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Original Article

Suppression of experimental autoimmune uveoretinitis by prazosin, an α1-adrenergic receptor antagonist

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Pages 135-140 | Received 02 Jan 1992, Accepted 23 Mar 1992, Published online: 02 Jul 2009

References

  • Caspi R. R., Roberge F. G., McAllister C., El Said M., Kuwabara T., Gery I., Hanna E., Nussenblatt R. B. T cell lines mediating experimental autoimmune uveoretinitis (EAU) in the rat. J. Immunol. 1986; 136: 928–933
  • Chan C. C., Hooks J. J., Nussenblatt R. B., Detrick B. Expression of Ia antigen on retinal pigment epithelium in experimental autoimmune uveoretinitis. Curr. Eye Res. 1986; 5: 325–330
  • Fujikawa L. S., Chan C. C., McAllister C., Gery I., Hooks J. J., Detrick B., Nussenblatt R. B. Retinal vascular endothelium expresses fibronectin and class II histocompatibility complex antigens in experimental autoimmune uveitis. Cell. Immunol. 1988; 106: 139–150
  • Roberge F. G., Caspi R. R., Nussenblatt R. B. Glial retinal Mûller cells produce IL1 activity and have a dual role in regulation of autoimmune T lymphocytes: antigen presentation manifested after removal of suppressive activity. J. Immunol. 1988; 140: 2193–2196
  • de Kozak Y., Thillaye B., Renard G., Faure J. P. Hyperacute form of experimental autoimmune uveoretinitis in Lewis rats; electron microscopic study. Graefes Arch. Clin. Exp. Ophthalmol. 1978; 208: 135–142
  • Dua H. S., McKinnon A., McMenmin P. G., Forrester J. V. Ultrastructural pathology of the “barrier site” in experimental autoimmune uveitis and experimental autoimmune pinealitis. Br. J. Ophthalmol. 1991; 75: 391–397
  • de Kozak Y., Sainte-Laudy J., Beneveniste J., Faure J. P. Evidence for immediate hypersensitivity phenomena in experimental autoimmune uveoretinitis. Eur. J. Immunol. 1981; 11: 612–617
  • de Kozak Y., Sakai J., Sainte-Laudy J., Beneveniste J., Faure J. P. Pharmological modulation of IgE-dependent mast cell degranulation in experimental autoimmune uveoretinitis. Jpn. J. Ophthalmol. 1983; 27: 598–608
  • Dorey C., Cozette, Faure J. P. A simple and rapid method for isolation of retinal S-antigen. Ophthalmic Res. 1982; 14: 249–255
  • de Kozak Y., Mirshahi M., Boucheix C., Faure J. P. Inhibition of experimental autoimmune uveoretinitis in rats with S-antigen specific monoclonal antibodies. Eur. J. Immunol. 1985; 15: 1107–1111
  • de Kozak Y., Mirshahi M, Boucheix C., Faure J. P. Modulation of experimental autoimmune uveoretinitis by adoptive transfer of cells from rats immunized with anti-S-antigen monoclonal antibody. Reg. Immunol. 1989; 2: 311–320
  • Goldmuntz E. A., Brosnan C. F., Norton W. T. Prazosin treatment suppresses clinical increased vascular permeability in both acute and passively transferred experimental autoimmune encephalomyelitis in the Lewis rat. J. Immunol. 1986; 137: 3444–3450
  • Brosnan C. F., Goldmuntz E. A., Cammer W., Factor S. M., Bloom B. R., Norton W. T. Prazosin an α1-adrenergic receptor antagonist, suppresses experimental autoimmune encephalomyelitis in the Lewis rat. Proc. Natl. Acad. Sci. USA 1985; 82: 5915–5919
  • Brosnan C. F., Sacks H. J., Goldshmidt R. C., Goldmuntz E. A., Norton W. T. Prazosin treatment during the effector stage of disease suppresses experimental autoimmune encephalomyelitis in the Lewis rat. J. Immunol. 1986; 137: 3451–3456
  • Norton W. T., Brosnan C. F., Cammer W., Goldmuntz E. A. Mechanism and suppression of inflammatory demyelination. Acta Neurobiol. Exp. 1990; 50: 225–235
  • Gershon R. K., Askenase P. W., Gershon M. D. Requirement for vasoactive amines in delayed-type hypersensitivity. J. Exp. Med. 1975; 142: 732–747
  • Askenase P. W., Van Louren H. Delayed-type hypresensitivity: activation of mast cells antigen-specific T-cell factors initiates the cascade of cellular interactions. Immunol. Today 1983; 4: 259–261
  • Joris I., Majno G. Endothelial changes induced by arterial spasm. Am. J. Pathol. 1981; 105: 346–358
  • Weiner N. Drugs that inhibit adrenergic nerves and block adrenergic receptors. The Pharmacological Basis of Therapeutics, L. S. Goodman, A. G. Gilman. Mac Millan, New York 1985; 181–214
  • Zarbin M. A., Wamsley J. K., Palacios J. M., Kuhar M. J. Autoradiographic localization of high affinity GABA, benzodiazepine, dopaminergic, adrenergic and muscarinic cholinergic receptors in the rat, monkey and human retina. Brain Res 1986; 374: 75–92
  • Eng C., Cho S., Factor S. M., Sonnenblick E. H., Kirk E. S. Myocardial micronecrosis produced by microsphere embolization. Role of α-adrenergic influence on the coronary microcirculation. Cir. Res. 1984; 54: 74–82

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