432
Views
5
CrossRef citations to date
0
Altmetric
Basic Research

Analysis of Mitochondrial Network Morphology in Cultured Myoblasts from Patients with Mitochondrial Disorders

, MSc, PhD, , MSc, , MSc, PhD, , MSc, PhD, , MSc, PhD, , MD, PhD, , MD, PhD, , MD, PhD, , MSc, PhD & , MD, PhD show all
Pages 340-350 | Received 30 Mar 2015, Accepted 19 May 2015, Published online: 27 Jul 2015

References

  • Dumoulin R, Mandon G, Collombet JM, et al.Human cultured myoblasts: A model for the diagnosis of mitochondrial diseases. J Inherit Metab Dis 1993;16: 545–7
  • Mauro A.Satellite cell of skeletal muscle fibers. J BiophysBiochemCytol 1961;9: 493–5
  • Schultz E, Jaryszak DL, Valliere CR.Response of satellite cells to focal skeletal muscle injury.Muscle Nerve 1985;8: 217–22
  • Barbieri E, Battistelli M, Casadei L, et al.Morphofunctional and biochemical approaches for studying mitochondrial changes during myoblasts differentiation. J Aging Res 2011;2011: 845379
  • Kim YK, Ha HH, Lee JS, et al. Control of muscle differentiation by a mitochondria-targeted fluorophore. J Am Chem Soc 2010;132: 576–9
  • Pejznochova M, Tesarova M, Hansikova H, et al. Mitochondrial DNA content and expression of genes involved in mtDNA transcription, regulation and maintenance during human fetal development. Mitochondrion 2010;10: 321–9
  • Lewandowska E, Schmidt-Sidor B, Mierzewska H, et al.Ultrastructural study of mother and daughter muscle changes with mitochondrial encephalomyopathy. Folia Neuropathol 2001;39: 271–6
  • Lewandowska E, Wierzba-Bobrowicz T, Rola R, et al. Pathology of skeletal muscle cells in adult-onset glycogenosis type II (Pompe disease): Ultrastructural study. Folia Neuropathol 2008;46: 123–33
  • Fidzianska A, Glinka Z. Did giant mitochondria delay muscle maturation? An uncommon congenital myopathy. Muscle Nerve 2012;46: 125–9
  • Coleman R, Silbermann M, Gershon D, Reznick AZ. Giant mitochondria in the myocardium of aging and endurance-trained mice. Gerontology 1987;33: 34–9
  • Beregi E, Regius O, Huttl T, Gobl Z. Age-related changes in the skeletal muscle cells. Z Gerontol 1988;21: 83–6
  • Terman A, Dalen H, Eaton JW, et al. Mitochondrial recycling and aging of cardiac myocytes: The role of autophagocytosis. ExpGerontol 2003;38: 863–76
  • Duguez S, Sabido O, Freyssenet D. Mitochondrial-dependent regulation of myoblast proliferation. Exp Cell Res 2004;299: 27–35
  • Wagatsuma A, Sakuma K. Mitochondria as a potential regulator of myogenesis. Scientific World J 2013;2013: 593267
  • Rusanen H, Annunen J, Yla-Outinen H, et al. Cytoskeletal structure of myoblasts with the mitochondrial DNA 3243A→G mutation and of osteosarcoma cells with respiratory chain deficiency. Cell Motil Cytoskeleton 2002;53: 231–8
  • Richler C, Yaffe D. The in vitro cultivation and differentiation capacities of myogenic cell lines. Dev Biol 1970;23: 1–22
  • Kaufman SJ, Foster RF. Replicating myoblasts express a muscle-specific phenotype. Proc Natl Acad Sci USA 1988;85: 9606–10
  • Hicks D, Lampe AK, Laval SH, et al. Cyclosporine A treatment for Ullrich congenital muscular dystrophy: A cellular study of mitochondrial dysfunction and its rescue. Brain 2009;132: 147–55
  • Luft JH. Permanganate: A new fixative for electron microscopy. J Biophys Biochem Cytol 1956;2: 799–802
  • Brantova O, Tesarova M, Hansikova H, et al. Ultrastructural changes of mitochondria in the cultivated skin fibroblasts of patients with point mutations in mitochondrial DNA. Ultrastruct Pathol 2006;30: 239–45
  • Spinazzi M, Cazzola S, Bortolozzi M, et al. A novel deletion in the GTPase domain of OPA1 causes defects in mitochondrial morphology and distribution, but not in function. Hum Mol Genet 2008;17: 3291–302
  • Elo JM, Yadavalli SS, Euro L, et al. Mitochondrial phenylalanyl-tRNAsynthetase mutations underlie fatal infantile Alpers encephalopathy. Hum Mol Genet 2012;21: 4521–9
  • Koopman WJ, Visch HJ, Verkaart S, et al. Mitochondrial network complexity and pathological decrease in complex I activity are tightly correlated in isolated human complex I deficiency. Am J Physiol Cell Physiol 2005;289: C881–90
  • Koopman WJ, Verkaart S, Visch HJ, et al. Human NADH: Ubiquinone oxidoreductase deficiency: Radical changes in mitochondrial morphology? Am J Physiol Cell Physiol 2007;293: C22–9
  • De Vos KJ, Sheetz MP. Visualization and quantification of mitochondrial dynamics in living animal cells. Methods Cell Biol 2007;80: 627–82
  • Plecita-Hlavata L, Lessard M, Santorova J, et al. Mitochondrial oxidative phosphorylation and energetic status are reflected by morphology of mitochondrial network in INS-1 E and HEP-G2 cells viewed by 4Pi microscopy. Biochim Biophys Acta 2008;1777: 834–46
  • Makino A, Suarez J, Gawlowski T, et al. Regulation of mitochondrial morphology and function by O-GlcNAcylation in neonatal cardiac myocytes. Am J Physiol 2011;300: R1296–302
  • Nikolaisen J, Nilsson LI, Pettersen IK, et al. Automated quantification and integrative analysis of 2D and 3D mitochondrial shape and network properties. PloS One 2014;9: e101365
  • Aure K, Fayet G, Leroy JP, et al. Apoptosis in mitochondrial myopathies is linked to mitochondrial proliferation. Brain 2006;129: 1249–59
  • Altamirano J, Miquel R, Katoonizadeh A, et al. A histologic scoring system for prognosis of patients with alcoholic hepatitis. Gastroenterology 2014;146: 1231–1239.e1231–1236
  • Arismendi-Morillo G. Electron microscopy morphology of the mitochondrial network in human cancer. Int J Biochem Cell Biol 2009;41: 2062–8
  • Pronicki M, Matyja E, Piekutowska-Abramczuk D, et al. Light and electron microscopy characteristics of the muscle of patients with SURF1 gene mutations associated with Leigh disease. J Clin Pathol 2008;61: 460–6
  • Horvath R, Kemp JP, Tuppen HA, et al. Molecular basis of infantile reversible cytochrome c oxidase deficiency myopathy. Brain 2009;132: 3165–74
  • Chow CW, Thorburn DR. Morphological correlates of mitochondrial dysfunction in children. Hum Reprod 2000;15: 68–78
  • John GB, Shang Y, Li L, et al. The mitochondrial inner membrane protein mitofilin controls cristae morphology. Mol Biol Cell 2005;16: 1543–54
  • Paumard P, Vaillier J, Coulary B, et al. The ATP synthase is involved in generating mitochondrial cristae morphology. EMBO J 2002;21: 221–30
  • Head BP, Zulaika M, Ryazantsev S, van der Bliek AM. A novel mitochondrial outer membrane protein, MOMA-1, that affects cristae morphology in Caenorhabditis elegans. Mol Biol Cell 2011;22: 831–41
  • Ghadially FN.Ultrastructural pathology of the cell and matrix,4th ed. Boston: Butterworth–Heinemann, 1997
  • Velours J, Dautant A, Salin B, et al. Mitochondrial F1F0-ATP synthase and organellar internal architecture. Int J Biochem Cell Biol 2009;41: 1783–9
  • Almsherqi Z, McLachlan CS, Tay SK, Deng Y. Chronic phenobarbital-induced mitochondrial pleomorphism in the rat liver. Toxicol Pathol 2007;35: 833–5
  • Skinnider LF, Ghadially FN. Chloramphenicol-induced mitochondrial and ultrastructural changes in hemopoietic cells. Arch Pathol Lab Med 1976;100: 601–5
  • Vays VB, Eldarov CM, Vangely IM, et al. Antioxidant SkQ1 delays sarcopenia-associated damage of mitochondrial ultrastructure. Aging (Albany NY) 2014;6: 140–8
  • Bereiter-Hahn J, Voth M.Dynamics of mitochondria in living cells: Shape changes, dislocations, fusion, and fission of mitochondria. Microsc Res Tech 1994;27: 198–219
  • Chen H, McCaffery JM, Chan DC. Mitochondrial fusion protects against neurodegeneration in the cerebellum. Cell 2007;130: 548–62
  • Vesela K, Hulkova H, Hansikova H, et al. Structural analysis of tissues affected by cytochrome C oxidase deficiency due to mutations in the SCO2 gene. APMIS 2008;116: 41–9
  • Wittig I, Meyer B, Heide H, et al. Assembly and oligomerization of human ATP synthase lacking mitochondrial subunits a and A6L. Biochim Biophys Acta 2010;1797: 1004–11
  • Collins TJ, Bootman MD. Mitochondria are morphologically heterogeneous within cells. J Exp Biol 2003;206: 1993–2000
  • Nishino I, Kobayashi O, Goto Y, et al. A new congenital muscular dystrophy with mitochondrial structural abnormalities. Muscle Nerve 1998;21: 40–7
  • Brantova O, Asfaw B, Sladkova J, et al. Ultrastructural and functional abnormalities of mitochondria in cultivated fibroblasts from alpha-mannosidosis patients. Biologia 2009;64: 394–401
  • Koenig MK. Presentation and diagnosis of mitochondrial disorders in children. Pediatr Neurol 2008;38: 305–13

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.