Pulmonary Veins and Bronchial Vessels Undergo Remodeling in Sustained Pulmonary Hypertension Induced by Continuous Air Embolization Into Sheep

References

• Meyrick B, Reid L. Pulmonary hypertension: anatomic and physiologic correlates. Clin Chest Med 1993; 4: 199–217
   Google Scholar
• Chazova I, Loyd J E, Zhdanov V S, Newman J H, Belenkov Y, Meyrick B. Pulmonary artery adventitial changes and venous involvement in primary pulmonary hypertension. Am J Pathol 1995; 146: 389–397
   PubMed Web of Science ®Google Scholar
• Marchand P, Gilroy J C, Wilson VH. An anatomical study of the bronchial vascular system and its variations in disease. Thorax 1950; 5: 207–221
   PubMed Web of Science ®Google Scholar
• Wagenvoort C A, Wagenvoort N. Pulmonary venous changes in chronic hypoxia. Virchows Arch Pathol Anat 1976; 372: 51–56
   PubMedGoogle Scholar
• Dingemans K P, Wagenvoort CA. Pulmonary arteries and veins in experimental hypoxia. Am J Pathol 1978; 93: 353–368
   PubMed Web of Science ®Google Scholar
• Hu L M, Jones R. Injury and remodelling of pulmonary veins by high oxygen: a morphometric study. Am J Pathol 1989; 134: 253–262
   PubMed Web of Science ®Google Scholar
• Wilson D W, Segall H J, Dunston SK. Progressive inflammatory and structural changes in the pulmonary vasculature of monocrotaline-treated rats. Microvasc Res 1989; 38: 57–80
   PubMed Web of Science ®Google Scholar
• Atwal O S, Persofsky MS. Ultrastructural changes in intraacinar pulmonary veins: relationship to 3-methylindole-induced acute pulmonary edema and pulmonary arterial changes in cattle. Am J Pathol 1984; 114: 472–486
   PubMed Web of Science ®Google Scholar
• Wagenvoort C A, Wagenvoort N, Dijk HJ. Effect of fulvine on pulmonary arteries and veins of the rat. Thorax 1975; 9: 522–529
   Google Scholar
• Schraufnagal DE. Monocrotaline-induced angiogenesis. Differences in the bronchial and pulmonary vasculature. Am J Pathol 1990; 137: 1083–1090
   PubMed Web of Science ®Google Scholar
• Perkett E A, Brigham K L, Meyrick B. Continuous air embolization into sheep causes sustained pulmonary hypertension and increased pulmonary vasoreactivity. Am J Pathol 1988; 132: 444–454
   PubMed Web of Science ®Google Scholar
• Perkett E A, Davidson J M, Meyrick B. Sequence of structural changes and elastin peptide release during vascular remodelling in sheep with chronic pulmonary hypertension induced by air embolization. Am J Pathol 1991; 139: 1319–1332
   PubMed Web of Science ®Google Scholar
• Charan N B, Turk G M, Czartolomny J, Andreazuk T. Systemic arterial blood supply to the trachea and lung in sheep. J Appl Physiol 1987; 62: 2283–2287
   PubMed Web of Science ®Google Scholar
• Perkett E A, Brigham K L, Meyrick B. Granulocyte depletion attenuates sustained pulmonary hypertension and increased pulmonary vasoreactivity caused by continuous air embolization in sheep. Am Rev Respir Dis 1990; 141: 456–465
   PubMed Web of Science ®Google Scholar
• Meyrick B, Reid L. The effect of continued hypoxia on rat pulmonary arterial circulation: an ultrastructural study. Lab Invest 1978; 38: 188–200
   PubMed Web of Science ®Google Scholar
• Jones R. Ultrastructural analysis of contractile cell development in lung microvessels in hyperoxic pulmonary hypertension. Am J Pathol 1992; 141: 1491–1505
   PubMed Web of Science ®Google Scholar
• Meyrick B, Reid L. Hypoxia and incorporation of 3H-thymidine by cells of rat pulmonary arteries and alveolar wall. Am J Pathol 1979; 96: 51–70
   PubMed Web of Science ®Google Scholar
• Meyrick B, Reid L. Crotalaria-induced pulmonary hypertension: uptake of 3H-thymidine by the cells of the pulmonary circulation and alveolar walls. Am J Pathol 1982; 106: 84–94
   PubMed Web of Science ®Google Scholar
• Hislop A, Reid L. New findings in pulmonary arteries of rats with hypoxia-induced pulmonary hypertension. Br J Exp Pathol 1976; 57: 542–554
   PubMed Web of Science ®Google Scholar
• Meyrick B, Reid L. Development of arterial changes in rats fed by Crotalaria spectabilis. Am J Pathol 1979; 94: 37–50
   PubMed Web of Science ®Google Scholar
• Perkett E A, Pelton R W, Meyrick B, Gold L, Miller DA. Expression of transforming growth factor-β mRNAs and proteins in pulmonary vascular remodelling in the sheep air embolization model of pulmonary hypertension. Am J Respir Cell Mol Biol 1994; 11: 16–24
   PubMed Web of Science ®Google Scholar
• Perkett E A, Badesch D B, Roessler M K, Stenmark K R, Meyrick BO. Insulin-like growth factor-I and pulmonary hypertension induced by continuous air embolization in sheep. Am J Respir Cell Mol Biol 1992; 6: 82–87
   PubMed Web of Science ®Google Scholar
• Gibbons G H, Dzau VJ. The emerging concept of vascular remodeling. N Engl J Med 1994; 330: 1431–1438
   PubMed Web of Science ®Google Scholar
• Stewart D J, Levy R D, Cernacek P, Langleben D. Increased plasma endothelin-1 in pulmonary hypertension: marker or mediator of disease. Ann Int Med 1991; 114: 464–469
   PubMed Web of Science ®Google Scholar
• Giaid A, Yanagisawa M, Langleben D, et al. Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. N Engl J Med 1993; 328: 1732–1739
   PubMed Web of Science ®Google Scholar
• Li H, Chen S J, Chen Y F, Meng Q C, Durand J, Oparil S, Elton TS. Enhanced endothelin-1 and endothelin receptor gene expression in chronic hypoxia. J Appl Physiol 1994; 77: 1451–1459
   PubMed Web of Science ®Google Scholar
• Miyauchi T, Yorikane S, Sakurai T, et al. Contribution of endogenous endothelin-1 to the progression of cardiopulmonary alterations in rats with monocrotaline-induced pulmonary hypertension. Circ Res 1993; 73: 887–897
   PubMed Web of Science ®Google Scholar
• Tchekneva E, Quertermous T, Meyrick B. Differential expression of the endothelin-1 (ET-1) gene in ovine lung and pulmonary artery with air-induced pulmonary hypertension. Am J Respir Crit Care Med 1996; 153: A191
   PubMedGoogle Scholar
• Pearse D B, Wagner EM. Role of the bronchial circulation in ischemia—reperfusion lung injury. J Appl Physiol 1994; 76: 259–265
   PubMed Web of Science ®Google Scholar
• Michel R R, Hakim TS. Increased resistance in postobstructive pulmonary vasculopathy: structure-function relationships. J Appl Physiol 1991; 71: 601–610
   PubMed Web of Science ®Google Scholar
• Thompson A B, Teschler H, Rennard SI. Pathogenesis, evaluation, and therapy for massive hemoptysis. Clin Chest Med 1992; 13: 68–82
   Google Scholar
• Ohmichi M, Tagaki S, Nomura N, Tsunematsu K, Suzuki A. Endobronchial changes in chronic pulmonary venous hypertension. Chest 1988; 94: 1127–1132
   PubMed Web of Science ®Google Scholar
• Schraufnagel D E, Arzouman D A, Sekosan M, Ho YK. The effect of transforming growth factor-alpha on airway angiogenesis. J Thorac Cardiovasc Surg 1992; 104: 1582–1588
   PubMed Web of Science ®Google Scholar
• Albertine K H, Weiner-Kronish J P, Koike K, Staub NC. Quantification of damage by air embolization to lung microvessels in anesthetized sheep. J Appl Physiol 1984; 57: 1360–1368
   PubMed Web of Science ®Google Scholar