41
Views
8
CrossRef citations to date
0
Altmetric
Research Article

Effect of the solvent-non-solvent pairs on the surface morphology and release behaviour of ethylcellulose microcapsules prepared by non-solvent-addition phase separation method

, , &
Pages 297-308 | Received 13 Nov 1992, Accepted 19 Jan 1993, Published online: 27 Sep 2008

References

  • Benita S., Donbrow M. Effect of polyisobutylene on ethylcellulose-walled microcapsules: wall structure and thickness of salicylamide and theophylline microcapsules. Journal of Pharmaceutical Sciences 1982; 71: 205–210
  • Burrell H. Solubility parameter values. Polymer Handbook, J. Brandrup, E. H. Immergut. John Wiley & Sons, New York 1975; IV337–348
  • Donbrow M., Hoffman A., Benita S. Phase separation modulation and aggregation prevention: mechanism of the non-solvent addition method in the presence and absence of polyisobutylene as an additive. Journal of Microencapsulation 1990; 7: 1–15
  • El-Sayed A. A., Badawi A. A., Fouli A. M. Effect of solvent used in the preparation of solid dispersion and microcapsules on the dissolution of drugs. Pharmacutica Acta Helvetiae 1982; 57: 61–64
  • Gutcho M. H. Microcapsules and Microencapsulation Techniques. Noyes Data Corp., New Jersey 1976
  • Gutcho M. H. Microcapsules and Other Capsules, Advances Since 1975. Noyes Data Corp., New Jersey 1979
  • Iso M., Kando T., Omi S. A fundamental study of the microencapsulation procedure utilizing coacervation in a polystyrene-cyclohexane solution. Journal of Microencapsulation 1985; 2: 275–287
  • Kasai S., Koishi M. Studies on the preparation of ethylcellulose microcapsules containing magnesium aluminum hydroxide hydrate. Chemical and Pharmaceutical Bulletin 1977; 25: 314–320
  • Lin S. Y., Yang J. C., Jiang S. S. Studies on microencapsulation (I) micromeritic properties of theophylline microcapsules prepared by coacervation-phase separation method. Journal of the Taiwan Pharmaceutical Association 1985; 37: 1–9
  • Luu S. N., Carlier P. F., Delort P., Gazzola J., Llafont D. Determination of coating thickness of microcapsules and influence upon diffusion. Journal of Pharmaceutical Sciences 1973; 62: 452–455
  • Luzzi L. A. Microencapsulation. Journal of Pharmaceutical Sciences 1970; 59: 1367–1376
  • Merkle H. P., Speiser P. Preparation and in vitro evaluation of cellulose acetate phthalate coacervate microcapsules. Journal of Pharmaceutical Sciences 1973; 62: 1444–1448
  • Mulder M. Basic Principles of Membrane Technology. Kluwer, Taiwan 1991; 71–108
  • Nixon J. R. Preparation of microcapsules with possible pharmaceutical use. Endeavour 1985; 9: 123–128
  • Nixon J. R., Meleka M. R. The preparation and characterization of ethyl-cellulose-walled theophylline microcapsules. Journal of Microencapsulation 1984; 1: 53–64
  • Nixon J. R., Nimmannit U. Cellulose-walled microcapsules: 1. The effect of the solvent-nonsolvent proportions on the preparation of microcapsules from the system ethylcellulose–chloroform-ethane diol. Journal of Microencapsulation 1985; 2: 103–110
  • Powell T. C., Steinle M. E., Yoncoskie R. A. US Patent 1968; 3(415)758
  • Rayes Z., Park M. E. US Patent 1965; 3: 173–878
  • Robinson D. H. Ethylcellulose-solvent phase relationships relevant to coacervation microencapsulation processes. Drug Development and Industrial Pharmacy 1989; 15: 2597–2620
  • Rowe E. L., Township P., County K. US Patent 1967; 3: 336–155
  • Senjkovic R., Jalsenjak I. Apparent diffusion coefficient of sodium phenobar-bitone in ethylcellulose microcapsules: effects of capsule size. Journal of Pharmacy and Pharmacology 1981; 33: 279–282
  • Singh J., Robinson D. H. Controlled release captopril microcapsules: effect of ethylcellulose viscosity grade on the in vitro dissolution from microcapsules and tableted microcapsules. Journal of Microencapsulation 1990; 7: 67–76
  • Sparks R. E. Microencapsulation. Kirk-Othmer Encyclopedia of Chemical Technology, Vol. 15, H. F. Mark, D. F. Othmer, C. G. Overberger, G. T. Seaborg. John Wiley & Sons, New York 1981; 470–493
  • Suh K. W., Clarke D. H. Cohesive energy densities of polymers from turbidi-metric titrations. Journal of Polymer Science: Part A-1 1967; 5: 1671–1681
  • Suh K. W., Clarke D. H. Turbidimetric determinations of theta compositions. Journal of Applied Polymer Science 1968; 12: 1775–1779
  • Takenaka H., Kawashima Y., Lin S. Y. The effect of wall thickness and amount of hardening agent on the release characteristics of sulfamethoxazole microcapsules prepared by gelatin-acacia complex coacervation. Chemical and Pharmaceutical Bulletin 1979; 27: 3054–3060
  • Takenaka H., Kawashima Y., Lin S. Y. Micromeritic properties of sulfamethoxazole microcapsules prepared by gelatin-acacia coacervation. Journal of Pharmaceutical Sciences 1980; 69: 513–516
  • Wagner J. G. Interpretation of percent dissolved-time plots derived from in vitro testing of conventional tablets and capsules. Journal of Pharmaceutical Sciences 1969; 58: 1253–1257
  • Yalabik-Kas H. S. Microencapsulation and in vitro dissolution of oxazepam from ethylcellulose microcapsules. Drug Development and Industrial Pharmacy 1983; 9: 1047–1060

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.