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Current Eye Research Volume 11, 1992 - Issue sup1
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Original Article

Humoral immune response against the S-antigen/TNFα common epitope in rat EAU suppressed by the monoclonal antibody S2D2

Yvonne de Kozak Laboratoire d'Immunopathologie de l'Oeil, INSERM U 86, Paris, France
,
Rainer H. Stiemer Laboratoire d'Immunopathologie de l'Oeil, INSERM U 86, Paris, France
,
Massoud Mirshahi Laboratoire d'Immunopathologie de l'Oeil, INSERM U 86, Paris, France
,
Rainer W. Frank Center of Molecular Biology, University of Heidelberg, Germany
,
Marc de Smet NIH, NEI, Bethesda, MD, USA
&
Jean-Pierre Faure Laboratoire d'Immunopathologie de l'Oeil, INSERM U 86, Paris, France
Pages 119-127 | Received 02 Jan 1992, Accepted 26 May 1992, Published online: 02 Jul 2009

References

  • Donoso L. A., Merryman C. F., Sery T. W., Shinohara T., Dietzschold B., Smith A., Kalsow C. M. S-antigen: characterization of a pathogenic epitope which mediates experimental autoimmune uveitis and pinealitis in Lewis rats. Curr. Eye Res. 1987; 6: 1151–1159
  • Donoso L. A., Yamaki K., Merryman C. F., Shinohara T., Yue S., Sery T. W. Human S-antigen: characterisation of uveitopathogenic sites. Curr. Eye Res. 1988; 2: 1077–1085
  • Merryman C. F., Donoso L. A., Zhang X, Heber-Katz E., Gregerson D. Characterization of a new, potent, immunopathogenic epitope in S-antigen that elicits T cells expressing Vβ8 and Vα2-like genes. J. Immunol. 1991; 146: 75–80
  • Gregerson D. S., Merryman C. F., Obritsh W. F., Donoso L. A. Identification of a potent new pathogenic site in human retinal S-antigen which induces experimental autoimmune uveoretinitis in Lewis rats. Cell. Immunol. 1990; 128: 209–219
  • Stiemer R. H., Westenfelder U., Gausepohl H., Mirshahi M., Gund A., Frank R. W., Männel D. N. A common epitope on human tumor necrosis factor alpha and the autoantigen, “S-antigen/arrestin” induces TNF alpha production. J. Autoimmun. 1992; 5: 15–26
  • de Kozak Y., Mirshahi M., Boucheix C., Faure J. P. Inhibition of experimental autoimmune uveoretinitis in rats with S-antigen specific monoclonal antibodies. Eur. J. Immunol. 1985; 15: 1107–1111
  • De Kozak Y., Mirshahi M., Boucheix C., Faure J. P. Prevention of experimental autoimmune uveoretinitis by active immunization with autoantigen-specific monoclonal antibodies. Eur. J. Immunol. 1987; 17: 541–547
  • De Kozak Y., Mirshahi M., Boucheix C., Faure J. P. Inhibition of S-antigen-induced experimental autoimmune uveoretinitis by active immunization against anti-idiotypic antibody to S-antigen epitope. Regional Immunol. 1992, In press
  • Mirshahi M, de Kozak Y, Gregerson D. S., Stiemer R., Boucheix C., Faure J. P. Genetic susceptibility of rat strains to induction of EAU in relation with the immune response to a particular epitope of S-antigen. Ocular Immunology Today, M. Usui, S. Ohno, K. Aoki. Excerpta Medica, Amsterdam 1990; 195–198
  • Perrot J. Y., Boucheix C., Mirshahi M., Kazatchkine M., Bariety J. Des anticorps monoclonaux dirigés contre les antigènes de surface des lymphocytes et de cellules sanguines ou médullaires reconnaissent des constituants distincts du néphron dans le cortex du rein normal. Nephrologie 1984; 5: 53–57
  • de Kozak Y., Mirshahi M., Boucheix C., Faure J. P. Modulation of experimental autoimmune uveoretinitis by adoptive transfer of cells from rats immunized with anti-S-antigen monoclonal antibody. Regional Immunol. 1989; 2: 311–320
  • Dorey C., Cozette J., Faure J. P. A simple and rapid method for isolation of retinal S-antigen. Ophthalmic Res. 1982; 14: 249–255
  • de Kozak Y. Regulation of retinal autoimmunity via the idiotypic network. Curr. Eye Res. 1990; 9: 193–200
  • Stiemer R. H., Westenfelder U., de Kozak Y., Gausepohl H., Mirshahi M., Frank R. W., Faure J. P., Mannel D. N. Cytokine induction by immunomodulatory epitopes in S-antigen and tumor necrosis factor alpha. Curr. Eye Res. 1992; 11(Suppl.)197–202
  • Scheurich P., Thomas B., Ucer U., Pfizenmaier K. Immunoregulatory activity of recombinant human tumor necrosis factor (TNF)-α: induction of TNF receptors on human T cells and TNF-α mediated enhancement of T cell responses. J. Immunol. 1987; 138: 178–1790
  • Jelinek D. F., Lipski P. E. Enhancement of human B cell proliferation and differentiation by tumor necrosis factor-α and interleukin-1. J. Immunol. 1987; 139: 2970–2976
  • Becker J. C., Kolanus W., Lonneman C., Schmitt R. E. Human natural killer clones enhances in vitro antibody production, tumor necrosis factor alpha and gamma interferon. Scand. J. Immunol. 1990; 32: 153–162
  • Brosnan C. F., Selmaj K., Raine C. S. Hypothesis: a role for tumor necrosis factor in immunemediated demyelination and its relevance to multiple sclerosis. J. Neuroimmunol. 1988; 18: 87–94
  • Ruddle N. H., Bergman C. M., McGrath K. M., Lindenheld E. G., Grunnet M. L., Padua S. J., Clark R. B. An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encepholomyelitis. J. Exp. Med. 1990; 172: 1193–1200

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