Role of cellular membranes in hyperthermia: Some observations and theories reviewed

References

• Aloia R. C. The role of membrane fatty acids in mammalian hibernation. Federation Proceedings 1980; 39: 2974–2979
   PubMedGoogle Scholar
• Anderson R. L., Parker R. Analysis of membrane lipid composition of mammalian cells during the development of thermo tolerance. International Journal of Radiation Biology 1982; 42: 57–69
   Web of Science ®Google Scholar
• Anderson R. L., Tag T., Hahn G. M. Membrane lipids of B16 melanoma cells and heat resistant variants. International Journal of Radiation Biology 1988; 54: 813–823
   PubMed Web of Science ®Google Scholar
• Anderstam B., Vaca C., Harms-Ringdahl M. Lipid peroxide levels in a murine adenocarcinoma exposed to hyperthermia: the role of glutathione depletion. Radiation Research 1992, In press
   PubMedGoogle Scholar
• Aszalos A., Yang G. C., Gottesman M. M. Depolymerization of microtubles increases the motional freedom of molecular probes in cellular plasma membranes. Journal of Cell Biology 1985; 100: 1357–1362
   PubMed Web of Science ®Google Scholar
• Bagi C., Hidvegi E. J. Protein phosphorylation and kinase activities in tumour cells after hyperthermia. International Journal of Radiation Biology 1990; 58: 633–650
   PubMed Web of Science ®Google Scholar
• Barker C. J., Bowler K. Lipid composition of the membranes from cells of two rat tumors and its relationship to tumor thermosensitivity. Radiation Research 1991; 125: 48–55
   PubMed Web of Science ®Google Scholar
• Barklis E., Yatvin M. The life cycle of retroviruses: the influence of hyperthermia and membrane organization. Advances in Membrane Fluidity. 6: Membrane Interactions of Human Immunodeficiency Virus: Implications for Pathogenesis and Therapy in AIDS, R. C. Aloia, C. C. Curtain. Alan R. Liss, New York 1992; 215–236
   Google Scholar
• Barratt G. H., Wills E. D. The effect of hyperthermia and radiation on lysosomal enzyme activity of mouse mammary tumors. European Journal of Cancer 1979; 15: 243–250
   Google Scholar
• Bates D. A., MacKillop W. J. Effect of hyperthermia on the sodium-potassium pump in CHO cells. Radiation Research 1985; 103: 441–451
   PubMedGoogle Scholar
• Borochov H., Shinitzky M., Abbott R. E. Modulation of erythrocyte membrane proteins by membrane cholesterol and lipid fluidity. Biochemistry 1979; 18: 251–255
   PubMedGoogle Scholar
• Bowler K. Cellular heat injury—are membranes involved. S. E. B. Symposium XLI: Temperature and Animal Cells, K. Bowler, B. J. Fuller. Company of Biologists, Cambridge 1987; 157–185
   Google Scholar
• Bowler K., Duncan D. J., Gladwell R. T., Davidson T. F. Cellular heat injury. Comparative Biochemistry and Physiology 1973; 45: 441–449
   Google Scholar
• Cheng K. H., Hui S. W., Lepock J. R. Protection of the membrane Ca-ATPase by cholesterol from thermal activation. Cancer Research 1987; 47: 1255–1262
   PubMed Web of Science ®Google Scholar
• Cherry R. Modulation of protein-protein interaction in membranes. Biochemical Society Transactions 1987; 15: 91–93
   PubMedGoogle Scholar
• Chu G. L., Dewey W. C. Effect of hyperthermia on intracellular pH in Chinese hamster ovary cells. Radiation Research 1987; 110: 439–449
   PubMed Web of Science ®Google Scholar
• Clark A. W., Robins H. S., Vorpahl J. W., Yatvin M. B. Structural changes in murine cancer associated with hyperthermia and lidocaine. Cancer Research 1983; 43: 1716–1723
   PubMed Web of Science ®Google Scholar
• Coakley W. T. Hyperthermia effects on the cytoskeleton and on cell morphology. S. E. B. Symposium XLI: Temperature and Animal Cells, K. Bowler, B. J. Fuller. Company of Biologists, Cambridge 1987; 187–212
   Google Scholar
• Cook J., Fox M. H. The kinetics of intracellular pH changes induced by hyperthermia. Abstract, 34th annual meeting of the Radiation Research Society. 1984
   Google Scholar
• Coss R. A., Dewey W. C. Mechanism of heat sensitization of G1-and S-phase cells by procaine HC1. Tumor Biology and Therapy, J. J. Broese, G. W. Barendson, H. B. Kal, A. J. Vander Kogel. Martinus Nijhoff, Amsterdam 1983; D6–05
   Google Scholar
• Coss R. A., Dewey W. C. Heat sensitization of Gl and S phase cells by procaine HC1. II: toxicity and probability of dividing following treatment. International Journal of Hyperthermia 1988; 4: 687–697
   PubMed Web of Science ®Google Scholar
• Coss R. A., Dewey W. C., Bamberg J. R. Effects of hyperthermia (41±5°C) on Chinese hamster ovary cells analysed in mitosis. Cancer Research 1979; 39: 1911–1918
   PubMed Web of Science ®Google Scholar
• Coss R. A., Dewey W. C., Bamberg J. R. Effects of hyperthermia on microtubles in vitro and on dividing Chinese hamster ovary cells. National Cancer Institute Monograph 1982a; 61: 53–55
   Google Scholar
• Coss R. A., Dewey W. C., Bamberg J. R. Effects of hyperthermia on dividing Chinese hamster ovary cells and on microtubles. in vitro. Cancer Research 1982b; 42: 1059–1971
   PubMed Web of Science ®Google Scholar
• Cress A. E., Gerner E. W. Cholesterol levels inversely reflect the thermal sensitivity of mammalian cells in culture. Nature 1980; 283: 677–679
   PubMed Web of Science ®Google Scholar
• Dennis W. H., Yatvin M. B. Correlation of hyperthermic sensitivity and membrane microviscosity in E. coli K1060. International Journal of Radiation Biology 1981; 39: 265–271
   Web of Science ®Google Scholar
• Dewey W. C. Mechanisms of thermal injury and thermal sensitization. Proceedings of the 5th International Symposium on Hyperthermic Oncology, KyotoJapan, August 29-September 3, 1988, T. Sugahara, M. Saito. Taylor & Francis, London, 75–80, Hyperthermic Oncology
   Google Scholar
• Dewey W. C., Westra A., Miller H. H., Nagasawa H. Heat induced lethality and chromosomal damage in CHO cells treated with 5 Bu-dR. International Journal of Radiation Biology 1971; 20: 505–520
   Web of Science ®Google Scholar
• Dickson J. A., Calderwood S. K. Thermosensitivity of neoplastic tissues in vivo. Hyperthermia and Cancer Therapy, F. K. Storm. G. K. Hall, Boston 1983; 63–140
   Google Scholar
• Drummond I. A. S., Livingstone D., Steinhardt R. A. Heat shock protein synthesis and cytoskeleton rearrangements occur independently of intracellular free Ca2- increases. Radiation Research 1988; 113: 402–413
   PubMed Web of Science ®Google Scholar
• Dynlacht J. R., Fox M. H. Heated-induced changes in the membrane fluidity of Chinese hamster ovary cells measured by flow cytometry. Radiation Research 1992a; 130: 48–54
   PubMedGoogle Scholar
• Dynlacht J. R., Fox M. H. The effect of 45°C hyperthermia on the membrane fluidity of cells of several lines. Radiation Research 1992b; 130: 55–60
   PubMed Web of Science ®Google Scholar
• Dynlacht J. R., Fox M. H. Effects of hyperthermia and membrane-active compounds or low pH on the membrane fluidity of Chinese hamster ovary cells. International Journal of Hyperthermia 1992c; 8: 351–362
   PubMed Web of Science ®Google Scholar
• Elegbede A. J., Elson C. E., Qureshi A., Dennis W. H., Yatvin M. B. Increasing the thermosensitivity of a mammary tumor (CA755) through dietary modification. European Journal of Cancer and Clinical Oncology 1986; 22: 607–615
   PubMedGoogle Scholar
• Fisher B., Kraft P., Hahn G. M., Anderson R. L. Thermotolerance in the absence of induced heat shock proteins in a murine lymphoma. Cancer Research 1992; 52: 2854–2861
   PubMed Web of Science ®Google Scholar
• Flanagan J., Koch G. L. E. Cross-linked surface Ig attached to actin. Nature 1978; 273: 278–281
   PubMed Web of Science ®Google Scholar
• Gerner E. W., Cress A. E., Stickney D. G., Holmes D. K., Culver P. S. Factors regulating membrane permeability alter thermal resistance. Annals of the New York Academy of Sciences 1980; 335: 215–233
   PubMedGoogle Scholar
• Glass J. R., De Witt R. G., Cress A. E. Rapid loss of stress fibres in CHO cells after hyperthermia. Cancer Research 1985; 45: 258–262
   PubMed Web of Science ®Google Scholar
• Gonzalez-Mendez R., Minton K. W., Hahn G. M. Lack of correlation between membrane lipid composition and thermotolerance in Chinese hamster ovary cells. Biochimica et Biophysica Acta 1982; 692: 168–170
   PubMed Web of Science ®Google Scholar
• Guffy M. M., Rosenberger J. A., Simon I., Burns C. P. Effect of cellular fatty acid alteration on hyperthermic sensitivity in cultured L1210 murine leukemia cells. Cancer Research 1982; 42: 3625–3630
   PubMed Web of Science ®Google Scholar
• Hahn G. M., Li G. C., Shiu E. C. Interaction of amphotericin B and 43°C hyperthermia. Cancer Research 1977; 37: 761–764
   PubMed Web of Science ®Google Scholar
• Harmon B. V., Corder A. M., Collins R. J., Gobe G. C., Allen J., Allan D. J., Kerr J. F. R. Cell death induced in murine mastocytoma by 42–47°C heating in vitro: evidence that the form of death changes from apoptosis to necrosis above a critical heat load. International Journal of Radiation Biology 1990; 58: 845–858
   PubMed Web of Science ®Google Scholar
• Harms-Ringdahl M., Anderstam B., Vaca C. Heat induced changes in the incorporation of 3H-acetate in membrane lipids. International Journal of Radiation Research 1987; 52: 315–324
   Google Scholar
• Harms-Ringdahl M., Anderstam B., Vaca C. Incorporation of 3H-acetate in to the membrane lipids of a murine tumor during the development of thermotolerance. International Journal of Radiation Research 1989; 55: 297–305
   PubMed Web of Science ®Google Scholar
• Hauser H., Penkett S. A., Chapman D. Nuclear magnetic resonance spectroscopy studies of procaine hydrochloride and tetracaine hydrochloride at lipid-water interfaces. Biochimica et Biophysica Acta 1969; 183: 466–472
   PubMedGoogle Scholar
• Hazel J. R. The effect of temperature acclimation upon succinic dehydrogenase activity from the epaxial muscle of the common goldfish. Comparative Biochemistry and Physiology 1972; 43: 863–882
   Google Scholar
• Henle K. J., Leeper D. B. Effects of hyperthermia (45°C) on macromolecular synthesis in CHO cells. Cancer Research 1979; 39: 2665–2674
   PubMed Web of Science ®Google Scholar
• Hidvegi E. J., Yatvin M. B., Dennis W. H., Hidvegi E. Effect of altered membrane lipid composition and procaine on hyperthermia killing of ascites cells. Oncology 1980; 37: 360–363
   PubMed Web of Science ®Google Scholar
• Hofer K. G., Mivechi N. F., Hofer M. G. Effect of membrane and cytoskeleton modification of the heat response of BP-8 murine sarcoma cells. Protoplasma 1989; 150: 117–123
   Google Scholar
• Jain M. K., White H. B. Long range order in biomembranes. Advances in Lipid Research 1977; 15: 1–60
   PubMedGoogle Scholar
• Jorritsma J. B. M., Konings A. W. T. The occurrence of DNA strand breaks after hyperthermic treatment of mammalian cells with and without radiation. Radiation Research 1984; 98: 198–208
   PubMed Web of Science ®Google Scholar
• Jung H. Models and mechanisms of hyperthermia. Hyperthermic Oncology, T. Sugahara, M. Saito. Taylor & Francis, London 1988; 103–106
   Google Scholar
• Jung H., Okumara Y. Mechanisms of thermal killing of cells. Hyperthermic Oncology, T. Sugahara, M. Saito. Taylor & Francis, London 1988; 101–102
   Google Scholar
• Keech M. L., Wills E. D. The effect of hyperthermia on activation of lysosomal enzymes in HeLa cells. European Journal of Cancer 1979; 15: 1025–1031
   Google Scholar
• Koch G. L. E., Smith M. J. An association between actin and the major histocompatibility antigen H-2. Nature 1978; 273: 274–278
   PubMed Web of Science ®Google Scholar
• Konings A. W. T. Effects of heat and radiation on mammalian cells. Radiation Physics and Chemistry 1987; 30: 339–349
   Web of Science ®Google Scholar
• Konings A. W. T. Membranes as targets for hyperthermic cell killing. Recent Results in Cancer Research 1988; 109: 9–21
   PubMedGoogle Scholar
• Konings A. W. T., Ruifrok A. C. C. Role of membrane lipids and membrane fluidity in thermosensitivity and thermotolerance in mammalian cells. Radiation Research 1985; 102: 86–98
   PubMed Web of Science ®Google Scholar
• Korvovsky M. J., Kleinfield A. M., Hoover R. L., Klasner R. O. The concept of lipid domains in membranes. Journal of Cellular Biology 1982; 94: 1–6
   PubMedGoogle Scholar
• Koter M. Effect of hyperthermia on the internal microviscosity of erythrocytes and lymphocytes—a spin label study. International Journal of Radiation Biology 1991; 58: 157–164
   Google Scholar
• Kozak S. L., Kabat D. Ping-Pong amplification of a retroviral vector achieves high-level gene expression: human growth hormone production. Journal of Virology 1990; 64: 3500–3508
   PubMed Web of Science ®Google Scholar
• Kwock K., Lin P., Hefter K., Wallach D. F. H. Impairment of rate dependent amino-acid transport in a cultured human T-cell line by hyperthermia and irradiation. Cancer Research 1978; 38: 83–87
   PubMed Web of Science ®Google Scholar
• Lepock J. R. Involvement of membranes in cellular responses to hyperthermia. Radiation Research 1982; 92: 433–438
   PubMed Web of Science ®Google Scholar
• Lepock J. R., Massocpte-Nolan P., Role G. S., Kruuv J. Lack of correlation between hyperthermic cell killing, thermotolerance and membrane fluidity. Radiation Research 1981; 87: 330–331
   Google Scholar
• Lepock J. R., Cheng K.-H., Al-Qysi H., Kruuv J. Thermotropic lipid and protein transitions in Chinese hamster lung cell membrane: relationship to hyperthermic cell killing. Canadian Journal of Biochemical Cell Biology 1983; 61: 421–427
   PubMedGoogle Scholar
• Lepock J. R., Frey H. E., Rodahl A. M., Kruuv J. Thermal analysis of CHL-V79 cells using differential scanning calorimetry: implications for hyperthermic cell killing and heat shock response. Journal of Cell Physiology 1988; 137: 14–24
   PubMed Web of Science ®Google Scholar
• Leyko W., Bartosz G. Membrane effects of ionizing radiation and hyperthermia. International Journal of Radiation Biology 1986; 49: 743–770
   Web of Science ®Google Scholar
• Li G. C., Hahn G. M. Ethanol-induced tolerance to heat and adriamycin. Nature (London) 1978; 274: 694–701
   Google Scholar
• Lin P. S., Turi A., Kwock L., Lu R. C. Hyperthermic effect on microtubule organization. National Cancer Institute Monograph 1982; 61: 57–60
   Google Scholar
• Lipsky N. G., Pagano R. E. Sphingolipid metabolism in cultured fibroblasts: microscopic and biochemical studies employing a fluorescent ceramide analogue. Proceedings of the National Academy of Sciences (USA) 1983; 80: 2608–2612
   PubMed Web of Science ®Google Scholar
• Lunec J., Hesslewood I. P., Parker R., Leeper S. Hyperthermia enhancement of radiation killing in HeLa cells. Radiation Research 1981; 85: 116–125
   PubMed Web of Science ®Google Scholar
• Marinett G. Arrangement of phosphotidylserine and phosphotidyl-ethanolamines in erythrocyte membranes. Biochimica et Biophysica Acta 1972; 465: 198–209
   Google Scholar
• Massicote-Nolan P., Glocheski D. J., Kruuv J., Lepock J. R. Relationship between hyperthermic cell killing and protein denaturation by alcohol. Radiation Research 1981; 87: 284–299
   PubMedGoogle Scholar
• McClain D. E., Trypus C. A. Effect of gamma radiation on membrane fluidity of Molt-4 nuclei. Radiation Research 1990; 123: 263–267
   PubMed Web of Science ®Google Scholar
• Mehdi S., Rectenwald D. J., Smith L. M., Li G. C., Armour E. P., Hahn G. M. Effect of hyperthermia on murine cell surface incompatibility antigens. Cancer Research 1984; 44: 3394–3397
   PubMed Web of Science ®Google Scholar
• Mondovi B., Agro A. P., Rotilio G., Strom R., Moricca G., Fanelli A. R. The biochemical mechanism of selective heat sensitivity of cancer cells, II: Studies on nucleic acids and protein synthesis. European Journal of Cancer 1969; 5: 137–146
   PubMedGoogle Scholar
• Mulcahy R. T., Gould M. N., Hidvegi E. J., Elson C. E., Yatvin M. B. Hyperthermia and surface morphology of P388 ascites tumor cells. Radiation Research 1981; 39: 95–106
   Google Scholar
• Nicolson G. L., Smith J. R., Poste G. Effects of local anaesthetics on cell morphology and membrane associated cytoskeletal organization in BALB/3T3 cells. Journal of Cell Biology 1976; 68: 395–402
   PubMed Web of Science ®Google Scholar
• Pagano R. E., Sleight R. G. Defining lipid transport pathways in animal cells. Science 1985; 229: 1051–1057
   PubMedGoogle Scholar
• Papahadjopoulos D. Studies on the mechanism of action of local anaesthetics with phospholipid model membranes. Biochimica et Biophysica Acta 1972; 265: 169–186
   PubMed Web of Science ®Google Scholar
• Parassi T., Sapora O., Girsti A. M., De Stasio G., Ravagnan G. Alterations in erythrocyte membrane lipids induced by low doses of ionizing radiation as revealed by DPH fluorescence lifetime. International Journal of Radiation Biology 1992; 59: 59–69
   Google Scholar
• Perlaky L., Lee Y., Dewey W. C. Heat-induced morphological alterations in non-tolerant and thermotolerant cells. International Journal of Radiation Biology 1991; 60: 819–832
   PubMed Web of Science ®Google Scholar
• Reiter T., Penman S. ‘Prompt’ heat shock proteins. Translationally regulated synthesis of new proteins associated with the nuclear matrix-intermediate filaments as an early response to heat shock. Proceedings of the National Academy of Sciences (USA) 1983; 80: 4737–4741
   PubMed Web of Science ®Google Scholar
• Roos A., Boron W. Intracellular pH. Physiological Reviews 1981; 61: 296–434
   PubMed Web of Science ®Google Scholar
• Rothman J. E., Lenard L. Membrane asymmetry. Science 1977; 195: 743–753
   PubMed Web of Science ®Google Scholar
• Roti-Roti J. L., Laszlo A. The effects of hyperthermia on cellular macromolecules. Hyperthermia and Oncology 1988; 1: 13–56
   Google Scholar
• Ruifrok A. C. C. Hyperthermic cell killing: role of the plasma membrane. University of Gronigen, GronigenThe Netherlands 1986, Thesis
   Google Scholar
• Ruifrok A. C. C., Kanon B., Konings A. W. T. Na+/K+ ATPase activity in mouse lung fibroblasts and HeLa S3 cells during and after hyperthermia. International Journal of Hyperthermia 1986; 2: 51–59
   PubMedGoogle Scholar
• Saad A. H., Hahn G. M. Activation of potassium channels: relationship to heat shock response. Proceedings of the National Academy of Science, USA 1992; 89: 9396–9399
   PubMedGoogle Scholar
• Schamart D. H. J., Van Walraven H. S., Wiegant F. A., Linnemans W. A. M., Van Run J., Van den Berg J., Van Wijk R. Thermotolerance in hepatoma cells. Radiation Research 1984; 98: 82–95
   PubMedGoogle Scholar
• Sefton B. M., Buss J. E. The covalent modification of eukaryotic proteins with lipid. Journal of Cell Biology 1987; 104: 1449–1453
   PubMed Web of Science ®Google Scholar
• Shinitzky M., Skornick Y., Haran-Ghera N. Effective tumor immunization induced by cells of elevated membrane-lipid microviscosity. Proceedings of the National Academy of Sciences (USA) 1979; 76: 5313–5316
   PubMedGoogle Scholar
• Siegant F. A. C., Tuly M., Linnemans W. A. M. Calmodulin inhibitors potentiate hyperthermic killing. International Journal of Hyperthermia 1985; 1: 157–169
   PubMedGoogle Scholar
• Skibba J. L., Powers R. H., Standicka A., Cullinane D. W., Almagro U. A., Kalbfleisch J. H. Oxidative stress as a precursor to irreversible hepatocellular injury caused by hyperthermia. International Journal of Hyperthermia 1991; 7: 749–761
   PubMed Web of Science ®Google Scholar
• Stevenson M. A., Calderwood S. K., Hahn G. M. Effect of hyperthermia on Ca flux in CHO fibroblasts. Cancer Research 1987; 47: 3712–3717
   PubMed Web of Science ®Google Scholar
• Van Bergen En Henegomen P. M. P., Jordi W. J. R. M., Van Dongen G., Ramaekers F. C. S., Amesz H., Linnemans W. A. Studies on a possible relationship between alterations in the cytoskeleton and induction of heat shock protein synthesis in mammalian cells. International Journal of Hyperthermia 1985; 1: 69–83
   PubMedGoogle Scholar
• Van Dijk P. W. M., De Kruijff B., Van Deenen L. L. M., De Gier J., Demel R. A. The preference of cholesterol for phosphotidylcholine in mixed bilayers. Biochimica et Biophysica Acta 1976; 455: 576–587
   PubMedGoogle Scholar
• Verma S. P., Rastoge A. Role of proteins in protection against radiation induced damage in membranes. Radiation Research 1990; 122: 130–136
   PubMed Web of Science ®Google Scholar
• Vidair C., Dewey W. C. Evaluation of a role for intracellular Na+, K+, Ca2+ and Mg2+ in hyperthermic killing. Radiation Research 1986; 105: 187–200
   PubMed Web of Science ®Google Scholar
• Vilenchik M. M. Studies in DNA damage and repair of thermal and radiation-induced lesions in human cells. International Journal of Radiation Biology 1989; 52: 505–517
   Google Scholar
• Wainberg R. H., Walden T. L., Stebler B. A., Yatvin M. B. Effect of diet on hyperthermia-induced lethality and prostaglandin release. Prostaglandins 1991; 41: 501–503
   PubMedGoogle Scholar
• Wainberg R. H., Grummer M. A., Elson C. E., Cramp W. A., Yatvin M. B. Membrane and cell composition changes of P388 and 3T3 cells following heating. International Journal of Hyperthermia 1992, submitted
   Google Scholar
• Warters R. L., Brizgys L. M. Apruinic site induction in the DNA of cells heated at hyperthermic temperatures. Journal of Cell Physiology 1987; 133: 144–150
   PubMed Web of Science ®Google Scholar
• Warters R. L., Axtell J-O. Repair of DNA strand breaks at hyperthermic temperatures in CHO cells. International Journal of Radiation Biology 1992; 61: 43–48
   PubMed Web of Science ®Google Scholar
• Warters R. L., Henle K. J. DNA degradation in CHO cells after exposure to hyperthermia. Cancer Research 1982; 42: 4427–4432
   PubMed Web of Science ®Google Scholar
• Warters R. L., Roti-Roti J. Hyperthermia and the cell nucleus. Radiation Research 1982; 92: 458–462
   PubMed Web of Science ®Google Scholar
• Welch W. J., Suhan J. P. Morphological study of the mammalian stress response. Journal of Cell Biology 1985; 101: 1198–1211
   PubMed Web of Science ®Google Scholar
• Wong G., Dewey W. C. Molecular studies in the hyperthermic inhibition of DNA synthesis in CHO cells. Radiation Research 1982; 92: 370–395
   PubMed Web of Science ®Google Scholar
• Wunderlich F., Kreutz W., Mahler P., Konai A., Heppler G. Thermotropic fluid-ordered ‘discontinuous’ phase separation in microsomal lipids of Tetrahymena: an X-ray diffraction study. Biochemistry 1978; 17: 2005–2010
   PubMedGoogle Scholar
• Yatvin M. B. The influence of membrane lipid composition and procaine on hyperthermic death of cells. International Journal of Radiation Biology 1977; 32: 513–521
   Web of Science ®Google Scholar
• Yatvin M. B. Influence of membrane-lipid composition on translocation of nascent proteins in heated. Escherichia coli. Biochimica et Biophysica Acta 1987; 901: 147–156
   PubMedGoogle Scholar
• Yatvin M. B., Dennis W. H. Membrane lipid composition and sensitivity to cell killing by hyperthermia, procaine and radiation. Cancer Therapy by Hyperthermia and Radiation, C. S. Streffer. Urban & Schwarzenberg, Munich 1978; 157–159
   Google Scholar
• Yatvin M. B., Grummer M. A. Membrane structure and radiation and hyperthermic damage. Radiation and Physical Chemistry 1987; 30: 351–364
   Web of Science ®Google Scholar
• Yatvin M. B., Vorpahl J. W., Gould M. N., Lyte M. The effects of membrane modification and hyperthermia on the survival of p388 and V79 cells. European Journal of Cancer and Clinical Oncology 1983; 19: 1247–1253
   PubMedGoogle Scholar
• Yatvin M. B., Gipp J. J., Klessig D. R., Dennis W. H. Hyperthermic sensitivity and growth stage in. Escherichia coli. Radiation Research 1986a; 106: 78–88
   PubMed Web of Science ®Google Scholar
• Yatvin M. B., Seigel F. L., Smith K. M. Translocation of nascent non-signal sequence protein in heated. Escherichia coli. Journal of Biochemistry 1986b; 261: 8070–8075
   PubMed Web of Science ®Google Scholar
• Yatvin M. B., Dennis W. H., Elegbede J. A., Elson C. E. Sensitivity of tumor cells to heat and ways of modifying the response. Temperature and Animal Cells, K. Bowler, B. J. Fuller. Company of Biologists, Cambridge 1987; 235–267
   Google Scholar
• Yau T. M. Procaine mediated modification of membranes and of the response to X-irradiation and hyperthermia in mammalian cells. Radiation Research 1979; 80: 523–541
   PubMed Web of Science ®Google Scholar
• Yi P. N., Fenn J. O., Jarrett J. H. Hyperthermia and osmoregulation. Abstract, 35th Annual Meeting of the Radiation Research Society. 1985
   Google Scholar