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ORIGINAL ARTICLE

Hypoxia-induced acute lung injury is aggravated in Streptozotocin diabetic mice

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Pages 146-154 | Received 04 May 2014, Accepted 25 Oct 2014, Published online: 16 Dec 2014

REFERENCES

  • American Diabetes association: Diagnosis and classification of diabetes mellitus. Diabetes Care. 2009;32(Suppl 1):S62–S67.
  • Cade WT: Diabetes-related microvascular and macrovascular diseases in the physical therapy setting. Phys Ther. 2008;88:1322–1335.
  • Goldman MD: Lung dysfunction in diabetes. Diabetes Care. 2003;26:1915–1918.
  • Frohlich S, Boylan J, McLoughlin P: Hypoxia-induced inflammation in the lung: a potential therapeutic target in acute lung injury? Am J Respir Cell Mol Biol. 2013;48:271–279.
  • Eltzschig HK, Carmeliet P: Hypoxia and inflammation. N Engl J Med. 2011;364:656–665.
  • Miura H, Wachtel RE, Loberiza FR, Saito T, Miura M, Nicolosi AC, Gutterman DD: Diabetes mellitus impairs vasodilation to hypoxia in human coronary arterioles: reduced activity of ATP-sensitive potassium channels. Circ Res. 2003;92:151–158.
  • Johnson DR, O'Connor JC, Hartman ME, Tapping RI, Freund GG: Acute hypoxia activates the neuroimmune system, which diabetes exacerbates. J Neurosci. 2007;27:1161–1166.
  • Rosenberger C, Khamaisi M, Goldfarb M, Shina A, Shilo V, Zilbertrest F, Rosen S, Heyman SN: Acute kidney injury in the diabetic rat: studies in the isolated perfused and intact kidney. Am J Nephrol. 2008;28:831–839.
  • Isoe T, Makino Y, Mizumoto K, Sakagami H, Fujita Y, Honjo J, Takiyama Y, Itoh H, Haneda M: High glucose activates HIF-1-mediated signal transduction in glomerular mesangial cells through a carbohydrate response element binding protein. Kidney Int. 2010;78:48–59.
  • Wang Y, Ma YY, Song XL, Cai HY, Chen JC, Song LN, Yang R, Lu J: Upregulations of glucocorticoid-induced leucine zipper by hypoxia and glucocorticoid inhibit proinflammatory cytokines under hypoxic conditions in macrophages. J Immunol. 2012;188:222–229.
  • Zhang HX, Duan GL, Wang CN, Zhang YQ, Zhu XY, Liu YJ: Protective effect of resveratrol against endotoxemia-induced lung injury involves the reduction of oxidative/nitrative stress. Pulm Pharmacol Ther. 2014;27:150–155.
  • Yang T, Mao YF, Liu SQ, Hou J, Cai ZY, Hu JY, Ni X, Deng XM, Zhu XY: Protective effects of the free radical scavenger edaravone on acute pancreatitis-associated lung injury. Eur J Pharmacol. 2010;630:152–157.
  • Zhu X, Tang Z, Cong B, Du J, Wang C, Wang L, Ni X, Lu J: Estrogens increase cystathionine-gamma-lyase expression and decrease inflammation and oxidative stress in the myocardium of ovariectomized rats. Menopause. 2013;20:1084–1091.
  • Sies H: Oxidative stress: oxidants and antioxidants. Exp Physiol. 1997;82:291–295.
  • Devaraj S, Dasu MR, Park SH, Jialal I: Increased levels of ligands of Toll-like receptors 2 and 4 in type 1 diabetes. Diabetologia. 2009;52:1665–1668.
  • Filgueiras LR Jr, Martins JO, Serezani CH, Capelozzi VL, Montes MB, Jancar S: Sepsis-induced acute lung injury (ALI) is milder in diabetic rats and correlates with impaired NFkB activation. PLoS One. 2012;7:e44987.
  • Wright JK, Nwariaku FN, Clark J, Falck JC, Rogers T, Turnage RH: Effect of diabetes mellitus on endotoxin-induced lung injury. Arch Surg. 1999;134:1354–1358.
  • Bellmeyer A, Martino JM, Chandel NS, Scott Budinger GR, Dean DA, Mutlu GM: Leptin resistance protects mice from hyperoxia-induced acute lung injury. Am J Respir Crit Care Med. 2007;175:587–594.
  • Xiong XQ, Wang WT, Wang LR, Jin LD, Lin LN: Diabetes increases inflammation and lung injury associated with protective ventilation strategy in mice. Int Immunopharmacol. 2012;13:280–283.
  • MacNee W: Oxidative stress and lung inflammation in airways disease. Eur J Pharmacol. 2001;429:195–207.
  • Schumacker PT: Lung cell hypoxia: role of mitochondrial reactive oxygen species signaling in triggering responses. Proc Am Thorac Soc. 2011;8:477–484.
  • Izquierdo-Álvarez A, Ramos E, Villanueva J, Hernansanz-Agustín P, Fernández-Rodríguez R, Tello D, Carrascal M, Martínez-Ruiz A: Differential redox proteomics allows identification of proteins reversibly oxidized at cysteine residues in endothelial cells in response to acute hypoxia. J Proteomics. 2012;75:5449–5462.
  • Cai L, Kang YJ: Oxidative stress and diabetic cardiomyopathy: a brief review. Cardiovasc Toxicol. 2001;1:181–193.
  • Ha H, Kim KH: Pathogenesis of diabetic nephropathy: the role of oxidative stress and protein kinase C. Diabetes Res Clin Pract. 1999;45:147–151.
  • Kinalski M, Sledziewski A, Telejko B, Zarzycki W, Kinalska I: Lipid peroxidation and scavenging enzyme activity in streptozotocin-induced diabetes. Acta Diabetol. 2000;37: 179–183.
  • Ozansoy G, Güven C, Ceylan A, Can B, Aktan F, Oz E, Gönül B: Effects of simvastatin treatment on oxidant/antioxidant state and ultrastructure of streptozotocin-diabetic rat lung. Cell Biochem Funct. 2005;23:421–426.
  • Bonfigli A, Colafarina S, Falone S, Di Giulio C, Di Ilio C, Amicarelli F: High levels of antioxidant enzymatic defence assure good protection against hypoxic stress in spontaneously diabetic rats. Int J Biochem Cell Biol. 2006;38:2196–2208.
  • Rubenfeld GD, Caldwell E, Peabody E, Weaver J, Martin DP, Neff M, Stern EJ, Hudson LD: Incidence and outcomes of acute lung injury. N Engl J Med. 2005;353:1685–1693.
  • Zhou X, Dai Q, Huang X: Neutrophils in acute lung injury. Front Biosci. 2012;17:2278–2283.
  • MacNee W: Oxidative stress and lung inflammation in airways disease. Eur J Pharmacol. 2001;429:195–207.
  • King GL: The role of inflammatory cytokines in diabetes and its complications. J Periodontol. 2008;79:1527–1534.
  • Tuder RM, Yun JH, Bhunia A, Fijalkowska I: Hypoxia and chronic lung disease. J Mol Med. 2007;85:1317–1324.
  • Rassler B, Marx G, Reissig C, Rohling MA, Tannapfel A, Wenger RH, Zimmer HG: Time course of hypoxia-induced lung injury in rats. Respir Physiol Neurobiol. 2007;159: 45–54.
  • Yao L, Kan EM, Lu J, Hao A, Dheen ST, Kaur C, Ling EA: Toll-like receptor 4 mediates microglial activation and production of inflammatory mediators in neonatal rat brain following hypoxia: role of TLR4 in hypoxic microglia. J Neuroinflammation. 2013;10:23.
  • Kim SY, Choi YJ, Joung SM, Lee BH, Jung YS, Lee JY: Hypoxic stress up-regulates the expression of Toll-like receptor 4 in macrophages via hypoxia-inducible factor. Immunology. 2010;129:516–524.
  • Young KC, Hussein SM, Dadiz R, deMello D, Devia C, Hehre D, Suguihara C: Toll-like receptor 4-deficient mice are resistant to chronic hypoxia-induced pulmonary hypertension. Exp Lung Res. 2010;36:111–119.
  • Dasu MR, Devaraj S, Park S, Jialal I: Increased toll-like receptor (TLR) activation and TLR ligands in recently diagnosed type 2 diabetic subjects. Diabetes Care. 2010;33:861–868.
  • Devaraj S, Dasu MR, Rockwood J, Winter W, Griffen SC, Jialal I: Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: further evidence of a proinflammatory state. J Clin Endocrinol Metab. 2008;93:578–583.
  • Tewari R, Choudhury SR, Ghosh S, Mehta VS, Sen E: Involvement of TNFα-induced TLR4-NF-κB and TLR4-HIF-1α feed-forward loops in the regulation of inflammatory responses in glioma. J Mol Med. 2012;90:67–80.

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