IL-6 polymorphism associated with fatal outcome in patients with severe traumatic brain injury

References

• Kraus JF, MacArthur DL, Silverman TA, Jayaraman N. Epidemiology of brain injury. Neurotrauma, RK Narayan, JE Wilberger, Jr, JT Povlishock. McGraw-Hill, New York 1996; 13–30
   Google Scholar
• Schmidt OI, Heyde CE, Ertel W, Stahel PF. Closed head injury - an inflammatory disease?. Brain Research Reviews 2005; 48: 388–399
   PubMedGoogle Scholar
• Lucas SM, Rothwell NJ, Gibson RM. The role of inflammation in CNS injury and disease. British Journal of Pharmacology 2006; 147: 232–240
   PubMed Web of Science ®Google Scholar
• Morganti-Kossmann MC, Rancan M, Stahel PF, Kossmann T. Inflammatory response in acute traumatic brain injury: A doubleedged sword. Current Opinion in Critical Care 2002; 8: 101–105
   PubMedGoogle Scholar
• Allan SM, Rothwell NJ. Cytokine and acute neurodegeneration. Nature Reviews: Neuroscience 2001; 2: 734–744
   PubMed Web of Science ®Google Scholar
• Morganti-Kossmann MC, Satgunaseelan L, Bye N, Kossmann T. Modulation of immune response by head injury. Injury 2007; 38: 1392–1400
   PubMed Web of Science ®Google Scholar
• Gebhard F, Pfetsch H, Steinbach G, Strecker W, Kinzl L, Brückner UB. Is interleukin 6 an early marker of injury severity following major trauma in humans?. Archives of Surgery 2000; 135: 291–295
   PubMedGoogle Scholar
• Fishman D, Faulds G, Jeffery R, Mohamed-Ali V, Yudkin JS, Humphries S, Woo P. The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. Journal of Clinical Investigation 1998; 102: 1369–1376
   PubMed Web of Science ®Google Scholar
• Tsukamoto K, Haruta K, Shiba T, Emi M. Isolation and mapping of a polymorphic CA repeat sequence at the human interleukin 6 locus. Journal of Human Genetics 1998; 43: 71–72
   PubMed Web of Science ®Google Scholar
• Terry CF, Loukaci V, Green FR. Cooperative influence of genetic polymorphisms on interleukin 6 transcriptional regulation. Journal of Biological Chemistry 2000; 275: 18138–18144
   PubMed Web of Science ®Google Scholar
• Vasilescu A, Heath SC, Ivanova R, Hendel H, Do H, Mazoyer A, Khadivpour E, Goutalier FX, Khalili K, Rappaport J, et al. Genomic analysis of Th1-Th2 cytokine genes in an AIDS cohort: Identification of IL4 and IL10 haplotypes associated with the disease progression. Genes and Immunity 2003; 4: 441–449
   PubMed Web of Science ®Google Scholar
• Rivera-Chavez FA, Peters-Hybki DL, Barber RC, O’Keefe GE. Interleukin-6 promoter haplotypes and interleukin-6 cytokine responses. Shock 2003; 20: 218–223
   PubMed Web of Science ®Google Scholar
• Lahiri DK, Nurnberger JI, Jr. A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies. Nucleic Acids Research 1991; 19: 5444
   PubMed Web of Science ®Google Scholar
• Opdal SH, Rognum TO. The IL6 -174G/C polymorphism and sudden infant death syndrome. Human Immunology 2007; 68: 541–543
   PubMed Web of Science ®Google Scholar
• Waters RJ, Nicoll JAR. Genetic influences on outcome following acute neurological insults. Current Opinion in Critical Care 2005; 11: 105–110
   PubMed Web of Science ®Google Scholar
• McAllister TW, Flashman LA, Harker Rhodes C, Tyler AL, Moore JH, Saykin AJ, McDonald BC, Tosteson TD, Tsongalis GJ. Single nucleotide polymorphisms in ANKK1 and the dopamine D2 receptor gene affect cognitive outcome shortly after traumatic brain injury: A replication and extension study. Brain Injury 2008; 22: 705–714
   PubMed Web of Science ®Google Scholar
• Noé E, Ferri J, Colomer C, Moliner B, Chirivella J. APOE genotype and verbal memory recovery during and after emergence from post-traumatic amnesia. Brain Injury 2010; 24: 886–892
   PubMed Web of Science ®Google Scholar
• McDaniel DO, Hamilton J, Brock M, May W, Calcote L, Tee LY, Vick L, Newman DB, Vick K, Harrison S, et al. Molecular analysis of inflammatory markers in trauma patients at risk of postinjury complications. Journal of Trauma 2007; 63: 147–158
   PubMedGoogle Scholar
• Harding DR, Dhamrait S, Whitelaw A, Humphries SE, Marlow N, Montgomery HE. Does interleukin-6 genotype influence cerebral injury or developmental progress after preterm birth?. Pediatrics 2004; 114: 941–947
   PubMed Web of Science ®Google Scholar
• Miñambres E, Cemborain A, Sánchez-Velasco P, Gandarillas M, Diaz-Regañón G, Sánchez-González U, Leyva-Cobián F. Correlation between transcranial interleukin-6 gradient and outcome in patients with acute brain injury. Critical Care Medicine 2003; 31: 933–938
   PubMed Web of Science ®Google Scholar
• Gruol DL, Nelson TE. Physiological and pathological roles of interleukin-6 in the central nervous system. Molecula Neurobiology 1997; 15: 307–339
   PubMed Web of Science ®Google Scholar
• Thorns V, Walter GF, Licastro F. Effects of IL-6 and IL-1β on aFGF expression and exocitotoxicity in NT2N cells. Journal of Neuroimmunology 2002; 127: 22–29
   PubMed Web of Science ®Google Scholar
• Campbell IL, Abraham CR, Masliah E, Kemper P, Inglis JD, Oldstone MB, Mucke L. Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6. Proceedings of the National Academy of Sciences (USA) 1993; 90: 10061–10065
   PubMed Web of Science ®Google Scholar
• Singhal A, Baker AJ, Hare GM, Reinders FX, Schlichter LC, Moulton RJ. Association between cerebrospinal fluid interleukin-6 concentrations and outcome after severe human traumatic brain injury. Journal of Neurotrauma 2002; 19: 929–937
   PubMed Web of Science ®Google Scholar
• Winter CD, Pringle AK, Clough GF, Church MK. Raised parenchymal interleukin-6 levels correlate with improved outcome after traumatic brain injury. Brain 2004; 127: 315–320
   PubMed Web of Science ®Google Scholar
• Arand M, Melzner H, Kinzl L, Brückner UB, Gebhard F. Early inflammatory mediator response following isolated traumatic brain injury and other major trauma in humans. Langenbecks Archives of Surgery 2001; 386: 241–248
   PubMed Web of Science ®Google Scholar
• Kalabalikis P, Papazoglou K, Gouriotis D, Papadopoulos N, Kardara M, Papageorgiou F, Papadatos J. Correlation between serum IL-6 and CRP levels and severity of head injury in children. Intensive Care Medicine 1999; 25: 288–292
   PubMed Web of Science ®Google Scholar
• Roof RL, Hall ED. Gender differences in acute CNS trauma and stroke: Neuroprotective effects of estrogen and progesterone. Journal of Neurotrauma 2000; 17: 367–388
   PubMed Web of Science ®Google Scholar
• Jarrar D, Wang P, Cioffi WG, Bland KI, Chaudry IH. The female reproductive cycle is an important variable in the response to trauma-hemorrhage. American Journal of Physiology - Heart and Circulatory Physiology 2000; 279: 1015–1021
   PubMed Web of Science ®Google Scholar
• Sperry JL, Friese RS, Frankel HL, West MA, Cuschieri J, Moore EE, Harbrecht BG, Peitzman AB, Billiar TR, Maier RV, et al. Inflammation and the host response to injury investigators. Male gender is associated with excessive IL-6 expression following severe injury. Journal of Trauma 2008; 64: 572–579
   Google Scholar
• Wilson M, Montgomery H. Impact of genetic factors on outcome from brain injury. British Journal of Anaesthesia 2007; 99: 43–48
   PubMed Web of Science ®Google Scholar
• Nathoo N, Chetry R, van Dellen JR, Connolly C, Naidoo R. Apolipoprotein E polymorphism and outcome after closed traumatic brain injury: Influence of ethnic and regional differences. Journal of Neurosurgery 2003; 98: 302–306
   PubMed Web of Science ®Google Scholar
• Zhou W, Xu D, Peng X, Zhang Q, Jia J, Crutcher KA. Meta-analysis of APOE4 allele and outcome after traumatic brain injury. Journal of Neurotrauma 2008; 25: 279–290
   PubMed Web of Science ®Google Scholar