References
- Peat JK, Woolcock AJ, Cullen K. Rate of decline of lung function in subjects with asthma. Eur J Respir Dis 1987;70:171–179
- Lange P, Parner J, Vestbo J, Schnohr P, Jensen G. A 15-year follow-up study of ventilatory function in adults with asthma. N Engl J Med 1998;339:1194–1200
- Dijkstra A, Vonk JM, Jongepier H, Koppelman GH, Schouten JP, ten Hacken NH, Timens W, Postma DS. Lung function decline in asthma: association with inhaled corticosteroids, smoking and sex. Thorax 2006;61:105–110
- Bai TR, Vonk JM, Postma DS, Boezen HM. Severe exacerbations predict excess lung function decline in asthma. Eur Respir J 2007;30:452–456
- O’Byrne PM, Pedersen S, Lamm CJ, Tan WC, Busse WW. Severe exacerbations and decline in lung function in asthma. Am J Respir Crit Care Med 2009;179:19–24
- Marcon A, Corsico A, Cazzoletti L, Bugiani M, Accordini S, Almar E, Cerveri I, et al. Body mass index, weight gain, and other determinants of lung function decline in adult asthma. J Allergy Clin Immunol 2009;123:1069–1074, 74 e1–4
- Holgate ST, Polosa R. The mechanisms, diagnosis, and management of severe asthma in adults. Lancet 2006;368:780–793
- Moore WC, Meyers DA, Wenzel SE, Teague WG, Li H, Li X, D’Agostino R Jr, et al. Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med 2010;181:315–323
- Fitzpatrick AM, Teague WG, Meyers DA, Peters SP, Li X, Li H, Wenzel SE, et al. Heterogeneity of severe asthma in childhood: confirmation by cluster analysis of children in the National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program. J Allergy Clin Immunol 2010;127:382–389, e1–13
- Wardlaw AJ, Silverman M, Siva R, Pavord ID, Green R. Multi-dimensional phenotyping: towards a new taxonomy for airway disease. Clin Exp Allergy 2005;35:1254–1262
- Wenzel SE. Asthma: defining of the persistent adult phenotypes. Lancet 2006;368:804–813
- Heaney LG, Robinson DS. Severe asthma treatment: need for characterising patients. Lancet 2005;365:974–976
- Weatherall M, Travers J, Shirtcliffe PM, Marsh SE, Williams MV, Nowitz MR, Aldington S, Beasley R. Distinct clinical phenotypes of airways disease defined by cluster analysis. Eur Respir J 2009;34:812–818
- Silverstein MD, Reed CE, O’Connell EJ, Melton LJ III, O’Fallon WM, Yunginger JW. Long-term survival of a cohort of community residents with asthma. N Engl J Med 1994;331:1537–1541
- Lange P, Ulrik CS, Vestbo J. Mortality in adults with self-reported asthma. Copenhagen City Heart Study Group. Lancet 1996;347:1285–1289
- Ulrik CS. Outcome of asthma: longitudinal changes in lung function. Eur Respir J 1999;13:904–918
- Ulrik CS, Lange P. Decline of lung function in adults with bronchial asthma. Am J Respir Crit Care Med 1994;150:629–634
- James AL, Palmer LJ, Kicic E, Maxwell PS, Lagan SE, Ryan GF, Musk AW. Decline in lung function in the Busselton Health Study: the effects of asthma and cigarette smoking. Am J Respir Crit Care Med 2005;171:109–114
- de Marco R, Marcon A, Jarvis D, Accordini S, Bugiani M, Cazzoletti L, Cerveri I, et al. Inhaled steroids are associated with reduced lung function decline in subjects with asthma with elevated total IgE. J Allergy Clin Immunol 2007;119:611–617
- Miranda C, Busacker A, Balzar S, Trudeau J, Wenzel SE. Distinguishing severe asthma phenotypes: role of age at onset and eosinophilic inflammation. J Allergy Clin Immunol 2004;113:101–108
- Matsunaga K, Akamatsu K, Miyatake A, Ichinose M. Natural history and risk factors of obstructive changes over a 10-year period in severe asthma. Respir Med 2013;107:355–360
- Hudon C, Turcotte H, Laviolette M, Carrier G, Boulet LP. Characteristics of bronchial asthma with incomplete reversibility of airflow obstruction. Ann Allergy Asthma Immunol 1997;78:195–202
- Ward JH Jr. Hierarchical grouping to optimize an objective function. J Am Stat Assoc 1963;48:236–244
- Mark Hall EF, Holmes G, Pfahringer B, Reutemann P, Witten IH. The WEKA data mining software: an update. SIGKDD Explorations 2009;11:10--18
- Bousquet J. Global initiative for asthma (GINA) and its objectives. Clin Exp Allergy 2000;30:2–5
- Bateman ED, Hurd SS, Barnes PJ, Bousquet J, Drazen JM, FitzGerald M, Gibson P, et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008;31:143–178
- Selroos O, Pietinalho A, Lofroos AB, Riska H. Effect of early vs late intervention with inhaled corticosteroids in asthma. Chest 1995;108:1228–1234
- Koyanagi K, Koya T, Sasagawa M, Hasegawa T, Suzuki E, Arakawa M, Gejyo F. An analysis of factors that exacerbate asthma, based on a Japanese questionnaire. Allergol Int 2009;58:519–527