6
Views
13
CrossRef citations to date
0
Altmetric
Original Article

A study of the mechanism of hydralazine enhancement of thermal damage in the KHT tumour

, &
Pages 667-679 | Published online: 09 Jul 2009

References

  • Bichel P., Overgaard J. Hyperthermic effect on exponential and plateau ascites tumour cells in virro is dependent on environmental pH. Radiation Research 1977; 70: 449–454
  • Brown J. M. Exploitation of bioreductive agents with vasoactive drugs. Radiation Research, E. M. Fielden, J. F. Fowler, J. H. Hendry, D. Scott. Taylor & Francis, London 1987; Vol. 2: 719–724
  • Brown J. M., Twentyman P. R., Zamvil S. S. Response of RIF-1 tumour in vitro and in C3H/Km mice to X-radiation (cell survival, regrowth delay and tumour control), chemotherapeutic agents and activated macrophages. Journal of the National Cancer Institute 1980; 64: 605–611
  • Chaplin D. J., Acker B. The effect of hydralazine on the tumor cytotoxicity of the hypoxic cell cytotoxin RSU-1069: evidence for therapeutic gain. International Journal of Radiation Oncology, Biology and Physics 1987; 13: 579–585
  • Chaplin D. J. Postirradiation modification of tumour blood flow: a method to increase the effectiveness of chemical radiosensitizers. Radiation Research 1988; 115: 292–302
  • Dewey W. C., Hopwooi L. E., Sapareto S. A., Gerweck L. E. Cellular responses to combinations of hyperthermia and radiation. Radiology 1977; 123: 463–474
  • Dunlop F. R. C., Hand J. W., Dickinson R. J., Field S. B. An assessment of local hypcrthcrmia in clinical practice. Internatioanl Journal of Hyperthermia 1986; 2: 39–50
  • Eddy H. A. Alteration in tumour microvasculature during hyperthermia. Radiology 1980; 137: 515–521
  • Freeman M. L., Dewry W. C., Hopwood L. E. Effect of pH on hyperthermic cell survival. Journal of the National Cancer Instirute. 1977; 58: 1837–1839
  • Gerweck L. E. Modification of cell lethality at elevated temperatures. The pH eflect. Radiation Research 1977; 70: 224–235
  • Gerweck L. E., Nygaard T. G., Burlett M. Response of cells to hyperthermia under acute and chronic hypoxic conditions. Cancer Research 1979; 39: 966–972
  • Gfrweck L. E., Rottinger E. Enhancement of mammalian cell sensitivity to hyperthermia by pH alteration. Radiation Research 1976; 67: 508–511
  • Hahn G. M. Hyperthermia and Cancer. Plenum Press, New York 1982
  • Hill S. A., Denekamp J. The effect of vascular occlusion on the thermal sensitization of a mouse tunlour. British Journal of Radiology 1978; 51: 977–1002
  • Horsman M. R., Christensen K. L., Overgaard J. Hydralazine-induced enhancement of hyperthermic damage in a C3H mammary carcinoma. in vivo. International Journal of Hyperthermia 1989; 5: 123–136
  • Jain R. K., Ward-Hartley K. Tumour blood flow - characterization. modifications and role in hyperthermia. IEEE Transactions: Sonics and Ultrasonics 1984; 31: 504–526
  • Kallman R. F., Silini G., Van Putten L. M. Factors influencing the quantitative estimation of the in vivo survival of cells from solid tumours. Journal of the National Cancer Institute 1967; 39: 359–549
  • Kalmus J., Okunieff P., Vaupel P. Dose-dependent effects of hydralazine on microcirculatory function and hyperthermic response of murine FSall tumours. Cancer Research 1990; 50: 15–19
  • Lagendijk J. J. W., Mooibroek J. Hyperthermia treatment planning. Recent Results in Cancer Research 1986; 101: 119–131
  • Meyer K. R., Hopwood L. E., Gillette E. L. The thermal response of mouse adenocarcinoma cells at low pH. European Journal of Cancer 1979; 15: 1219–1222
  • Moulder J. E., Rockwell S. Hypoxic fractions of solid tumours: experimental techniques. methods of analysis, and a survey of existing data. International Journal of Radiation Oncology. Biology and Physics 1984; 10: 695–717
  • Myers R., Field S. B. Hyperthermia and the oxygen enhancement ratio for damage to baby rat cartilage. British Journal of Radiology 1979; 39: 73–81
  • Nfilsen O. S., Overgard J. Effect of extracellular pH on thermotolerance and recovery of hyperthermic daniage. in vitro. Cancer Research 1979; 39: 2772–2778
  • Overgaard J., Bichel P. The influence of hypoxia and acidity on the hyperthermic response of malignant cells. in vitro. Radiology 1977; 123: 511–514
  • Overgaard J., Neilsen O. S. The role of tissue environmental factors on the kinetics and morphology of tumour cells exposed to hyperthermia. Annals of the New York Academy of Sciences 1980; 335: 254–280
  • Overgaard J. Effect of hyperthermia on malignant cells in vivo. A review and a hypothesis. Cancer 1977; 39: 2637–2646
  • Sapirstein L. A. Regional blood tlow by fractional distribution of indicators. American Journal of Physiology 1958; 193: 161–168
  • Shravistav S., Kaelin W. G., Joines W. T., Jirtle R. Microwave hypertherrnia and its effect on tuniour blood flow in rats. Cancer Research 1983; 43: 4665–4669
  • Song C. W. Effect of local hypertherrnia on blood flow and microenvironment: a review. Cancer Research, Suppl 1984; 44: 4721s–4730s
  • Song C. W., Kang M. S., Rhee J. G., Levitt S. H. Vascular damage and delayed cell death in tumours after hyperthermia. British Journal of Cancer 1980; 41: 309–312
  • Song C. W., Patten M. S., Cheistrom L. M., Rhee I. G., Leviit S. H. Effect of multiple heatings on the blood flow in RIF-1 turnours. skin and muscle of C3H mice. International Journal of Hyporthermia 1987; 3: 535–545
  • Stratford I. J., Adams G. E., Godden J., Howells N. Induction of tumour hypoxia post-irradiation: a method for increasing the sensitizing efficiency of misonidazole and RSU 1069 in. vivo. International Journal of Radiation Biology 1989; 55: 411–422
  • Stratford I. J., Adams G. E., Godden J., Nolan J., Howells N., Timpson N. Potentiation of the anti-tumour effect of melphalan by the vasoactive agent, hydralazine. British Journal of Cancer 1988; 58: 122–127
  • Twentyman P. R., Brown J. M., Gray J. W., Franko A. J., Scoles M. A., Kallman R. F. A new mwse model tumour system (RIF-1) for comparison of endpoint studies. Journal of the National Cancer Institute 1980; 64: 595–604
  • Voorhees W. D., Babbs C. F. Hydralazine-enhanced selective heating of transmissible venereal tuniour implants in dogs. European Journal of Cancer and Clinical Oncology 1982; 18: 1027–1033
  • Wallen C. A., Colby T. V., Stewart J. R. Cell kill and tumour control after heat treatment with and without vascular occlusion in RIF-1 tumours. Radiation Resectrch. 1986; 106: 215–223
  • Walton M. I. The effects of hyperthermia on the pharmacokinetics of selected anticancer drugs. PhD Thesis. figure 3.5. University of Cambridge, UK 1988
  • Walton M. I., Cattermole D., Bleehen N. M. A microcomputer-controlled, local hyperthermia system for uniform tuniour heating in unanaesthetized mice. International Journal of Hyperthermia 1989; 5: 53–58

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.