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Current Eye Research Volume 10, 1991 - Issue sup1
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Original Article

Emergence of cross-resistant herpes simplex virus following topical drug therapy in rabbit keratitis

C. Fardcau Unité de Recherches d'Ophtalmologie, INSERM U 86, Hotel-Dieu, Paris, 75004
,
M. Langlois Laboratoire d'Etudes des Maladies Virales et Laboratoire de Virologie du CHU, Lyon Cedex 08, 69373, France
,
B. Mathys Unité de Recherches d'Ophtalmologie, INSERM U 86, Hotel-Dieu, Paris, 75004
,
P. Rafales Unité de Recherches d'Ophtalmologie, INSERM U 86, Hotel-Dieu, Paris, 75004
,
F. Nugier Laboratoire d'Etudes des Maladies Virales et Laboratoire de Virologie du CHU, Lyon Cedex 08, 69373, France
,
V. Godard Unité de Recherches d'Ophtalmologie, INSERM U 86, Hotel-Dieu, Paris, 75004
,
M. Aymard Laboratoire d'Etudes des Maladies Virales et Laboratoire de Virologie du CHU, Lyon Cedex 08, 69373, France
&
J. Denis Unité de Recherches d'Ophtalmologie, INSERM U 86, Hotel-Dieu, Paris, 75004
 show all
Pages 151-158 | Received 27 Aug 1990, Accepted 21 Mar 1991, Published online: 02 Jul 2009

References

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  • Coleman V. R., Tsu E., Jawetz F. “Treatment-Resistance” to idoxuridine in herpetic keratitis. Soc. Exp. Biol. Med. 1968; 120: 761–765
  • Field J. H. Review. Persistent herpes simplex virus infection and mechanisms of virus drug resistance. Eur. J. Clin. Microbiol. Infect. Dis. 1989; 8: 671–680
  • Denis J., Langlois M., Elkaim M., Amiel C., Aymard M., Huraux J. M. HSV1 strain sensitivity in experimental rabbit keratitis : evolution under repeated topical administrations. Curr. Eye Res. 1987; 6: 39–45
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  • McLaren C. Drug resistance patterns of herpes simplex virus isolates from patients treated with acyclovir. Antimicrob. Agents Chemother. 1985; 28: 740–744
  • Charles S. J., Gray J. J. Ocular herpes simplex virus infections: reduced sensitivity to acyclovir in primary disease. Br. J. Ophthalmol. 1990; 74: 286–288
  • Yoshida T., Suzutani T., Azuma M. Study on the apparent resistant strains of herpes simplex virus type 1 against 9-β-D-Arabinofuranosyladenine. Tohoku J. Exp. Med. 1988; 156: 279–290
  • Prusoff W. H., Fisher P. H. Basis for the selective antiviral and antitumour activity of pyrimidine nucleoside analogues. Nucleoside Analogues Chemistry, Biology, and Medical Applications, R. T. Walker, E. De Clercq, F. Eckstein. Plenum Press, New York 1979; 101–102
  • Larder B. A., Darby G. Susceptibility to other antiherpes drugs of pathogenic variants of herpes simplex virus selected for resistance to acyclovir. Antimicrob. Agents Chemother. 1986; 29: 894–898

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