema MN, Willemse BW, Boezen HM, Vonk JM, de Reus DM, Kauffman HF, ten Hacken NH: Acute effects of cigarette smoking on inflammation in healthy intermittent smokers. Respir Res. 2005;6:18–22.
  • Walter S, Nancy NR: Basopenia following cigarette smoking. Indian J Med Res. 1980;72:422–425.
  • Singh SP, Kalra R, Puttfarcken P, Kozak A, Tesfaigzi J, Sopori ML: Acute and chronic nicotine exposures modulate the immune system through different pathways. Toxicol Appl Pharmacol. 2000;164:65–72.
  • Laan M, Bozinovski S, Anderson GP: Cigarette smoke inhibits lipopolysaccharide-induced production of inflammatory cytokines by suppressing the activation of activator protein-1 in bronchial epithelial cells. J Immunol. 2004;173:4164–4170.
  • Hunt J: Exhaled breath condensate: an evolving tool for noninvasive evaluation of lung disease. J Allergy Clin Immunol. 2002;110:28–34.
  • Baker EH, Clark N, Brennan AL, Fisher DA, Gyi KM, Hodson ME, Philips BJ, Baines DL, Wood DM: Hyperglycemia and cystic fibrosis alter respiratory fluid glucose concentrations estimated by breath condensate analysis. J Appl Physiol. 2007;102:1969–1975.
  • Marek E, Muckenhoff K, Streckert HJ, Becher G, Marek W: Measurements of l-lactate and H2O2 in exhaled breath condensate at rest and mild to moderate exercise in young and healthy subjects. Pneumologie. 2008;62:541–517.
  • Effros RM, Casaburi R, Su J, Dunning M, Torday J, Biller J, Shaker R: The effects of volatile salivary acids and bases on exhaled breath condensate pH. Am J Respir Crit Care Med. 2006;173:386–392.
  • Lopez de Bocanera ME, Koss de Stisman MA, Bru de Labanda E, Chervonagura de Gepner A: Statistical analysis of salivary pH changes after the intake of black tea and yerba mate supplemented with sweeteners. J Oral Sci. 1999;41:81–85.
  • Moazzez R, Smith BGN, Bartlett DW: Oral pH and drinking habit during ingestion of a carbonated drink in a group of adolescents with dental erosion. J Dent. 2000;28:395–397.
  • Avsar A, Darka O, Topaloglu B, Bek Y: Association of passive smoking with caries and related salivary biomarkers in young children. Arch Oral Biol. 2008;53:969–974.
  • Carpagnano GE, Spanevello A, Sabato R, Depalo A, Turchiarelli V, Foschino Barbaro MP: Exhaled pH, exhaled nitric oxide, and induced sputum cellularity in obese patients with obstructive sleep apnea syndrome. Transl Res. 2008;151:45–50.
  • Bondesson E, Jansson LT, Bengtsson T, Wollmer P: Exhaled breath condensate: site and mechanisms of formation. J Breath Res. 2009;3:016005(6).
  • Sapey E, Bayley D, Ahmad A, Stockley R: The validation of assays used to measure biomarkers in exhaled breath condensate. Eur Respir J. 2008;32:1408–1409.
  • Riediker M, Danuser B: Exhaled breath condensate pH is increased after moderate exercise. J Aerosol Med. 2007;20:13–18.
  • Kullmann T, Barta I, Antus B, Valyon M, Horváth I: Environmental temperature and relative humidity influence exhaled breath condensate pH. Eur Respir J. 2008;31:474–475.
  • Horváth I, Lazar Z, Gyulai N, Kollai M, Losonczy G: Exhaled biomarkers in lung cancer. Eur Respir J. 2009;34:261–275.
  • Gianazza E, Allegra L, Bucchioni E, Eberini I, Puglisi L, Blasi F, Terzano C, Wait R, Sirtori CR: Increased keratin content detected by proteomic analysis of exhaled breath condensate from healthy persons who smoke. Am J Med. 2004;117:51–54.
  • Kelsen SG, Duan X, Ji R, Perez O, Liu C, Merali S: Cigarette smoke induces an unfolded protein response in the human lung: a proteomic approach. Am J Respir Cell Mol Biol. 2008;38:541–550.
  • Bloemen K, Hooyberghs J, Desager K, Witters E, Schoeters G: Non-invasive biomarker sampling and analysis of the exhaled breath proteome. Proteomics Clin Appl. 2009;3:498–504.
  • Steiling K, Kadar AY, Bergerat A, Flanigon J, Sridhar S, Shah V, Ahmad QR, Brody JS, Lenburg ME, Steffen M, Spira A: Comparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokers. PLoS One. 2009;4:e5043. doi: 10.1371/journal.pone.0005043.
  • Montuschi P, Nightingale JA, Kharitonov SA, Barnes PJ: Ozone-induced increase in exhaled 8-isoprostane in healthy subjects is resistant to inhaled budesonide. Free Radic Biol Med. 2002;33:1403–1408.
  • de Laurentiis G, Paris D, Melck D, Maniscalco M, Marsico S, Corso G, Motta A, Sofia M: Metabonomic analysis of exhaled breath condensate in adults by nuclear magnetic resonance spectroscopy. Eur Respir J. 2008;32:1175–1183.

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