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Current Eye Research Volume 13, 1994 - Issue 4
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Original Article

Endotoxins in cholera and pertussis toxins interfere with in vivo responses to these agents in the albino rabbit eye

T. W. Mittag Department of Ophthalmology, Mount Sinai School of Medicine, CUNY, New York, NY, 10029, USA; Department of Ophthalmology, Pharmacology, Mount Sinai School of Medicine, CUNY, New York, NY, 10029, USA
,
A. Tormay Department of Ophthalmology, Mount Sinai School of Medicine, CUNY, New York, NY, 10029, USA
&
C. Severin Department of Ophthalmology, Mount Sinai School of Medicine, CUNY, New York, NY, 10029, USA
Pages 311-313 | Received 09 Nov 1992, Accepted 04 Feb 1994, Published online: 02 Jul 2009

References

  • Cassel D., Pfeuffer T. Mechanism of choleratoxin action: Covalent modification of the guanine nucleotide binding protein of the adenylyl cyclase system. Proc. Nat. Acad. Sci. USA 1978; 75: 2669–2673
  • Ui M. Islet activating protein, pertussis toxin: a probe for functions of the inhibitory guanine nucleotide regulatory component of adenylate cyclase. Trends Pharmacol. Sci. 1984; 5: 277–279
  • Gregory D., Sears M., Bausher L., Mishima H., Meade A. Intraocular pressure and aqueous flow are decreased by cholera toxin. Invest. Ophthalmol. Vis. Sci. 1981; 20: 371–381
  • Bartels S. P., Roth H. O., Neufeld A. H. Effects of intravitreal cholera toxin on adenosine-3,5-monophosphate, intraocular pressure, and outflow facility in rabbits. Invest. Ophthalmol. Vis. Sci. 1981; 20: 410–414
  • Mishima H., Sears M., Bausher L., Gregory D. Ultracytochemistry of cholera toxin binding sites in ciliary processes. Cell Tiss. Res. 1982; 223: 241–253
  • Sears M. L. Regulation of aqueous flow by the adenylyl cyclase receptor complex in the ciliary epithelium. Am. J. Ophthalmol. 1985; 100: 194–198
  • Caprioli J., Sears M., Bausher L., Mead A. Forskolin lowers intraocular pressure by reducing aqueous flow. Invest. Ophthalmol. Vis. Sci. 1984; 25: 268–277
  • Mittag T. W., Tormay A., Severin C., Lind G., Yoshimura N., Podos S. M. Role of G-Proteins in ciliary process adenylyl cyclase responses of the albino rabbit eye. Curr. Eye Res. 1994; 13: 243–250

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