Effect of Radioprotective Aminothiols on the Induction and Repair of Single-Strand Breaks in the DNA of Irradiated Mammalian Cells

References

• Alexander P., Dean C. J., Lehmann A. R., Ormerod M. G., Feldschreiber P., Seranni R. W. The repair of DNA and the mode of action of sensitizers and protectors in biological systems of different complexity. Radiation protection and sensitization, H. Moroson, M. Quintiliani. Taylor & Francis, London 1970; 15
   Google Scholar
• Antoku S. Chemical protection against radiation-induced DNA single-strand breaks in cultured mammalian cells. Radiat. Res. 1976; 65: 130
   Google Scholar
• Doherty D. G., Burnett W. T., Jr., Shapira R. Chemical protection against ionizing radiation. II. Mercaptoakylamines and related compounds with protective activity. Radiat. Res. 1957; 7: 13
   PubMed Web of Science ®Google Scholar
• Fuks Z., Smith K. C. Effect of quinacrine on X-ray sensitivity and the repair of damaged DNA in Escherichia coli K-12. Radiat. Res. 1971; 48: 63
   PubMed Web of Science ®Google Scholar
• Ginsberg D. M., Webster H. K. Chemical protection against single-strand breaks in DNA of gamma-irradiated E. coli. Radiat. Res. 1969; 39: 421
   Google Scholar
• Jellum E. The role of cysteamine-nucleic-acid interactions in protection against X-ray-induced damage of DNA. Int. J. Radiat. Biol. 1966; 10: 577
   Web of Science ®Google Scholar
• Kollmann G., Shapiro B., Martin D. Mechanism of the protective action of GED against radiation damage to DNA. Radiat. Res. 1967; 31: 721
   Google Scholar
• Leon S. A., Kollmann G., Shapiro B. In vitro protection against radiation damage to template activity in DNA synthesis. Int. J. Radiat. Biol. 1971; 20: 337
   Web of Science ®Google Scholar
• Littbrand B. Oxygen-dependent radiosensitivity variation of mammalian cells. Thesis, Karolinska Institutet, Stockholm 1971
   Google Scholar
• Littbrand B., Révész L. The effect of oxygen on cellular survival and recovery after radiation. Brit. J. Radiol. 1969; 42: 914
   PubMed Web of Science ®Google Scholar
• Lohman P. H. M. Induction and rejoining of breaks in the deoxyribonucleic acid of human cells irradiated at various phases of the cell cycle. Mutation Res. 1968; 6: 449
   PubMedGoogle Scholar
• Lohman P. H. M., Vos O., van Sluis C. A., Cohen J. A. Chemical protection against breaks induced in DNA of human and bacterial cells by X-irradiation. Biochim. biophys. Acta 1970; 224: 339
   Google Scholar
• Loman H., Voogd S., Blok J. Indirect radioprotection by sulphydryl compounds. A model chemical system. Radiat. Res. 1970; 42: 437
   PubMedGoogle Scholar
• McGrath R. A., Williams R. W. Reconstruction in vivo of irradiated Escherichia coli deoxyribonucleic acid; the rejoining of broken pieces. Nature 1966; 212: 534
   PubMed Web of Science ®Google Scholar
• Milvy P. Dose-dependence of the transfer of radiation-induced free radicals from DNA to cysteamine. Radiat. Res. 1971; 47: 83
   PubMedGoogle Scholar
• Modig H. G., Edgren M., Révész L. Dual effect of oxygen on the induction and repair of single-strand breaks in the DNA of X-irradiated mammalian cells. Int. J. Radiat. Biol. 1974; 26: 341
   Web of Science ®Google Scholar
• Ormerod M. G., Stevens U. The rejoining of X-ray-induced strand breaks in the DNA of a murine lymphoma cell (L5178Y). Biochim. biophys. Acta 1971; 232: 72
   PubMed Web of Science ®Google Scholar
• Révész L., Modig H. G., Konstantinova M. M. Release of endogenous glutathione by exposure of cell cultures to Thiola. Proc. 2nd Internat. Symp. on Thiola. San ten Pharmaceutical Co., OsakaJapan 1974; 12
   Google Scholar
• Sawada S., Okada S. Cysteamine, cystamine and single-strand breaks of DNA in cultured mammalian cells. Radiat. Res. 1970; 44: 116
   PubMed Web of Science ®Google Scholar
• Sugahara T., Tanaka Y., Nagata H., Kano E., Tanaka T. Radiation protection by 2-mercaptopropionylglycine. Proc. Internat. Symp. on Thiola. Santen Pharmaceutical Co., OsakaJapan 1970; 267
   Google Scholar
• Takagi Y., Shikita M., Terasima T., Akaboshi S. Specificity of radioprotective and cytotoxic effects of cysteamine in HeLa S3 cells. Generation of peroxide as the mechanism of paradoxical toxicity. Radiat. Res. 1974; 60: 292
   PubMed Web of Science ®Google Scholar
• Vos O., Eudke L., Vergroesen A. J. Protection of tissue-culture cells against ionizing radiation. I. The effect of biological amines, disulphide compounds and thiols. Int. J. Radiat. Biol. 1962; 5: 543
   Web of Science ®Google Scholar
• Vos O., Grant G. A., Budke L. Protection against X-irradiation employing cysteamine derivatives in tissue culture and in mice. Int. J. Radiat. Biol. 1970; 18: 111
   Google Scholar