Advanced search
Publication Cover
International Journal of Hyperthermia Volume 13, 1997 - Issue 1
Submit an article Journal homepage
81
Views
3
CrossRef citations to date
0
Altmetric
Original Article

Effect of lactic acid in tumours on antitumour activity of hyperthermia

K. Hirokawa Department of Radiology, and Radioisotope Center, Osaka City University Medical School, Osaka, 545, Japan
,
K. Kageyama Department of Radiology, and Radioisotope Center, Osaka City University Medical School, Osaka, 545, Japan
,
T. Nakajima Department of Radiology, and Radioisotope Center, Osaka City University Medical School, Osaka, 545, Japan
,
M. Tsumura Department of Radiology, and Radioisotope Center, Osaka City University Medical School, Osaka, 545, Japan
&
Y. Onoyama Department of Radiology, and Radioisotope Center, Osaka City University Medical School, Osaka, 545, Japan
Pages 115-123 | Received 07 Sep 1995, Accepted 19 Aug 1996, Published online: 09 Jul 2009

References

  • Alcock N. W. A simple procedure for the extraction and esterification of some organic acids. Analytical Biochemistry 1965; 11: 335–341
  • Burdon R. H., Kerr S. M., Cutmore C. M. M., Munro J., Gill V. Hyperthermia, Na + K + ATPase and lactic acid production in some human tumor cells. British Journal of Cancer 1984; 49: 437–445
  • Calderwood S. K., Dickson J. A. Effect of hyperglycemia on blood flow, pH, and response to hyperthermia (42°C) of the Yoshida sarcoma in the rat. Cancer Research 1980; 40: 4728–4733
  • Cook J. A., Fox M. H. Effects of chronic pH 6.6 on growth, intracellular pH, and response to 42.0°C hyperthermia of Chinese hamster ovary cells. Cancer Research 1988; 48: 2417–2420
  • Chu G. L., Dewey W. C. The role of low intracellular or extracellular pH in sensitization to hyperthermia. Radiation Research 1988; 114: 154–167
  • DiPette D. J., Ward-Hartley K. A., Jain R. K. Effect of glucose on systemic hemodynamics and blood flow rate in normal and tumor tissues in rats. Cancer Research 1986; 46: 6299–6304
  • Freeman M. L., Dewey W. C., Hopwood L. E. Effect of pH on hyperthermic cell survival: brief commentation. Journal of the National Cancer Institute 1977; 58: 1837–1839
  • Gerweck L. E. Modification of cell lethality at elevated temperatures. The pH Effect. Radiation Research 1977; 70: 224–235
  • Gullino P. M., Grantham F. H., Smith S. H., Haggerty A. C. Modifications of the acid-base status of the internal milieu of tumors. Journal of the National Cancer Institute 1965; 34: 857–869
  • Jain R. K., Shah S. A., Finney P. L. Continuous noninvasive monitoring of pH and temperature in rat Walker 256 carcinoma during normoglycemia and hyperglycemia. JNGI 1984; 73: 429–436
  • Kageyama K., Onoyama Y., Nakajima T., Tumura M., Nishita T., Kogawa H., Tanabe K. Rapid and simple gas chromatographic measurement of lactic acid in red blood cell, plasma and tumor cells after hyperthermia. Life Sciences 1992; 51: 407–410
  • Koutcher J. A., Fellenz M. P., Vaupel P. W., Gerweck L. E. FSall mouse tumor metabolic changes with different doses of glucose measured by 31P nuclear magnetic resonance. Cancer Research 1988; 48: 5917–5921
  • Kruger W., Mayer W. K., Schaefer C., Stohrer M., Vaupel P. Acute changes of systemic parameters in tumor-bearing rats, and of tumor glucose, lactate, and ATP levels upon local hyperthermia and/or hyperglycaemia. Journal of Cancer Research and Clinical Oncology 1991; 117: 409–415
  • Meyer K. A., Kammerling E. M., Amtman L., Koller M., Hoffman S. J. pH study of malignant tissues in human beings. Cancer Research 1948; 8: 513–518
  • Rhee J. G., Eddy H. A., Salazar O. M., Lyons J. C., Song C. W. A differential low pH effect on tumor cells grown in vivo and in vitro when treated with hyperthermia. International Journal of Hypertherrnia 1991; 7: 75–84
  • Ryu K. H., Song C. W. Changes in lactic acid content in tumors by hyperthermia. Radiation Research 1982; 91: 319–320
  • Schaefer C., Mayer W. K., Kruger W., Vaupel P. Microregional distributions of glucose, lactate, ATP and tissue pH in experimental tumors upon local hyperthermia and/or hyperglycaemia. Journal of Cancer Research and Clinical Oncology 1993; 119: 599–608
  • Urano M., Montoya V., Booth A. Effect of hyperthermia on the thermal response of murine normal and tumor tissues. Cancer Research 1983; 43: 453–455
  • Vaupel P. W., Frinak S., Bicher H. I. Heterogeneous oxygen partial pressure and pH distribution in C3H mouse mammary adenocarinoma. Cancer Research 1981; 41: 2008–2013
  • Warburg O. On the origin of cancer cells. Science 1956; 24: 309–314
  • Ward-Hartley K. A., Jain R. K. Effect of glucose and galactose on micro-circulatory flow in normal and neoplastic tissues in rabbits. Cancer Research 1987; 47: 371–377
  • Ward K. A., DiPette D. J., Held T. N., Jain R. K. Effect of intravenous versus intraperitoneal glucose injection on systemic hernodynamics and blood flow rate in normal and tumor tissues in rats. Cancer Research 1991; 51: 3612–3616
  • Ward K. A., Jain R. K. Response of tumors to hyperglycaemia: characterization, significance and role in hyperthermia. International Journal of Hyperthermia 1988; 4: 223–250

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.