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Original Article

Suppression and Recovery of the Alveolar Macrophage Phagocytic System during Continuous Exposure to 0.5 ppm Ozone

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Pages 547-558 | Received 19 Feb 1990, Accepted 25 Apr 1990, Published online: 02 Jul 2009

References

  • Menzel D B. Ozone: An overview of its toxicity in man and animals. J Toxicol Environ Health 1984; 13: 183–204
  • Mehlman M A, Borek C. Toxicity and biochemical mechanisms of ozone. Environ Res 1987; 42: 36–53
  • Gardner D E. Oxidant-induced enhanced sensitivity to infection in animal models and their extrapolations to man. J Toxicol Environ Health 1984; 13: 423–439
  • Boorman G A, Schwartz L W, Wilson F D. In vitro macrophage colony formation by free lung cells during pulmonary injury. J Reticuloendothel Soc 1979; 26: 867–872
  • Evans M J, Johnson L V, Stephens R J, Freeman G. Cell renewal in the lungs of rats exposed to low levels of ozone. Exp Mol Pathol 1976; 24: 70–83
  • Nikula K J, Wilson D W, Dungworth D L, Plopper C G. In vitro evidence of cellular adaptation to ozone toxicity in the rat trachea. Toxicol Appl Pharmacol 1988; 93: 394–402
  • Driscoll K E, Vollmuth T A, Schlesinger R B. Acute and subchronic ozone inhalation in the rabbit: response of the alveolar macrophages. J Toxicol Environ Health 1987; 21: 27–43
  • Selgrade M K, Illing J W, Starnes D M, Stead A G, Menache M G, Stevens M A. Evaluation of effects of ozone exposure on influenza infection in mice using several indicators of susceptibility. Fundamental Appl Toxicol 1988; 11: 169–180
  • Goldstein E, Tyler W S, Hoeprich P D, Eagle C. Ozone and the antibacterial defense mechanisms of the murine lung. Arch Intern Med 1971; 127: 1099–1102
  • Goldstein E, Bartlema H C, van der Ploeg M, van Duijn P, van der Stap J, Lippert W. Effects of ozone on lysosomal enzymes of alveolar macrophages engaged in phagocytosis and killing of inhaled Staphylococcus aureus. J Infect Dis 1978; 138: 299–311
  • Green G M, Jakab G J, Low R B, Davis G S. Defense mechanisms of the respiratory membrane. Am Rev Respir Dis 1977; 115: 479–514
  • Goldstein E, Lippert W, Warshauer D. Pulmonary alveolar macrophage: defender against bacterial infection of the lung. J Clin Invest 1974; 54: 519–528
  • Pierce A K, Reynolds R C, Harris G D. Leukocytic response to inhaled bacteria. Am Rev Respir Dis 1977; 116: 679–684
  • Rehm S R, Gross G N, Hart D A, Pierce A K. Animal model of neutropenia suitable for the study of dual phagocyte system. Infect Immunol 1979; 25: 299–303
  • Rehm S R, Gross G N, Pierce A K. Early bacterial clearance from murine lungs: species dependent phagocytic response. J Clin Invest 1980; 66: 194–199
  • Hemenway D R, Mc Askill S M. Design, development and test results of a horizontal flow inhalation toxicology facility. Am Ind Hyg Assoc J 1982; 43: 874–879
  • Jakab G J, Green G M. The effect of Sendai virus infection on bactericidal and transport mechanisms of the murine lung. J Clin Invest 1972; 51: 1989–1998
  • Ruppert D, Jakab G J, Sylwester L L, Green G M. Sources of variance in the measurement of intrapulmonary killing of bacteria. J Lab Clin Invest 1976; 87: 544–558
  • Warr G A, Jakab G J, Hearst J E. Alterations in lung macrophage immune receptor(s) activity associated with viral pneumonia. J Reticuloendothel Soc 1979; 26: 357–366
  • Mochitate K, Miura T. Metabolic enhancement and increase of alveolar macrophages induced by ozone. Environ Res 1989; 49: 79–92
  • Wright E S, White D M, Brady A N, Li L C, D'Arcy J B, Smiler K L. DNA synthesis in pulmonary alveolar macrophages and type II cells: effects of ozone exposure and treatment with alpha-difluoromethylornithine. J Toxicol Environ Health 1987; 21: 15–26
  • Hotchkiss J A, Harkema J R, Kirkpatrick D T, Henderson R F. Response of rat alveolar macrophages to ozone: quantitative assessment of population size, morphology and proliferation following acute exposure. Exp Lung Res 1988; 15: 1–16
  • Huber G L, Mason R J, La Force M, Spencer N, Gardner D E, Coffin D L. Alterations in the lung following the administration of ozone. Arch Intern Med 1971; 128: 81–87
  • Astry C A, Warr G A, Jakab G J. Impairment of polymorphonuclear leukocyte immigration as a mechanism of alcohol-induced suppression of pulmonary antibacterial defenses. Am Rev Respir Dis 1983; 128: 113–117
  • Rylander R, Snella M C, Garcia I. Pulmonary cell response patterns after exposure to airborne bacteria. Scan J Respir Dis 1975; 59: 195–200
  • Jakab G J. Modulation of pulmonary defense mechanisms by acute exposures to nitrogen dioxide. Environ Res 1987; 42: 215–228
  • Aranyi C, Vana S C, Thomas P T, Bradof J N, Fenters J D, Graham J A, Miller F J. Effects of subchronic exposure to mixtures of O3, SO2, and (NH4)2SO4 on host defenses of mice. J Toxicol Environ Health 1983; 12: 55–71

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