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Current Eye Research Volume 6, 1987 - Issue 5
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Original Article

Treatment of corneal xerophthalmia in rabbits with micromolar doses of topical retinoic acid

John L. Ubels Departments of Physiology, Medical College of Wisconsin, Milwaukee, WI, 53226, USA; Departments of Ophthalmology, Medical College of Wisconsin, Milwaukee, WI, 53226, USA
,
Vivian Rismondo Departments of Physiology, Medical College of Wisconsin, Milwaukee, WI, 53226, USA
&
Henry F. Edelhauser Departments of Physiology, Medical College of Wisconsin, Milwaukee, WI, 53226, USA; Departments of Ophthalmology, Medical College of Wisconsin, Milwaukee, WI, 53226, USA
Pages 735-737 | Received 22 Dec 1986, Accepted 02 Mar 1987, Published online: 02 Jul 2009

References

  • Pirie A. Effects of locally applied retinoic acid on xerophthalmia in the rat. Exp. Eye Res. 1977; 25: 297–302
  • Sommer A., Emran N. Topical retinoic acid in the treatment of corneal xerophthalmia. Am. 3 Ophthalmol. 1978; 86: 615–617
  • Van Horn D. L., DeCarlo J. D., Schutten W. H., Hyndiuk R. A. Topical retinoic acid in the treatment of experimental xerophthalmia in the rabbit. Arch Ophthalmol. 1981; 99: 317–321
  • Ubels J. L., Edelhauser H. F., Austin K. H. Healing of experimental corneal wounds treated with topically applied retinoids. Am. J. Ophthalmol. 1983; 95: 353–358
  • Nelson J. D., Havener V. R., Cameron J. D. Cellulose acetate impressions of the ocular surface: dry eye states. Arch. Ophthalmol. 1983; 101: 1869–1872
  • Hatchell D. L., Sommer A. Detection of ocular surface abnormalities in experimental vitamin A deficiency. Arch. Ophthalmol. 1984; 102: 1389–1393
  • Tseng S. C.G., Maumenee A. E., Stark W. J., Maumenee I. H., Jensen A. D., Green W. R., Kenyon K. R. Topical retinoid treatment for various dry eye disorders. Ophthalmology 1985; 92: 717–727
  • Wright P. Topical retinoic acid therapy for disorders of the outer eye. Trans. Ophthalmol. Soc. U.K. 1985; 104: 869–874
  • Sommer A. Treatment of corneal xerophthalmia with topical retinoic acid. Am. 3. Ophthalmol. 1983; 95: 349–352
  • Ubels J. L., Edelhauser H. F., Foley K. M., Liao J. C., Gressel P. The efficacy of retinoic acid ointment for treatment of xerophthalmia and corneal epithelial wounds. Curr. Eye Res. 1985; 4: 1049–1057
  • Fraunfelder F. T., LaBraico J. M., Meyer S. M. Adverse ocular reactions possible associated with isotretinoin. Am. 3. Ophthalmol. 1985; 100: 534–537
  • Leyden J. J., Shalita A. R. Rational therapy for acne vulgaris: an update on topical treatment. J. Am. Acad. Dermatol. 1986; 15: 907–914
  • Sporn M. B., Dunlop N. M., Newton D. L., Hinterson W. R. Relationship between structure and activity of retinoids. Nature 1976; 263: 110–113
  • Ubels J. L., Rismondo V., Foley K. M. Retinol secretion by the lacrimal gland. Invest. Ophthalmol. Vis. Sci. 1986; 27: 1261–1268

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