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Original Article

Thiol adducts of ethacrynic acid increase outflow facility in enucleated calf eyes

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Pages 253-258 | Received 25 Nov 1991, Accepted 02 Mar 1992, Published online: 02 Jul 2009

References

  • Epstein D. L., Freddo T. F., Bassett-Chu S., Chung M., Karageuzian L. Influence of ethacrynic acid on outflow facility in the monkey and calf eye. Invest. Ophthalmol. Vis. Sci. 1987; 28: 2067–2075
  • Ozment R. R., Nylen P., Epstein D. L. The effect of intracameral ethacrynic acid on intraocular pressure of living monkeys. Invest. Ophthalmol. Vis. Sci. 1988; 29: 84, Suppl.
  • Erickson-Lamy K., Schroeder A., Epstein D. L. Sulfhydryl agents induce reversible shape change in cultured endothelial cells. Invest. Ophthalmol. Vis. Sci. 1987; 28: 283, Suppl.)
  • Edelhauser H. F., Van Horn D. L., Miller P., Pederson H. J. Effect of thiol-oxidation of glutathione with diamide on corneal endothelial function, junctional complexes and microfilaments. J. Cell Biol. 1976; 68: 567–578
  • Koechel D. A., Cafruny E. J. Thiol adducts of ethacrynic acid: a correlation of the rate of liberation of ethacrynic acid with the onset and magnitude of the diuretic response. J. Pharmacol. Exp. Ther. 1975; 192: 179–194
  • Epstein D. L., Hashimoto J. M., Anderson P. J., Grant W. M. Effect of iodoacetamide perfusion on outflow facility and metabolism of the trabecular meshwork. Invest. Ophthalmol. Vis. Sci. 1981; 20: 625–631
  • Koechel D. A., Cafruny E. J. Synthesis and structure-activity relationship of some thiol adducts of ethacrynic acid. J. Med. Chem. 1973; 16: 1147–1152
  • Liang L. L., Erickson-Lamy K. A., de Kater A. W., Epstein D. L. Ethacrynic acid increases facility of outflow in the human eye in vitro. Arch. Ophthalmol 1992; 110: 106–109
  • Richardson T. M., Epstein D. L. Exfoliation glaucoma: a quantitative perfusion and ultrastructural study. Ophthalmology 1981; 88: 968–980
  • Lütjen-Drecoll E., Futa R., Tamm E. New ultrastructural findings in exfoliation glaucoma. Invest. Ophthalmol. Vis. Sci. 1988; 29: 274, Suppl.
  • Lütjen-Drecoll E., Futa R., Rohen J. W. Ultrahistochemical studies on tangential sections of the trabecular meshwork in normal and glaucomatous eyes. Invest. Ophthalmol. Vis. Sci. 1981; 21: 563–573
  • Schroeder A., Tingey D. P., Chen W. Y., Epstein M. P.M., Epstein D. L. Topical ethacrynic acid lowers intraocular pressure in rabbits and monkeys. Invest. Ophthalmol. Vis. Sci. 1991; 32: 870, Suppl.

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