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Original Article

Generation of Lipoxygenase Metabolites of Arachidonic Acid by Monolayer Cultures of Tracheal Epithelial Cells and Intact Tracheal Segments from Rabbits

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Pages 211-233 | Received 13 Sep 1988, Accepted 18 Aug 1989, Published online: 02 Jul 2009

References

  • Sirois P, Roy S, Tetrault J P, Bogeat P, Picard S, Corvey E J. Pharmacological activity of leukotrienes A, B, C, and D on selected guinea pig, rat, rabbit and human smooth muscles. Prostaglandins Med 1981; 7: 327–340
  • Ahmed T, Marchette B, Warner A, Yerger L. Direct and indirect effects of leukotriene D on the pulmonary and systemic circualtions. Am Rev Respir Dis 1985; 131: 554–558
  • Peck M J, Piper P J, Williams T J. The effect of leukotrienes C and D on the microvasculature of the guinea pig. Prostaglandins 1981; 21: 315–321
  • Marom Z, Shelhamer J GH, Bach M K, Morton D R, Kaliner M. Slow reacting substances, leukotrienes C and D, increase the release of mucus from human airways in vitro. Am Rev Respir Dis 1982; 126: 449–451
  • Johnson H G, McNee M L, Sun F F. 15-hydroxyeicosatetraenoic acid is a potent inflammatory mediator and agonist of canine tracheal mucus secretion. Am Rev Respir Dis 1985; 131: 917–922
  • Leikauf G D, Ueki I F, Widdicombe J H, Nadel J A. Alteration of chloride secretion across canine tracheal epithleium by lipoxygenase products of arachidonic acid. Am J Physiol 1986; 250: F47–F53
  • Palmer R MJ, Stepney R J, Higgs G A, Eakins K E. Chemotactic activity of arachidonic acid products on leukocytes of different species. Prostaglandins 1980; 20: 411–418
  • Smith M JH, Ford-Hutchinson A W, Bray M A. Leukotriene B: A potent mediator of inflammation. J Pharm Pharmacol 1980; 32: 517–518
  • Martin T R, Altman L C, Albert R K, Henderson W R. Leukotriene B produced by the human alveolar macrophage; A potential mechanism for amplifying inflammation in the lung. Am Rev Respir Dis 1984; 129: 106–111
  • Morganroth M L, Stenmark K R, Zirrolli J A, Mauldin R, Mathias M, Reeves J T, Murphy R C, Voelkel N F. Leukotriene C4 production during hypoxic pulmonary vasconstriction in isolated rat lungs. Prostaglandins 1984; 28: 867–875
  • Murray J J, Tonnel A B, Brash A R, Roberts L J, Gosset P, Workman R, Capron A, Oates J A. Release of prostaglandin D2 into human airways during acute antigen challenge. N Engl J Med 1986; 31: 800–804
  • Dahlen S E, Hansson G, Hedqvist P, Bjorck T, Granstrom E, Dahlen B. Allergen challenge of lung tissue from asthmatics elicits bronchial contraction that correlates with the release of leukotrienes C4 D4 and E4. Proc Natl Acad Sci USA 1983; 80: 1712–1716
  • Harvey J, Holgate S T, Peters B J, Robinson C, Walker J R. Oxidative transformations of arachidonic acid in human dispersed lung cells: Disparity between the utilization of endogenous and exogenous substrate. Br J Pharmacol 1985; 86: 417–426
  • Adler K B, Schwarz J E, Anderson W H, Welton A F. Platelet activating factor stimulates secretion of mucin by explants of rodent airways in organ culture. Exp Lung Res 1987; 13: 25–43
  • Butler G B, Adler K E, Evans J N, Morgan D W, Szarek J L. Modulaytion of rabbit airway smooth muscle responsiveness by respiratory epithelium. Am Rev Re-spir Dis 1987; 135: 1099–1104
  • Holtzman M J, Aizawa H, Nadel J A, Goetzl E J. Selective generation of leukotriene B4 by tracheal epithelial cells from dogs. Biochem Biophys Res Commun 1983; 114: 1071–1076
  • Hansbrough J R, Atlas A B, Turk J, Holtzman M J. Arachidonate 12-lipoxygenase and cyclooxygenase: PGE isomerase are predominant pathways for oxygenation in bovine tracheal epithelial cells. Am J Respir Cell Mol Biol 1989; 1: 237–244
  • Henke D H, Danilowicz R M, Boucher R C, Eling T E. Metabolism of arachidonic acid by human nasal and bronchial epithelial cells. Arch Biochem Biophys 1988; 267: 426–436
  • Holtzman M J, Hansbrough R J, Rosen G D, Turk J. Uptake, release and novel species-dependent oxygenation of arachidonic acid in human and animal airway epithelial cells. Biochim Biophys Acta 1988; 963: 401–413
  • Salari H, Chan-Yeung M. Release of 15-hydroxyeicosatetraenoic acid (15-HETE) and prostaglandin E2 (PGE2) by cultured human bronchial epithelial cells. Am J Respir Cell Mol Biol 1989; 1: 245–250
  • Churchill L, Chilton F H, Resau J H, Bascom R, Hubbard W C, Proud D. Cyclooxygenase metabolism of endogenous arachidonic acid by cultured human tracheal epithelial cells. Am Rev Respir Dis 1989; 140: 449–459
  • Xu G L, Sivarajah K, Wu R, Nettesheim P, Eling T. Biosynthesis of prostaglandins by isolated and cultured airway epithelial cells. Exp Lung Res 1986; 10: 101–114
  • Alpert S E, Hayes M M, Brashler J R, Bach M K. Generation of lipoxygenase metabolites of arachidonic acid by confluent monolayer cultures of rabbit tracheal epithelial cells. Am Rev Respir Dis 1987; 135: A318
  • Duniec Z M, Eling T E, Jetten A M, Gray T E, Nettesheim P. Arachidonic acid metabolism in normal and transformed rat tracheal epithelial cells and its possible role in the regulation of cell proliferation. Exp Lung Res 1989; 15: 391–408
  • Eling T E, Henke D, Danilowicz R. Arachidonic acid metabolism in respiratory epithelial cells. Gen Pharmac 1988; 19: 313–316
  • Henke D H, Boucher R. Arachidonic acid (AA) metabolism by human airway epithelium. Am Rev Respir Dis 1989; 139: A409
  • Schafer A I, Takayama H, Farrel S, Gimbrone M A. Incorporation of platelet and leukocyte lipoxygenase metabolites by cultured vascular cells. Blood 1989; 67: 373–378
  • Stenson W F, Parker C W. Metabolism of arachidonic acid in ionophore-stimulated neutrophils. J Clin Invest 1979; 64: 1457–1465
  • Goetzl E J, Derian C, Valone F H. The extracellular and intracellular roles of hydroxy-eicosatetraenoic acids in the modulation of polymorphonuclear leukocyte and macrophage function. J Reticuloendothel Soc 1980; 28: 105s–110s
  • Gordon J A, Figard P H, Quinby G E, Spector A A. 5-HETE; uptake, distribution and metabolism in MDCK cells. Am J Physiol 1989; 256: Cl–C10, (Cell Physiol 25)
  • Coleman D L, Tuet I K, Widdicombe J H. Electrical properties of dog tracheal epithelial cells grown in monolayer culture. Am J Physiol 1984; 246: C355–C359
  • Wu R, Smith D. Continuous multiplication of rabbit tracheal epithelial cells in a defined hormone-supplemented media. In Vitro 1982; 18: 800–812
  • Wu R. In vitro differentiation of airway epithelial cells. In vitro Models of Respiratory Epithelium, L J Schiff. CRC Press, Boca Raton 1986; 1–26
  • Gabridge M G, Hoglund L E. Mycoplasma pneumoniae infection of intact guinea pig trachea cultures in a unique matrix-embedded perfusion system. In Vitro 1981; 17: 847–858
  • Powell W S. Rapid extraction of arachidonic acid metabolites from biological samples using octadocylsilyl silica. Methods in Enzymology, W Lands, W Smith. Academic Press, New York 1982; vol. 86: 467–477
  • Neufeld E J, Majerus P W. Arachidonate release and phosphatidic acid turnover in stimulated human platelets. J Biol Chem 1984; 258: 2461–2467
  • Kates M. Techniques in Lipodology2nd edition. Elsevier, Amsterdam 1986; 396
  • Bach M K, Brashler J R, White G J, Galli S J. Experiments on the metabolic actions of Piriprost (U-60257), an inhibitor of leukotriene formation in cloned mouse mast cells and in rat basophilic leukema cells. Biochem Pharmacol 1987; 86: 1461–1466
  • Revtyak G E, Johnson A R, Campbell W B. Cultured bovine coronary arterial endothelial cells synthesize HETEs and prostacyclin. Am J Physiol 1988; 254: C8–C19
  • Charo I F, Shak S, Karasek M A, Davison P M, Goldstein I M. Prostaglandin is not a major metabolite of arachidonic acid in cultured endothelial cells from human foreskin microvessels. J Clin Invest 1984; 74: 914–919
  • Kent R S, Diedrich S L, Whorton A R. Regulation of vascular prostaglandin synthesis by metabolites of arachidonic acid in perfused rabbit aorta. J Clin Invest 1983; 72: 455–465
  • Sheng W Y, Lysz T A, Wyche A, Needleman P. Kinetic comparison and regulation of the cascade of microsomal enzymes involved in arachidonate and endo-peroxide metabolism. J Biol Chem 1983; 258: 2188–2192
  • Sraer J, Rigaud M, Bens M, Rabinovitch H, Ardaillou R. Metabolism of arachi-donic acid via the lipoxygenase pathway in human and murine glomeruli. J Biol Chem 1983; 258: 4325–4330
  • Holmsen H, Nordvi B. Uptake and release of eicosanoid precursors from phospholipids and other pools: Platelets. Handbook of Eicosa-noids: Prostaglandins and Related Lipids, A L Willis. CRC Press, Boca Raton 1987; 119–132
  • Capriotti A M, Furth E E, Arrasmith M E, Laposata M. Arachidonate released upon agonist stimulation preferentially originates from arachidonate most recently incorporated into nuclear membrane phospholipids. J Biol Chem 1988; 263: 10029–10034
  • O'Flaherty J T, Wykle R L, Redman J, Samuel M, Thomas M. Metabolism of 5-hydroxyeicosatetraenoate by human neurophils: Production of a novel w-oxidized derivative. J Immunol 1986; 137: 3277–33283
  • Alpert S E, Dennery P A, Roberts W E. Rabbit tracheal epithelial cells in culture are deficient in arachidonic acid relative to acutely recovered epithelium. Am Rev Respir Dis 1988; 137: A429
  • Willis A L. The Eicosanoids: An introduction and an overview. Handbook of Eicosanoids: Prostaglandins and Related Lipids, A L Willis. CRC Press, Boca Raton 1987; 3–46
  • Alpert S E, Kramer C M. Effect of fatty acid profiles and arachidonic acid content on basal and CA2+ ionophore induced eicosanoid metabolism in cultured rabbit and human tracheal epithelial cells. Am Rev Respir Dis 1989; 139: A409
  • Bryant R W, Hwang D H. Development of a radioimmunoassay for 15-HETE and its application to 15-HETE production by reticulocytes. Prostaglandins 1983; 26: 375–386
  • Lam B K, Lee C Y, Wong P YK. Phospholipase A2 releases lipoxins and leuko-trienes from endogenous sources. Ann New York Acad Sci 1988; 524: 27–34
  • Maclouf J, Fruteau de Laclos B, Borgeat P. Stimulation of leukotriene biosynthesis in human blood leukocytes by platelet-derived 12-hydroperoxyeico-satetraenoic acid. Proc Natl Acad Sci USA 1982; 79: 6042–6046
  • Stenson W F, Parker C W. Monohydroxyeicosatetraenoic acids (HETEs) induce degranulation of human neutrophils. J Immunol 1980; 124: 2100–2104
  • Strenson W F, Parker C W, Sullivan T J. Augmentation of IgE-mediated release of histamine by 5-hydroxyeicosatetraenoic acid and 12-hydroxyeicosatetraenoic acid. Biochem Biophys Res Commun 1980; 96: 1045–1052

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