Evaluation of Adenovirus-Mediated Down-Regulation of Connective Tissue Growth Factor on Postoperative Wound Healing After Experimental Glaucoma Surgery

References

• The Fluorouracil Filtering Surgery Study Group. Fluorouracil Filtering Surgery Study one-year follow-up. Am J Ophthalmol 1989;108:625–635.
   Google Scholar
• The Fluorouracil Filtering Surgery Study Group. Three-year follow-up of the Fluorouracil Filtering Surgery Study. Am J Ophthalmol 1993;115:82–92.
   Google Scholar
• Robin AL, Ramakrishnan R, Krishnadas R, Smith SD, Katz JD, Selvaraj S, et al. A long-term dose-response study of mitomycin in glaucoma filtration surgery. Arch Ophthalmol 1997;115:969–974.
   PubMed Web of Science ®Google Scholar
• Crowston JG, Akbar AN, Constable PH, Occleston NL, Daniels JT, Khaw PT. Antimetabolite-induced apoptosis in Tenon’s capsule fibroblasts. Invest Ophthalmol Vis Sci 1998;39:449–454.
   PubMed Web of Science ®Google Scholar
• Mietz H, Addicks K, Bloch W, Krieglstein GK. Long-term intraocular toxic effects of topical mitomycin C in rabbits. J Glaucoma 1996;5:325–333.
   PubMed Web of Science ®Google Scholar
• Gedde SJ, Schiffman JC, Feuer WJ, Herndon LW, Brandt JD, Budenz DL; Tube versus Trabeculectomy Study Group. Treatment outcomes in the Tube Versus Trabeculectomy (TVT) study after five years of follow-up. Am J Ophthalmol 2012;153:789–803.e2.
   Google Scholar
• Perkins TW, Faha B, Ni M, Kiland JA, Poulsen GL, Antelman D, et al. Adenovirus-mediated gene therapy using human p21WAF-1/Cip-1 to prevent wound healing in a rabbit model of glaucoma filtration surgery. Arch Ophthalmol 2002;120:941–949.
   PubMed Web of Science ®Google Scholar
• Heatley G, Kiland J, Faha B, Seeman J, Schlamp CL, Dawson DG, et al. Gene therapy using p21WAF-1/Cip-1 to modulate wound healing after glaucoma trabeculectomy surgery in a primate model of ocular hypertension. Gene Ther 2004;11:949–955.
   PubMed Web of Science ®Google Scholar
• Duncan MR, Frazier KS, Abramson S, Williams S, Klapper H, Huang X, et al. Connective tissue growth factor mediates transforming growth factor beta-induced collagen synthesis: down-regulation by cAMP. FASEB J 1999;13:1774–1786.
   PubMed Web of Science ®Google Scholar
• Grotendorst GR. Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts (review). Cytokine Growth Factor Rev 1997;8:171–179.
   PubMedGoogle Scholar
• Ihn H. Pathogenesis of fibrosis: role of TGF-beta and CTGF. Curr Opin Rheumatol 2002;14:681–685.
   PubMed Web of Science ®Google Scholar
• Lau LF, Lam SC. The CCN family of angiogenic regulators: the integrin connection. Exp Cell Res 1999;248:44–57.
   PubMed Web of Science ®Google Scholar
• Mead AL, Wong TT, Cordeiro MF, Anderson IK, Khaw PT. Evaluation of anti-TGF-beta2 antibody as a new postoperative anti-scarring agent in glaucoma surgery. Invest Ophthalmol Vis Sci 2003;44:3394–3401.
   PubMed Web of Science ®Google Scholar
• Cordeiro MF, Mead A, Ali RR, Alexander RA, Murray S, Chen C, et al. Novel antisense oligonucleotides targeting TGF-beta inhibit in vivo scarring and improve surgical outcome. Gene Ther 2003;10:59–71.
   PubMed Web of Science ®Google Scholar
• Sherwood MB. A sequential, multiple-treatment, targeted approach to reduce wound healing and failure of glaucoma filtration surgery in a rabbit model (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc 2006;104:478–492.
   PubMedGoogle Scholar
• Wong TT, Mead AL, Khaw PT. Matrix metalloproteinase inhibition modulates post-operative scarring after experimental glaucoma filtration surgery. Invest Ophthalmol Vis Sci 2003;44:1097–1103.
   PubMed Web of Science ®Google Scholar
• Esson DW, Neelakantan A, Iyer SA, Blalock TD, Balasubramanian L, Grotendorst GR, et al. Expression of connective tissue growth factor after glaucoma filtration surgery in a rabbit model. Invest Ophthalmol Vis Sci 2004;45:485–491.
   PubMed Web of Science ®Google Scholar
• Shah M, Foreman DM, Ferguson MW. Neutralising antibody to TGF-beta 1,2 reduces cutaneous scarring in adult rodents. J Cell Sci 1994;107:1137–1157.
   PubMed Web of Science ®Google Scholar
• Perbal B. CCN proteins: multifunctional signalling regulators. Lancet 2004;363:62–64.
   PubMed Web of Science ®Google Scholar
• Rachfal AW, Brigstock DR. Structural and functional properties of CCN proteins. Vitam Horm 2005;70:69–103.
   PubMed Web of Science ®Google Scholar
• Bradham DM, Igarashi A, Potter RL, Grotendorst GR. Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10. J Cell Biol 1991;114:1285–1294.
   PubMed Web of Science ®Google Scholar
• Brigstock DR, Steffen CL, Kim GY, Vegunta RK, Diehl JR, Harding PA. Purification and characterization of novel heparin-binding growth factors in uterine secretory fluids. Identification as heparin-regulated Mr 10,000 forms of connective tissue growth factor. J Biol Chem 1997;272:20275–20282.
   Google Scholar
• Frazier K, Williams S, Kothapalli D, Klapper H, Grotendorst GR. Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor. J Invest Dermatol 1996;107:404–411.
   PubMed Web of Science ®Google Scholar
• Babic AM, Chen CC, Lau LF. Fisp12/mouse connective tissue growth factor mediates endothelial cell adhesion and migration through integrin alphavbeta3, promotes endothelial cell survival, and induces angiogenesis in vivo. Mol Cell Biol 1999;19:2958–2966.
   PubMed Web of Science ®Google Scholar
• Shimo T, Nakanishi T, Nishida T, Asano M, Kanyama M, Kuboki T, et al. Connective tissue growth factor induces the proliferation, migration, and tube formation of vascular endothelial cells in vitro, and angiogenesis in vivo. J Biochem 1999;126:137–145.
   PubMed Web of Science ®Google Scholar
• Igarashi A, Okochi H, Bradham DM, Grotendorst GR. Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair. Mol Biol Cell 1993;4:637–645.
   PubMed Web of Science ®Google Scholar
• Kireeva ML, Latinkic BV, Kolesnikova TV, Chen CC, Yang GP, Abler AS, et al. Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during development. Exp Cell Res 1997;233:63–77.
   PubMed Web of Science ®Google Scholar
• Crean JK, Finlay D, Murphy M, Moss C, Godson C, Martin F, et al. The role of p42/44 MAPK and protein kinase B in connective tissue growth factor induced extracellular matrix protein production, cell migration, and actin cytoskeletal rearrangement in human mesangial cells. J Biol Chem 2002;277:44187–44194.
   PubMed Web of Science ®Google Scholar
• Igarashi A, Nashiro K, Kikuchi K, Sato S, Ihn H, Grotendorst GR, et al. Significant correlation between connective tissue growth factor gene expression and skin sclerosis in tissue sections from patients with systemic sclerosis. J Invest Dermatol 1995;105:280–284.
   PubMed Web of Science ®Google Scholar
• Igarashi A, Nashiro K, Kikuchi K, Sato S, Ihn H, Fujimoto M, et al. Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid, and other fibrotic skin disorders. J Invest Dermatol 1996;106:729–733.
   PubMed Web of Science ®Google Scholar
• Chen Y, Abraham DJ, Shi-Wen X, Pearson JD, Black CM, Lyons KM, et al. CCN2 (connective tissue growth factor) promotes fibroblast adhesion to fibronectin. Mol Biol Cell 2004;15:5635–5646.
   PubMed Web of Science ®Google Scholar
• Shi-wen X, Stanton LA, Kennedy L, Pala D, Chen Y, Howat SL, et al. CCN2 is necessary for adhesive responses to transforming growth factor-beta1 in embryonic fibroblasts. J Biol Chem 2006;281:10715–10726.
   PubMed Web of Science ®Google Scholar
• Cordeiro MF, Gay JA, Khaw PT. Human anti-transforming growth factor-beta2 antibody: a new glaucoma anti-scarring agent. Invest Ophthalmol Vis Sci 1999;40:2225–2234.
   PubMed Web of Science ®Google Scholar
• Yang JG, Sun NX, Cui LJ, Wang XH, Feng ZH. Adenovirus-mediated delivery of p27(KIP1) to prevent wound healing after experimental glaucoma filtration surgery. Acta Pharmacol Sin 2009;30:413–423.
   PubMed Web of Science ®Google Scholar