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Journal of Asthma Volume 47, 2010 - Issue 10
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Asthma Treatment

A Phase I Randomized, Placebo-Controlled, Dose-Exploration Study of Single-Dose Inhaled Montelukast in Patients with Chronic Asthma

George Philip Merck Research Laboratories, North Wales, PA, USA.Correspondence[email protected]
, M.D.,
Andrew Pedinoff The Princeton Center for Clinical Research, Princeton, NJ, USA.
, M.D.,
Kristel Vandormael Merck Research Laboratories, Brussels, Belgium.
, M.Sc.,
Yevgen Tymofyeyev Merck Research Laboratories, Rahway, NJ, USA.
, Ph.D.,
Steven S. Smugar Merck Research Laboratories, North Wales, PA, USA.
, M.D.,
Theodore F. Reiss Merck Research Laboratories, North Wales, PA, USA.
, M.D. &
Phillip E. Korenblat Washington University School of Medicine, St. Louis, MO, USA.
, M.D. show all
Pages 1078-1084 | Published online: 03 Nov 2010

Reference List

  • Storms W. Update on montelukast and its role in the treatment of asthma, allergic rhinitis and exercise-induced bronchoconstriction. Expert Opin Pharmacother 2007; 8:2173–2187.
  • de Benedictis FM, Vaccher S, de Benedictis D. Montelukast sodium for exercise-induced asthma. Drugs Today (Barc) 2008; 44:845–855.
  • Nayak A, Langdon RB. Montelukast in the treatment of allergic rhinitis: An evidence-based review. Drugs 2007; 67:887–901.
  • Joos S, Miksch A, Szecsenyi J, Wieseler B, Grouven U, Kaiser T, Montelukast as add-on therapy to inhaled corticosteroids in the treatment of mild to moderate asthma: A systematic review. Thorax 2008; 63:453–462.
  • Reiss TF, Sorkness CA, Stricker W, Botto A, Busse WW, Kundu S, Effects of montelukast (MK-0476); a potent cysteinyl leukotriene receptor antagonist, on bronchodilation in asthmatic subjects treated with and without inhaled corticosteroids. Thorax 1997; 52:45–48.
  • Reiss TF, Altman LC, Chervinsky P, Bewtra A, Stricker WE, Noonan GP, Effects of montelukast (MK-0476), a new potent cysteinyl leukotriene (LTD4) receptor antagonist, in patients with chronic asthma. J Allergy Clin Immunol 1996; 98:528–534.
  • Altman LC, Munk Z, Seltzer J, Noonan N, Shingo S, Zhang J, A placebo-controlled, dose-ranging study of montelukast, a cysteinyl leukotriene-receptor antagonist. Montelukast Asthma Study Group. J Allergy Clin Immunol 1998; 102:50–56.
  • Dockhorn RJ, Baumgartner RA, Leff JA, Noonan M, Vandormael K, Stricker W, Comparison of the effects of intravenous and oral montelukast on airway function: A double blind, placebo controlled, three period, crossover study in asthmatic patients. Thorax 2000; 55:260–265.
  • Standardization of Spirometry. 1994 Update. American thoracic society. Am J Respir Crit Care Med 1995; 152:1107–1136.
  • PROAIR® HFA (albuterol sulfate) inhalation aerosol package insert. Teva Specialty Pharmaceuticals LLC, Horsham, PA, 2008.
  • Noonan MJ, Chervinsky P, Brandon M, Zhang J, Kundu S, McBurney J, Montelukast, a potent leukotriene receptor antagonist, causes dose-related improvements in chronic asthma. Montelukast Asthma Study Group. Eur Respir J 1998; 11:1232–1239.

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