REFERENCES
- Burgel PR, Nadel JA: Roles of epidermal growth factor receptor activation in epithelial cell repair and mucin production in airway epithelium. Thorax. 2004;59:992–996.
- Puddicombe SM, Polosa R, Richter A, Krishna MT, Howarth PH, Holgate ST, Davies DE: Involvement of the epidermal growth factor receptor in epithelial repair in asthma. FASEB J. 2000;14:1362–1374.
- Denning DW, O'Driscoll BR, Hogaboam CM, Bowyer P, Niven RM: The link between fungi and severe asthma: a summary of the evidence. Eur Respir J. 2006;27:615–626.
- Gao FS, Qiao JO, Zhang Y, Jin XQ: Chronic intranasal administration of Aspergillus fumigatus spores leads to aggravation of airway inflammation and remodeling in asthmatic rats. Respirology. 2009;14:360–370.
- Gao FS, Gao YY, Liu MJ, Liu YQ: Chronic Aspergillus fumigatus exposure upregulates the expression of mucin 5AC in the airways of asthmatic rats. Exp Lung Res. 2012;38:256–265
- Palmans E, Kips JC, Pauwels RA: Prolonged allergen exposure induces structural airway changes in sensitized rats. Am J Respir Crit Care Med. 2000;161:627–635.
- Denis O, van den Brûle S, Heymans J, Havaux X, Rochard C, Huaux F, Huygen K: Chronic intranasal administration of mould spores or extracts to unsensitized mice leads to lung allergic inflammation, hyper-reactivity and remodelling. Immunology. 2007;122:268–278.
- Glaab T, Mitzner W, Braun A, Ernst H, Korolewitz R, Hohlfeld JM, Krug N, Hoymann HG: Repetitive measurements of pulmonary mechanics to inhaled cholinergic challenge in spontaneously breathing mice. J Appl Physiol. 2004;97:1104–1111.
- Sumi Y, Foley S, Daigle S, L'Archevêque J, Olivenstein R, Letuvé S, Malo JL, Hamid Q: Structural changes and airway remodelling in occupational asthma at a mean interval of 14 years after cessation of exposure. Clin Exp Allergy. 2007;37:1781–178.
- Snibson KJ, Bischof RJ, Slocombew RF, Meeusen EN: Airway remodelling and inflammation in sheep lungs after chronic airway challenge with house dust mite. Clin Exp Allergy. 2005;35:146–152.
- Leigh R, Ellis R, Wattie J, Southam DS, De Hoogh M, Gauldie J, O'Byrne PM, Inman MD: Dysfunction and remodeling of the mouse airway persist after resolution of acute allergen-induced airway inflammation. Am J Respir Cell Mol Biol. 2002;27:526–535.
- Ou XM, Feng YL, Wen FQ, Wang K, Yang J, Deng ZP, Liu DS, Li YP: Macrolides attenuate mucus hypersecretion in rat airways through inactivation of NF-κB. Respirology. 2008;13: 63–72.
- Engelhart S, Hanfland J, Glasmacher A, Krizek L, Schmidt-Wolf IG, Exner M: Impact of portable air filtration units on exposure of haematology–oncology patients to airborne Aspergillus fumigatus spores under field conditions. J Hosp Infect. 2003;54:300–304.
- Rivera A, Hohl T, Pamer EG: Immune response to Aspergillus fumigatus infections. Biol Blood Marrow Transplant. 2006;12:47–49.
- Holgate ST, Lackie P, Wilson S, Roche W, Davies D: Bronchial epithelium as a key regulator of airway allergen sensitization and remodeling in asthma. Am J Respir Crit Care Med 2000;162:S113–S117.
- Holgate ST: The airway epithelium is central to the pathogenesis of asthma. Allergol Int. 2008;57:1–10.
- Kauffman HF, Tomee JF, van de Riet MA, Timmerman AJ, Borger P: Protease-dependent activation of epithelial cells by fungal allergens leads to morphologic changes and cytokine production. Allergy Clin Immunol. 2000;105:1185–1193.
- Kohri K, Ueki IF, Shim JJ, Burgel PR, Oh YM, Tam DC, Dao-Pick T, Nadel JA: Pseudomonas aeruginosa induces MUC5AC production via epidermal growth factor receptor. Eur Respir J. 2002;20:1263–1270.
- Shao MX, Ueki IF, Nadel JA: Tumor necrosis factor alpha-converting enzyme mediates MUC5AC mucin expression in cultured human airway epithelial cells. Proc Natl Acad Sci USA. 2003;100:11618–11623.
- Takeyama K, Jung B, Shim JJ, Burgel PR, Dao-Pick T, Ueki IF, Protin U, Kroschel P, Nadel JA: Activation of epidermal growth factorreceptors is responsible for mucin synthesis induced by cigarette smoke. Am J Physiol Lung Cell Mol Physiol. 2001;280:L165–172.
- Takeyama K, Dabbagh K, Jeong Shim J, Dao-Pick T, Ueki IF, Nadel JA: Oxidative stress causes mucinsynthesis via transactivation of epidermal growth factor receptor: role ofneutrophils. J Immunol. 2000;164:1546–1552.
- Shim JJ, Dabbagh K, Ueki IF, Dao-Pick T, Burgel PR, Takeyama K, Tam DC, Nadel JA: IL-13 induces mucin production bystimulating epidermal growth factor receptors and by activating neutrophils. Am J Physiol Lung Cell Mol Physiol. 2001;280:L134–L140.
- Thai P, Loukoianov A, Wachi S, Wu R: Regulation of airway mucin gene expression. Annu Rev Physiol. 2008;70: 405–429.
- Takeyama K, Tamaoki J, Kondo M, Isono K, Nagai A: Role of epidermal growth factor receptor in maintaining airway goblet cell hyperplasia in rats sensitized to allergen. Clin Exp Allergy. 2008;38:857–865.