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Original Article

Manipulation of intra- and extracellular pH in spontaneous canine tumours by use of hyperglycaemia

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Pages 745-754 | Received 14 Aug 1992, Accepted 27 Jan 1993, Published online: 09 Jul 2009

References

  • Acker J. C., Dewhirst M. W., Honore G. M., Samulski T. V., Tucker J. A., Oleson J. R. Blood perfusion measurements in human tumours: evaluation of laser Doppler methods. International Journal of Hyperthermia 1990; 6: 287–304
  • Ashby B. S. pH studies in human malignant tumors. Lancet 1966; ii: 312–315
  • Brown T. R., Kincaid B. M., Ugurbil K. NMR chemical shift imaging in three dimensions. Proceedings of the National Academy of Sciences, USA 1982; 79: 3523–3526
  • Calderwood S. K., Dickson J. A. pH and tumor response to hyperthermia. Advances in Radiation Biology 1983; 10: 135–190
  • Cook J. A., Fox M. H. Effects of chronic pH 6.6 on growth, intracellular pH, and response to 42.0°C hyperthermia of Chinese Hamster Ovary cells. Cancer Research 1988; 48: 2417–2420
  • Dipette D. J., Ward-Hartley K. A., Jain R. K. Effect of glucose on systemic hemodynamics and blood flow rate in normal and tumor tissues in rats. Cancer Research 1986; 46: 6299–6304
  • Gerweck L. E. Modification of cell lethality at elevated temperatures: the pH effect. Radiation Research 1977; 70: 224–235
  • Gerweck L. E., Rottinger E. Enhancement of mammalian cell sensitivity to hyperthermia by pH alteration. Radiation Research 1976; 67: 508–511
  • Hofer K. G., Mivechi N. F. Tumor cell sensitivity to hyperthermia as a function of extracellular and intracellular pH. Journal of the National Cancer Institute 1980; 65: 621–625
  • Hollis D. P. Nuclear magnetic resonance studies of cancer and heart disease. Bulletin of Magnetic Resonance 1979; 1: 27–37
  • Krag D. N., Storm F. K., Morton D. L. Induction of transient hyperglycaemia in cancer patients. International Journal of Hyperthermia 1990; 6: 741–744
  • Thistlethwaite A. J., Alexander G. A., Moylan D. J., Leeper D. B. Modification of human tumor pH by elevation of blood glucose. International Journal of Radiation Oncology, Biology and Physics 1987; 13: 603–610
  • Vaupel P. W., Okunieff P. G. Role of hypovolemic hemoconcentration in dose-dependent flow decline observed in murine tumors after intraperitoneal administration of glucose or mannitol. Cancer Research 1988; 48: 7102–7106
  • Ward K. A., Dipette D. J., Held T. N., Jain R. K. Effect of i.v. versus i.p. glucose injection on systemic hemodynamics and blood flow rate in normal and tumor tissue in rats. Cancer Research 1991; 51: 3612–3616
  • Ward K. A., Jain R. K. Response of tumours to hyperglycaemia: characterization, significance and role in hyperthermia. International Journal of Hyperthermia 1988; 4: 223–250
  • Ward K. A., Jain R. K. Blood flow response to hyperglycemia. Tumor Blood Supply and Metabolic Microenvironment, P. Vaupel, R. K. Jain. Fischer Verlag, Stuttgart 1991

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