37
Views
47
CrossRef citations to date
0
Altmetric
Original Article

Additional Evidence That the K-ras Protooncogene is a Candidate for the Major Mouse Pulmonary Adenoma Susceptibility (Pas-1) Gene

, , , , , , , , , & show all
Pages 481-497 | Received 10 Feb 1998, Accepted 10 Feb 1998, Published online: 02 Jul 2009

References

  • Bailey D W. Recombinant inbred strains and bilinear congenic strains. The Mouse in Biomedical Research, H L Foster, J D Small, J G Fox. Academic, New York 1981; 223–234
  • Taylor B A. Recombinant-inbred strains: use in gene mapping. Origins of Inbred Mice, H C Morse. Academic, New York 1978; 423–440
  • Nesbitt M N, Skamene E. Recombinant inbred mouse strains derived from A/J and C57BL/6J mice: a tool for the study of genetic mechanisms in host resistance to the infection and malignancy. J Leukocyte Biol. 1984; 36: 357–364
  • Marshall J D, Mu J L, Cheah Y C, Nesbitt M N, Frankel W N, Paigen B. The A X B and B X A set of recombinant inbred mouse strains. Mamm Genome. 1992; 3: 669–680
  • Heston W E. Genetic analysis of susceptibility to induced pulmonary tumors in mice. J Natl Cancer Inst. 1942; 3: 69–78
  • Bos J L. Ras oncogene in human cancer: a review. Cancer Res. 1989; 49: 4682–4689
  • Stanley L A. Molecular aspects of chemical carcinogenesis: the roles of oncogenes and tumor suppressor genes. Toxicology. 1995; 96: 173–194
  • Johnson G L, Vaillancourt R R. Sequential protein kinase reactions controlling cell division and differentiation. Curr Opin Cell Biol. 1994; 6: 230–238
  • Arends M G, McGregor A H, Toft A J. Susceptibility to apoptosis is differentially regulated by c-myc and mutated Ha-ras oncogenes and is associated with endonuclease availability. Br J Cancer. 1993; 68: 1127–1133
  • Bremmer R, Balmain A. Genetic changes in skin tumor progression: correlation between presence of a mutant ras gene and loss of heterozygosity on mouse chromosome 7. Cell. 1990; 61: 401–417
  • You M, Candrian U, Maronpot R R, Stoner G D, Anderson M W. Activation of the Ki-ras protoonocogene in spontaneously occurring and chemically induced lung tumors of the strain A mouse. Proc Natl Acad Sci USA. 1989; 86: 3070–3074
  • Reynolds S H, Anna C K, Brown K C, et al. Activated protooncogenes in human lung tumors from smokers. Proc Natl Acad Sci USA. 1991; 88: 1085–1089
  • Rodenhuis S, Slebos R J. Clinical significance of ras oncogene activation in human lung cancer. Cancer Res. 1992; 52: 2665s–2669s
  • Stowers S J, Glover P L, Reynolds S H, Boone L R, Maronpot R R, Anderson M W. Activation of the K-ras protooncogene in lung tumors from rats and mice chronically exposed to tetranitromethane. Cancer Res. 1987; 47: 3212–3219
  • Oreffo V I, Lin H W, Gumerlock P H, Kraegel S A, Witschi H. Mutational analysis of a dominant oncogene (c-Ki-ras-2) and a tumor suppressor gene (p53) in hamster lung tumorigenesis. Mol Carcinog. 1992; 6: 199–202
  • Belinsky S A, Devereux T R, Foley J F, Maronpot R R, Anderson M W. Role of the alveolar type II cell in the development and progression of pulmonary tumors induced by 4- (methylnitrosamino)-1- (3-pyridyl)-1-butanone in the A/J mouse. Cancer Res. 1992; 52: 3164–3173
  • Horio Y, Schrump D S, Chen A, Rice P, Malkinson A M, Roth J A. K-ras and p53 mutations are early and late events, respectively, in urethane-induced pulmonary carcinogenesis in A/J mice. Mol Carcinog. 1996; 17: 217–223
  • Ryan J, Barker P E, Nesbitt M N, Ruddle F H. KRAS2 as a genetic marker for lung tumor susceptibility in inbred mice. J Natl Cancer Inst. 1987; 79: 1351–1357
  • You M, Wang Y, Stoner G D, et al. Parental bias of Ki-ras oncogenes detected in lung tumors from mouse hybrids. Proc Natl Acad Sci USA. 1992; 89: 5804–5808
  • Chen B, Johanson L, Wiest J S, Anderson M W, You M. The second intron of the K-ras gene contains regulatory elements associated with mouse lung tumor susceptibility. Proc Natl Acad Sci USA. 1994; 91: 1589–1593
  • Malkinson A M, You M. The intronic structure of cancer-related genes regulates susceptibility to cancer. Mol Carcinog. 1994; 10: 61–65
  • Chen B, You L, Wang Y, Stoner G D, You M. Allele-specific activation and expression of the K-ras gene in hybrid mouse lung tumors induced by chemical carcinogens. Carcinogenesis. 1994; 9: 2031–2035
  • Chen B, Wang Y, You M. Characterization of two protein binding sites in the second intron of the mouse K-ras gene. Proc Am Assoc Cancer Res. 1995; 36: 3365
  • Devereux T R, Belinsky S A, Maronpot R R, et al. Comparison of pulmonary O6-methylguanine DNA adduct levels and Ki-ras activation in lung tumors from resistant and susceptible mouse strains. Mol Carcinog. 1993; 8: 177–185
  • Malkinson A M, Nesbitt M N, Skamene E. Susceptibility to urethane-induced pulmonary adenomas between A/J and C57BL/6J mice: use of A × B and B × A recombinant inbred lines indicating a three-locus genetic model. J Natl Cancer Inst. 1985; 75: 971–974
  • Thaete L G, Nesbitt M N, Malkinson A M. Lung tumor structure among inbred strains of mice: the pulmonary adenoma histologic type (Paht) genes. Cancer Lett. 1991; 61: 15–20
  • Naggert J K, Svenson K I, Lin L, et al. An additional 137 SSLP markers typed for the AxB and BxA recombinant inbred mouse strains. Mamm Genome. 1997; 8: 209–211
  • Manly K F. A macintosh program for storage and analysis of experimental genetic mapping data. Mamm Genome. 1993; 4: 303–313
  • Orita M, Iwahana H, Kanazawa H, Hayashi K, Sekiya T. Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proc Natl Acad Sci USA. 1989; 86: 2766–2770
  • Orita M, Suzuki Y, Sekiya T, Hayashi K. Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction. Genomics. 1989; 5: 874–879
  • Lander E, Leonid K. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nature Genet. 1995; 11: 241–247
  • Gariboldi M, Manenti G, Canzian F, et al. A major susceptibility locus to murine lung carcinogenesis maps on chromosome 6. Nature Genet. 1993; 3: 132–136
  • Devereux T R, Wiseman R W, Kaplan N, et al. Assignment of a locus for mouse lung tumor susceptibility to proximal chromosome 19. Mamm Genome. 1994; 5: 749–755
  • Festing M FW, Yang A, Malkinson A M. At least four genes and sex are associated with susceptibility to urethane-induced mouse pulmonary adenomas in mice. Genet Res. 1994; 64: 99–106
  • Matzinger S A, Chen B, Wang Y, et al. Tissue-specific expression of the K-ras allele from the A/J parent in (A/J × TSG-p53) F1 mice. Gene. 1997; 188: 261–269
  • Zhang Z Q, Wang Y, Wang Yian You M. K-ras promoter sequence variations among inbred mouse strains contribute to the differential expression of K-ras in hybrid mice. Proc Am Assoc Cancer Res. 1997; 38: 3903
  • Chen B, Wang Y, Zhang Z Q, Wang Yian You M. Characterization of a novel enhancer elements located in the second intron of the K-ras gene: implications for allele-specific expression of K-ras in mouse hybrids. Proc Am Assoc Cancer Res. 1995; 36: 3345
  • Justice M J, Siracusa L D, Gilbert D J, et al. A genetic linkage map of mouse chromosome 10: localization of eighteen molecular markers using a single interspecific backcross. Genetics. 1990; 125: 855–866
  • Sunada Y, Bernier S M, Kozak C A, Yamada Y, Campbell K P. Deficiency of merosin in dystrophic dy mice and genetic linkage of laminin M chain gene to dy locus. J Biol Chem. 1994; 269: 13729–13732
  • Haefliger J A, Bruzzone R, Jenkins N A, Gilbert D J, Copeland N G, Paul D L. Four novel member of the connexin family of gap junction proteins: molecular cloning, expression, and chromosome mapping. J Biol Chem. 1992; 267: 2057–2064
  • Fijneman R J, Oomen L C, Snoek M, Demant P. A susceptibility gene for alveolar lung tumors in the mouse maps between Hsp70.3 and G7 within the H-2 complex. Immunogenetics. 1995; 41: 106–109
  • Rochelle J M, Watson M L, Oakly R J, Seldin M F. A linkage map of mouse chromosome 19: definition of comparative mapping relationship with human chromosome 10 and 11 including the MEN 1 locus. Genomics. 1992; 14: 26–31
  • Watanabe-Kukunnaga R, Brannan C I, Copeland N G, Jenkins N A, Nagata S. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 1992; 356: 314–317
  • Wilkie T M, Scherle P A, Strathmann M P, Slepak V Z, Simon M I. Characterization of G-protein alpha subunits in the Gq class: expression in murine tissues and in stromal and hematopoietic cell lines. Proc Natl Acad Sci USA. 1991; 88: 10049–10053
  • Wilkie T M, Gilbert D J, Olsen A S, et al. Evolution of the mammalian G protein alpha subunit multigene family. Nature Genet. 1992; 1: 85–91

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.