Changes in intracellular pH induced by hyperthermia and hypoxia

References

• ALEXANDROV, N. N., SAVCHENKO, N. E., FRADKIN, S. Z., and ZAVRID, E. A., 1980, Application of Hyperthermia and Hyperglycemia in the Therapy of Malignant Tumors (Moscow: Medizina).
   Google Scholar
• BEN-HUR, E., ELKIND, M. M., and BRONK, B. V., 1974, Thermally enhanced radioresponse of cultured Chinese hamster cells: inhibition of repair of sublethal damage and enhancement of lethal damage. Radiation Research, 58,38–51.
   Google Scholar
• BICHEL, P., and OVERGAARD, J., 1977, Hyperthermic effect on exponential and plateau ascites tumour cells in vitro is dependent on environmental pH. Radiation Research, 70, 449^54.
   PubMedGoogle Scholar
• BOWDEN, G. T., and KASUNIC, M. D., 1981, Hyperthermic potentiation of the effects of a clinically significant X-ray dose on cell survival, DNA damage, and DNA repair. Radiation Research, 87,109–120.
   PubMed Web of Science ®Google Scholar
• CAVALIERE, R., CIOCATTO, E. C, GIOVANELLA, B. C, HEIDELBERGER, C, JOHNSON, R. O.,
   Google Scholar
• MARGOTTINI, M., MONDOVI, B., MORRICCA, G., and ROSSI-FANELLI, A., 1967, Selective heat sensitivity of cancer cells. Biochemical and clinical studies. Cancer, 20,1351–1381.
   PubMedGoogle Scholar
• DEWEY, W. C, HOPWOOD, L. E., SAPARATO, S. A., and GERWECK, L. S., 1977, Cellular responses to combination of hyperthermia and radiation. Radiology, 123,463–474.
   PubMed Web of Science ®Google Scholar
• EPIFANOVA, O. J., TERSKIKH, V. V., and POLUNOVKSY, V. A., 1983, Resting Cells (Moscow: Nauka).
   Google Scholar
• FREEMAN, M. L., HALAHAN, E. V., HIGHFIELD, D. P., RAAPHORST, G. P., SPIRO, I. J., and DEWEY, W. C, 1981, The effect of pH on hyperthermic and X-ray induced cell killing. InternationalJournal of Radiation, Oncology, Biology, Physics, 7, 211–216.
   PubMed Web of Science ®Google Scholar
• GERWECK, L. E., NYGAARD, T. G., and BURLETT, M., 1979, Response of cells to hyperthermia under acute and chronic hypoxic conditions. Cancer Research, 39, 966–972.
   PubMed Web of Science ®Google Scholar
• HAVEMAN, J., 1979, The pH of the cytoplasm as an important factor in the survival of in vitro cultured malignant cells after hyperthermia. Effects of carbonyl cyanide-3-chlorophenyl-hydrazone. European Journal of 'Cancer, 15,1281–1288.
   PubMed Web of Science ®Google Scholar
• HAVEMAN, J., 1980, The influence of pH on the survival after X-irradiation of cultured malignant cells. Effects of carbonylcyanide-3-chlorphenylhydrazone. International Journal of Radiation Biology, 37, 201–205.
   Google Scholar
• HAVEMAN, J., 1983, Influence of pH and thermotolerance on the enhancement of X-ray induced �nactivation of cultured mammalian cells by hyperthermia. International Journal of Radiation Biology, 43, 281–289.
   Web of Science ®Google Scholar
• HOFER, K. G., CHOPPIN, D. A., and HOFER, M. G., 1976, Effect of hyperthermia on the radio-sensitivity of normal and malignant cells in mice. Cancer, 38, 279–287.
   PubMedGoogle Scholar
• HOFER, K. G., HOFER, M. G., IERACITAMO, J., and MCLAUGHLIN, W. H., 1977, Radiosensitization of hypoxic tumour cells by simultaneous administration of hyperthermia and nitro- imidazoles. Radiation Research, 70, 362–377.
   PubMed Web of Science ®Google Scholar
• HOFER, K. G., and MIVECHI, N. F., 1980, Tumour cell sensitivity to hyperthermia as a function of extracellular and intracellular pH. Journal of National Cancer Institute, 65, 621–625.
   PubMed Web of Science ®Google Scholar
• KONOPLYANNIKOV, A. G., and STEIN, L. V., 1977, Application of hyperthermia for the inhibition of repair processes in malignant cells and for the enhancement of radiotherapy efficiency. Medizinskaya Radiologiya, 2, 23–27.
   Google Scholar
• KUBLIK, L. N., MANTZIGHIN, YU. A., PLOTNIKOVA, E. D., and EIDUS, L. K., 1974, Post-irradiation proection of mammalian cells against ionizing radiation. Radiobiologiya, 14, 83–87.
   PubMedGoogle Scholar
• LEPOCK, J. R., 1982, Involvement of membranes in cellular responses to hyperthermia. Radiation Research, 92,433–438.
   PubMed Web of Science ®Google Scholar
• LITINSKAYA, L. L., KOSTENKO, G. A., VEXLER, A. M., and EIDUS, L. K., 1978, Ehrlich ascites carcinoma: synchronized ultradian rhythms in certain cell parameters. International Journal of Chronobiology, 5, 295–306.
   PubMedGoogle Scholar
• LITINSKAYA, L. L., VEXLER, A. M., IKONNIKOVA, N. I., TUROVESKY, V. B., KOZLOV, D. A., and KHRUST, YU. R., 1984, Microscopic version of the pH determination of individual living cells using fluorescindiacetate. (VINITI) n.5267–84.
   Google Scholar
• MIVECHI, N. F., and DEWEY, W. C, 1984, Effect of glycerol and low pH on heat-induced cell killing and loss of cellular DNA polymerase activities in Chinese hamster ovary cells. Radiation Research, 99, 352–362.
   PubMed Web of Science ®Google Scholar
• MIVECHI, N. F., HOFER, K. G., and HOFER, M. G., 1981, Influence of hypoxia and acidity on thermal radiosensitization and direct heat induced death of BP-8 sarcoma cells. Radiology, 138,465–471.
   PubMedGoogle Scholar
• NASONOV, D. N., and ALEXANDROV, V. J., 1940, Response of Living Matter to Environmental Factors (Moscow: Leningrad).
   Google Scholar
• OVERGAARD, J., 1981, Effect of hyperthermia on the hypoxic fraction in an experimental mammary carcinoma in vivo. British Journal of Radiology, 54, 245–249.
   PubMed Web of Science ®Google Scholar
• VEXLER, A. M., KUBLIK, L. N., DEGTYAREVA, O. V., and EIDUS, L. K., 1983, Dependence of cell radiosensitivity on intracellular pH. Medizinskaya Radiologiya, 7, 16–18.
   Google Scholar
• VEXLER, A. M., KUBLIK, L. N., and EIDUS, L. K., 1985, Regularities of postirradiation modi�fication of cell radiation damage. Com. II. Enhancement of the reproductive cell death by decreased intracellular pH. Medizinskaya Radiologiya (in the press).
   Google Scholar
• WONDERGEM, J., HAVEMAN, J., VAN DER SCHUEREN, E., VAN DER HOEVEN, H., and BREUR, K., 1982, Effect of hyperthermia and misonidazole on the radiosensitivity of a transplantable murine tumour: influence of factors modifying the fraction of hypoxic cells. International Journal of Radiation, Oncology, Biology, Physics, 8,1323–1331.
   PubMedGoogle Scholar
• YERMEKOVA, V. M., KONDAKOVA, N. V., LEVITMAN, M. K., SAUGABAYEVA, K. M., and EIDUS, L. K., 1976, Permeability changes and incorporation of labelled thymidine into DNA and whole cells of the fibroblast culture of Chinese hamsters affected by MEA and reduced temperature. Radiobiologiya, 16, 267–269.
   PubMedGoogle Scholar