Pathogenesis of corneal epithelial defects: Role of plasminogen activator

References

• Kenyon K. R. Decision-making in the therapy of external eye disease: noninfected corneal ulcers. Ophthalmology 1982; 89: 44–51
   PubMed Web of Science ®Google Scholar
• Berman M., Kenyon K., Hayashi K., L'llernault N. The pathogenesis of epithelial defects and stromal ulceration. “The Cornea: Transactions of the World Congress on the Cornea III”, H. D. Cavanagh. Raven Press, New York 1988; 35–43
   Google Scholar
• Berman M. B. Collagenase and conical ulceration. “Collagenase in Normal and Pathological Connective Tissues”, D. E. Woolley, J. M. Evanson. John Wiley, ChichesterUK 1980; 141–174
   Google Scholar
• Berman M. The pathogenesis of corneal epithelial defects. Acta Ophthalmol. 1989; 67: 55–64, (Suppl. 192V)
   Google Scholar
• Berman M., Manseau E., Law M., Aiken D. Ulceration is correlated with degradation of fibrin and fibronectin at the corneal surface. Invest. Ophthalmol. Vis. Sci. 1983; 24: 1358–1366
   PubMed Web of Science ®Google Scholar
• Berman M., Leary R., Gage J. Evidence for a role of the plasminogen activator-plasmin system in corneal ulceration. Invest. Ophthalmol. Vis. Sci. 1980; 19: 1204–1221
   PubMed Web of Science ®Google Scholar
• Wang H.-M., Berman M., Law M. Latent and active plasminogen activator in corneal ulceration. Invest. Ophthalmol. Vis. Sci. 1985; 26: 511–524
   PubMed Web of Science ®Google Scholar
• Danø K., Andreasen P., Grøndahl-Hansen J., Kristensen P., Nielsen L., Skriver L. Plasminogen activators, tissue degradation, and cancer. Adv. Cancer Res. 1985; 44: 139–266
   PubMed Web of Science ®Google Scholar
• Saksela O., Rifkin D. Cell-associated plasminogen activation: regulation and physiological functions. Annu. Rev. Cell Biol. 1988; 4: 93–126
   PubMedGoogle Scholar
• Lijnen H., Collen D. Mechanisms of plasminogen activation by mammalian plasminogen activators. Enzyme 1988; 40: 90–96
   PubMedGoogle Scholar
• Pepper M-S., Vassalli J-D., Montesano R., Orci L. Urokinase-type plasminogen activator is induced in migrating capillary endothelial cells. J. Cell Biol. 1987; 105: 2535–2541
   PubMed Web of Science ®Google Scholar
• Vassalli J.-D., Belin D. Amiloride selectively inhibits the urokinase type of plasminogen activator. FEBS Lett. 1987; 214: 187–191
   PubMed Web of Science ®Google Scholar
• Saksela O. Radial caseinolysis in agarose: a simplified method for detection of plasminogen activator in the presence of inhibitor substances and serum. Anal. Biochem. 1981; 111: 276–282
   PubMed Web of Science ®Google Scholar
• Burnette W. “Western Blotting”: electrophoretic transfer of proteins from sodium dodecylsulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal. Biochem. 1981; 112: 195–205
   PubMed Web of Science ®Google Scholar
• Nishida T., Nakagawa S., Watanabe K., Yamada K., Otori T., Berman M. A peptide from fibronectin cell-binding domain inhibits attachment of epithelial cells. Invest. Ophthalmol. Vis. Sci. 1988; 29: 1820–1825
   PubMed Web of Science ®Google Scholar
• Watanabe K., Berman M. Mechanisms of persistent epithelial defect formation: peptide from the cell-binding domain (GRGDS) inhibits corneal epithelial cell migration. Invest. Ophthalmol. Vis. Sci. 1988; 29: 192, Suppl.)
   Google Scholar
• Berman M., Wang H.-M., Wood J., Law M. Plasmin regulates corneal collagenase secretion by degrading cell surface/matrix fibronectin. Invest. Ophthalmol. Vis. Sci. 1984; 25: 6, Suppl.
   Google Scholar
• Pandolfi M., Lantz E. Partial purification and characterization of keratokinase, the fibrinolytic activator of the cornea. Exp. Eye Res. 1979; 29: 563–571
   PubMedGoogle Scholar
• Chan K. Release of plasminogen activator by cultured corneal epithelial cells during differentiation and wound closure. Exp. Eye Res. 1986; 42: 417–431
   PubMed Web of Science ®Google Scholar
• Haber E., Quertermous T., Matsuda G., Runge M. Innovative approaches to plasminogen activator therapy. Science 1989; 243: 51–56
   PubMed Web of Science ®Google Scholar
• Geanon J., Tripathi B., Tripathi R. The localization of tissue plasminogen activator by a monoclonal antibody in human and monkey eyes. Invest. Ophthalmol. Vis. Sci. 1987; 28: 108, Suppl.
   Google Scholar
• Geanon J., Tripathi B., Tripathi R., Barlow G. Tissue plasminogen activator in avascular tissues of the eye: a quantitative study of its activity in the cornea, lens, and aqueous and vitreous humors of dog, calf and monkey. Exp. Eye Res. 1987; 44: 55–63
   PubMedGoogle Scholar
• Park J., Tripathi B., Tripathi R. Distribution of urokinase-like plasminogen activator in the human eye. Invest. Ophthalmol. Vis. Sci. 1988; 29: 207, Suppl.
   Google Scholar
• Blasi F., Vassalli J.-D., Dan K. Urokinase-type plasminogen activator: proenzyme, receptor and inhibitors. J. Cell Biol. 1987; 104: 801–804
   PubMed Web of Science ®Google Scholar
• Liotta L., Rao C., Barsky S. Tumor invasion and the extracellular matrix. Lab. Invest. 1983; 49: 636–649
   PubMed Web of Science ®Google Scholar
• Kleyman T., Cragoe E., Jr. Amiloride and its analogs as tools in the study of ion transport. J. Membrane Biol. 1988; 105: 1–21
   PubMed Web of Science ®Google Scholar
• Berman M., Hayashi K., Young E., Pease S., Smith D., El-Ghatit A., Askew M., Cragoe E. J., Jr. Urokinase-like plasminogen activator, corneal epithelial migration and defect formation. Invest. Ophthalmol. Vis. Sci. 1989; 30: 2, Suppl.
   Google Scholar
• Gilboa N., Villannueva G., Fenton J. Inhibition of fibrinolytic enzymes by thrombin inhibitors. Enzyme 1988; 40: 144–148
   PubMedGoogle Scholar
• Morioka S., Lazarus J., Baird L., Jensen P. Migrating keratinocytes express urokinase-type plasminogen activator. J. Invest. Dermatol. 1987; 88: 418–423
   PubMedGoogle Scholar
• Grøndahl-Hansen J., Lund L., Ralfkiaer E., Ottevanger V., Danø K. Urokinase- and tissue-type plasminogen activators in keratinocytes during wound reepithelialization in vivo. J. Invest. Dermatol. 1988; 90: 790–795
   PubMed Web of Science ®Google Scholar
• Sprengers E., Kluft C. Plasminogen activator inhibitors. Blood 1987; 69: 381–387
   PubMed Web of Science ®Google Scholar
• Pollanen J., Hedman K., Nielsen L., Dan0 K., Vaheri A. Ultrastructural localization of plasma membrane-associated urokinase-like plasminogen activator at focal contacts. J. Cell Biol. 1988; 106: 87–95
   PubMed Web of Science ®Google Scholar
• Quigley J., Gold L., Schwimmer R., Sullivan L. Limited cleavage of cellular fibronectin by plasminogen activator purified from transformed cells. Proc. Natl. Acad. Sci. USA 1987; 84: 2776–2780
   PubMedGoogle Scholar
• Sullivan L., Quigley J. An anticatalytic monoclonal antibody to avian plasminogen activator: its effect on behavior of RSV-transformed chick fibroblasts. Cell 1986; 45: 905–915
   PubMed Web of Science ®Google Scholar
• Pouyssegur J. The growth factor-activatable Na+/H+ exchange system: a genetic approach. “Oncogenes and Growth Factors”, R. Bradshaw, S. Prentis, 1987; 292–297
   Google Scholar
• Gipson I., Spurr-Michaud S., Tisdale A., Zieske J. Dynamics of hemidesmosome and focal contact formation during corneal epithelial wound healing. Invest. Ophthalmol. Vis. Sci. 1989; 30: 383, Suppl
   Google Scholar
• Salonen E.-M., Tervo T., Torma E., Tarkkanen A., Vaheri A. Plasmin in tear fluid of patients with corneal ulcers: basis for new therapy. Acta Ophthalmol 1987; 65: 3–12
   PubMed Web of Science ®Google Scholar
• Chen W.-T., Chen J-M., Parsons S., Parsons J. Local degradation of fibronectin at the sites of expression of the transforming gene product pp60src. Nature 1985; 316: 156–158
   PubMed Web of Science ®Google Scholar
• Bishop J. M. “Cancer Biology.”. W.H. Freeman, New York 1985; 66–76
   Google Scholar
• Hunter T. Oncogenes and growth control. “Oncogenes and Growth Factors”, R. Bradshaw, S. Prentis. Elsevier, New York 1987; 135–142
   Google Scholar
• Burridge K., Fath K., Kelly T., Nuckolls G., Turner C. Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton. Annu. Rev. Cell Biol. 1988; 4: 487–525
   PubMedGoogle Scholar
• Stickel S., Wang Y.-L. Synthetic peptide GRGDS induces dissociation of alpha-actinin and vinculin from the sites of focal contacts. J. Cell Biol. 1988; 107: 1231–1239
   PubMed Web of Science ®Google Scholar
• Storm O. Fibrinolytic activity in human tears. Scand. J. Clin. Lab. Invest. 1955; 7: 55–58
   PubMed Web of Science ®Google Scholar
• Thorig L., Wijngaards G., Van Haeringen N. Immunological characterization and possible origin of plasminogen activator in human tear fluid. Ophthalmic Res. 1983; 15: 268–276
   PubMed Web of Science ®Google Scholar
• Lantz E., Pandolfi M. Fibrinolysis in cornea and conjunctiva: evidence of two types of activators. Graefes Arch. Clin. Exp. Ophthalmol. 1986; 224: 393–396
   PubMed Web of Science ®Google Scholar
• Liu J., Hong B.-S., Price J. Correlation of corneal epithelial wound healing and plasminogen activator activity in rabbit tear. Invest. Ophthalmol. Vis. Sci. 1987; 28: 330, Suppl.
   PubMedGoogle Scholar
• Hayashi K., Sueishi K. Fibrinolytic activity and species of plasminogen activator in human tears. Exp. Eye Res. 1988; 46: 131–137
   PubMedGoogle Scholar
• Tozser J., Berta A., Punyiczk M. Plasminogen activator activity and plasminogen-independent amidolytic activity in tear fluid from healthy persons and from patients with anterior segment inflammation. Clin. Chim. Acta. 1989; 183: 323–331
   PubMed Web of Science ®Google Scholar
• Pandolfi M., Kwaan H. Fibrinolysis in the anterior segment of the eye. Arch. Ophthalmol. 1967; 77: 99–104
   PubMedGoogle Scholar
• Park J., Tripathi R., Barlow G., Tripathi B. Tissue plasminogen activator in trabecular endothelium and its role in traumatic hyphema. Invest. Ophthalmol. Vis. Sci. 1986; 27: 165, Suppl.)
   Google Scholar
• Tripathi R., Park J., Tripathi B., Millard C. Tissue plasminogen activator in human aqueous humor and its possible therapeutic significance. Am. J. Ophthalmol. 1988; 106: 719–722
   PubMedGoogle Scholar
• Shuman M., Polansky J., Merkel C., Alvarado J. Tissue plasminogen activator in cultured human trabecular meshwork cells. Invest. Ophthalmol. Vis. Sci. 1988; 29: 401–405
   PubMedGoogle Scholar