Salbutamol Sulfate Absorption Across Calu-3 Bronchial Epithelia Cell Monolayer is Inhibited in the Presence of Common Anionic NSAIDs

References

• Lin SY, Chen KS, Lin YY. pH of preparations affecting the on-off drug penetration behavior through the thermo-responsive liquid crystal-embedded membrane. J Controlled Release 1998; 55(1):13–20.
   PubMed Web of Science ®Google Scholar
• Abdul F, Gurpreet S, Ishar MPS. In vitro passive and iontophoretically assisted transport of salbutamol sulphate through hairless mice skin. Int J Pharmaceut Science Nanotechnol 2010; 3(1):811–818.
   Google Scholar
• Suresh KB, Sundeep SS. Aspirin and asthma. Chest 2000; 118:1470–1476.
   PubMed Web of Science ®Google Scholar
• Kasper L, Sladek K, Duplaga M, Bochenek G, Liebhart J, Gladysz U, Malolepszy J, Szczeklik A. Prevalence of asthma with aspirin hypersensitivity in the adult population of Poland. Allergy 2003; 58(10):1064–1066.
   PubMed Web of Science ®Google Scholar
• Jenkins C, Costello J, Hodge L. Systematic review of prevalence of aspirin induced asthma and its implications for clinical practice. Br Med J 2004; 328(7437):434–437.
   PubMed Web of Science ®Google Scholar
• http://www.ncbi.nlm.nih.gov/books/NBK7238/. Accessed January 2013.
   Google Scholar
• Berges-Gimeno MP, Simon RA, Stevenson DD. The natural history and clinical characteristics of aspirin-exacerbated respiratory disease. Ann Allergy Asthma Immunol 2002; 89(5):474–478.
   PubMed Web of Science ®Google Scholar
• Ferreri NR, Howland WC, Stevenson DD. Spielberg HLRelease of leukoterins, prostaglandins, and histamine into nasal secretions of aspirin sensitive asthmatics during reaction to aspirin. Am Rev Respir Dis 1988; 137:847.
   PubMed Web of Science ®Google Scholar
• Settipane RA, Stevenson DD. Cross sensitivity with acetaminophen in aspirin-sensitive subjects with asthma. J Allergy Clin Immunol 1989; 84(1):26–33.
   PubMed Web of Science ®Google Scholar
• Stevenson DD, Simon RA, Zuraw BL. Sensitivity to aspirin and non- steroidal anti-inflammatory drugs. In: Adkinson N and Yunginger JW, eds. Middleton– Allergy Principles and Practice. 6th ed. Philadelphia: Mosby, 2003:1695–1710.
   Google Scholar
• Hamad AM, Sutcliffe AM, Knox AJ. Aspirin-induced asthma: Clinical aspects, pathogenesis and management. Drugs 2004; 64(21):2417–2432.
   PubMed Web of Science ®Google Scholar
• Bosquillon C. Drug transporters in the lung—Do they play a role in the biopharmaceutics of inhaled drugs? J Pharm Sci 2010; 99(5):2240–2255. doi: 10.1002/jps.21995.
   PubMed Web of Science ®Google Scholar
• Zolk O, Fromm MF. Transporter-mediated drug uptake and efflux: Important determinants of adverse drug reactions. Clin Pharmacol Ther 2011; 89(6):798–805.
   PubMed Web of Science ®Google Scholar
• Koepsell H, Lips K, Volk C. Polyspecific organic cation transporters: Structure, function, physiological roles, and biopharmaceutical implications. Pharm Res 2007; 24(7):1227–1251.
   PubMed Web of Science ®Google Scholar
• Khamdang S, Takeda M, Noshiro R, Narikawa S, Enomoto A, Anzai N, Piyachaturawat P, Endou H. Interactions of human organic anion transporters and human organic cation transporters with nonsteroidal anti-inflammatory drugs. J Pharmacol Exp Ther 2002; 303(2):534–539.
   Google Scholar
• Wang J, Hughes TP, Kok CH, Saunders VA, Frede A, Groot-Obbink K, Osborn M, Somogyi AA, D’Andrea RJ, White DL. Contrasting effects of diclofenac and ibuprofen on active imatinib uptake into leukaemic cells. Br J Cancer 2012; 106 (11):1772–1778.
   Google Scholar
• Ehrhardt C, Kneuer C, Bies C, Lehr CM, Kim KJ, Bakowsky U. Salbutamol is actively absorbed across human bronchial epithelial cell layers. Pulm Pharmacol Ther 2005; 18(3):165–170.
   PubMed Web of Science ®Google Scholar
• Horvath G, Mendes ES, Schmid N, Schmid A, Conner GE, Salathe M, Wanner A. The effect of corticosteroids on the disposal of long-acting beta2-agonists by airway smooth muscle cells. 2007; 120(5):1103–1109.
   Google Scholar
• Mukherjee M, Pritchard DI, Bosquillon C. Evaluation of air-interfaced Calu-3 cell layers for investigation of inhaled drug interactions with organic cation transporters in vitro. Int J Pharm 2012; 426(1-2):7 –14.
   Google Scholar
• Shen BQ, Finkbeiner WE, Wine JJ, Mrsny RJ, Widdicombe JH. Calu-3: A human airway epithelial cell line that shows cAMP-dependent Cl- secretion. Am J Physiol 1994; 266(5 10–5):L493–L501.
   PubMedGoogle Scholar
• Haghi M, Young PM, Traini D, Jaiswal R, Gong J, Bebawy M. Time- and passage-dependent characteristics of a Calu-3 respiratory epithelial cell model. Drug Dev Ind Pharm 2010; 36(10):1207–1214.
   Google Scholar
• Hamilton KO, Topp E, Makagiansar I, Siahaan T, Yazdanian M, Audus KL. Multidrug resistance-associated protein-1 functional activity in Calu-3 cells. J Pharmacol Exp Ther 2001; 298(3):1199–1205.
   PubMed Web of Science ®Google Scholar
• Li C, Schuetz JD, Naren AP. Tobacco carcinogen NNK transporter MRP2 regulates CFTR function in lung epithelia: Implications for lung cancer. Cancer Letter 2010; 292(2):246–253. doi: 10.1016/j.canlet.2009.12.009.
   PubMed Web of Science ®Google Scholar
• Paturi DK, Kwatra D, Ananthula HK, Pal D, Mitra AK. Identification and functional characterization of breast cancer resistance protein in human bronchial epithelial cells (Calu-3). Int J Pharm 2010; 384(1–2):32–38.
   PubMed Web of Science ®Google Scholar
• Sachs LA, Finkbeiner WE, Widdicombe JH. Effects of media on differentiation of cultured human tracheal epithelium. Vitro Cell Dev Biol Anim 2003; 39(1–2):56–62.
   PubMed Web of Science ®Google Scholar
• Ehrhardt C, Kneuer C, Fiegel J, Hanes J, Schaefer UF, Kim KJ, Lehr CM. Influence of apical fluid volume on the development of functional inter-cellular junctions in the human epithelial cell line. Cell and Tissue Research 2002; 308(3):391–400.
   Google Scholar
• Stentebjerg-Andersen A, Notlevsen IV, Brodin B, Nielsen CU. Calu-3 cells grown under AIC and LCC conditions: Implications for dipeptide uptake and transepithelial transport of substances. Eur J Pharm Biopharm 2011; 78(1):19–26.
   PubMed Web of Science ®Google Scholar
• Grainger CI, Greenwell LL, Lockley DJ, Martin GP, Forbes B. Culture of Calu-3 cells at the air interface provides a representative model of the airway epithelial barrier. Pharm Res 2006; 23(7):1482–1490.
   PubMed Web of Science ®Google Scholar
• Bur M, Huwer H, Muys L, Lehr CM. Drug transport across pulmonary epithelial cell monolayers: Effects of particle size, apical liquid volume, and deposition technique. J Aerosol Med Pulm Drug Deliv 2010; 23(3):119–127.
   PubMed Web of Science ®Google Scholar
• Horvath G, Schmid N, Fragoso MA, Schmid A, Conner GE, Salathe M, Wanner A. Epithelial organic cation transporters ensure pH-dependent drug absorption in the airway. Am J Respir Cell Mol Biol 2007; 36(1):53–60.
   Google Scholar
• Endter S, Francombe D, Ehrhardt C, Gumbleton M. RT-PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell models. J Pharm Pharmacol 2009; 61(5):583–591.
   PubMed Web of Science ®Google Scholar
• Salomon JJ, Endter S, Tachon G, Falson F, Buckley ST, Ehrhardt C. Transport of the fluorescent organic cation 4-(4-(dimethylamino)styryl)-N-methylpyridinium iodide (ASP +) in human respiratory epithelial cells. Eur J Pharm Biopharm 2012; 81(2):351–359.
   PubMed Web of Science ®Google Scholar
• Barbato F, La Rotonda MI, Quaglia F. Interactions of nonsteroidal antiinflammatory drugs with phospholipids: Comparison between octanol/buffer partition coefficients and chromatographic indexes on immobilized artificial membranes. J Pharm Sci 1997; 86(2):225–229.
   PubMed Web of Science ®Google Scholar
• Hvidberg E, Lausen HH, Jansen JA. Indomethacin: Plasma concentrations and protein binding in man. Eur J Clin Pharmacol 1972; 4(2):119–124.
   PubMed Web of Science ®Google Scholar
• Wood DM, Monaghan J, Streete P, Jones AL, Dargan PI. Fatality after deliberate ingestion of sustained-release ibuprofen: A case report. Crit Care 2006; 10(2):R44.
   PubMed Web of Science ®Google Scholar
• Baselt R. Disposition of Toxic Drugs and Chemicals in Man. 8th ed. Foster City: Biomedical Publications, 2008:22–25.
   Google Scholar
• Bramlage P, Goldis A. Bioequivalence study of three ibuprofen formulations after single dose administration in healthy volunteers. BMC Pharmacol 2008; 8:18.
   Google Scholar