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Original Article

Distribution of DNA Cleavages Induced by Bleomycin and Neocarzinostatin in A Defined Sequence of Rat Glioma Cells

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Pages 353-357 | Received 08 Jul 1991, Accepted 30 Nov 1991, Published online: 08 Jul 2009

References

  • Umezawa H, Maeda H, Takeuchi T, Okami Y. New antibiotics, bleomycin A and B. J Antibiot 1966; 19: 200–9
  • Ishida N, Mizake K, Kumagai K, Rikimaru M. Neocarzinostatin, an antitumor antibiotic of high molecular weight: isolation, physiochemical properties and biological activity. J Antibiot 1965; 18: 68–76
  • Goldberg I H, Hatayama T, Kappen L S, Napier M A, Povirk L F. Protein antibiotics as DNA damaging agents. Molecular action on targets for cancer chemotherapeutic agents, A C Sartorelli, J R Bertino, S S Lajo. Academic Press, New York 1981; 163–91
  • Berlin V, Haseltine W A. Reduction of adriamycin to a semiquinone-free radical by NADPH cytochrome P-450 produces DNA cleavage in a reaction medicated by molecular oxygen. J Biol Chem 1981; 256: 4747–56
  • D'Andrea A D, Haseltine W A. Sequence specific cleavage of DNA by the antitumor antibiotics neocarzinostatin and bleomycin. Proc Natl Acad Sci USA 1978; 75: 3608–12
  • D'Andrea A D, Haseltine W A. Modification of DNA by aflatoxin B, creates alkali-labile lesions in DNA at positions of guanine and adenine. Proc Natl Acad Sci USA 1978; 75: 4120–4
  • Grunberg S M, Haseltine W A. Use of indicator sequence of human DNA to study DNA damage by methylbis(2-chloroethyl)amine. Proc Natl Acad Sci USA 1980; 77: 6546–50
  • Haseltine W A, Lindan C P, D'Andrea A D, Johnsrud L. The use of DNA fragments of defined sequence for the study of DNA damage and repair. Methods Enzymol 1980; 65: 235–48
  • Haseltine W A, Lo K M, D'Andrea A D. Preferred Sites of strand scission in DNA modified by anti-diol exposure of benzo‘a’pyrene. Science 1980; 209: 929–31
  • Lippke J A, Gordon L K, Brash D E, Haseltine W A. Distribution of UV light-induced damage in a defined sequence of human DNA: detection of alkaline-sensitive lesion at pyrim-idine nucleoside-cytidine sequences. Proc Natl Acad Sci USA 1981; 78: 3383–92
  • Royer-Pokora B, Gordon L K, Haseltine W A. Use of exonucle-ase III to determine the site of stable lesions in defined sequence of DNA: the cyclobutane pyrimidine dimer and cis- and trans-dichlorodiammine platinum II examples. Nucl Acids Res 1981; 9: 4595–609
  • Benda P, Lightbodty J, Sato G, Levine L, Sweet W. Differentiated rat glial cell strain in tissue culture. Science 1968; 161: 370–1
  • Smith H O. Recovery of DNA from gels. Methods Enzymol 1980; 65: 371–80
  • Maniatis T, Fritsch E F, Sambrook J. Molecular cloning. Cold Spring Harbor laboratory, New York 1982
  • Maxam A M, Gilbert W. Sequencing end-labeled DNA with base-specific cleavages. Methods Enzymol 1980; 65: 499–560
  • Takeshita M, Grollman A P, Ohtsubo E, Ohtsubo T. Interaction of bleomycin with DNA. Proc Natl Acad Sci USA 1978; 75: 5983–7
  • Takeshita M, Kappen L S, Grollman A P, Eisenberg M, Goldberg I H. Strand scission of deoxyribonucleic acid by neocarzinostatin, auromomycin, and bleomycin: studies on base release and nucleotide sequence specificity. Biochemistry 1981; 20: 7599–606
  • Hatayama T, Goldberg I H, Takeshita M, Grollman A P. Nucleotide specificity in DNA scission by neocarzinostatin. Proc Natl Acad Sci USA 1978; 75: 3603–7
  • Manuelidis L, Wu J C. Homology between human and simian repeated DNA. Nature 1978; 276: 92–4
  • Wu J C, Manuelidis L. Sequence definition and organization of a human repeated DNA. J Mol Biol 1980; 142: 363–86
  • Weiss R B, Mineura K, Henderson E E, Duker N J, de Riel J K. Enzymic detection of uracil in a cloned and sequenced deoxyribonucleic acid segment. Biochemistry 1983; 22: 4501–7
  • Fushimi S, Mineura K, Itoh Y, Kowada M. In vitro damage of isolated DNA from two brain tumor cell lines induced by a water-soluble antitumor nitrosourea. Acta Neurol Scand 1988; 77: 445–9
  • Mineura K, Fushimi S, Itoh Y, Kowada M. DNA lability induced by nimustine and ramustine in rat glioma cells. J Neurol Neurosurg Psychiatry 1988; 51: 1391–4
  • Pech M, Igo-Kemenes T, Zachau H G. Nucleotide sequence of a highly repetitive component of rat DNA. Nucl Acids Res 1979; 7: 417–32
  • Burger R M, Berkowitz A R, Peisach J, Horwitz S B. Origin of malondialdehyde from DNA degraded by Fe(II)bleomycin. J Biol Chem 1980; 255: 11832–8
  • Giloni L, Takeshita M, Johnson F, Iden C, Grollman A P. Bleomycin-induced strand-scission of DNA. Mechanism of deoxyribose cleavage. J Biol Chem 1981; 256: 8608–15
  • Hashimoto Y, Iijima H, Nozaki Y, Shudo K. Functional analogues of bleomycin: DNA cleavage by bleomycin and hemin-intercalators. Biochemistry 1986; 25: 5103–10
  • Kappen L S, Goldberg I H. Deoxyribonucleic acid damage by neocarzinostatin chromophore: strand breaks generated by selective oxidation of C-5′ of deoxyribose. Biochemistry 1983; 22: 4872–8
  • Murray V, Martin R F. The sequence specificity of bleomycin-induced DNA damage in intact cells. J Biol Chem 1985; 260: 10389–91
  • Kappen L S, Ellenberger T E, Goldberg I H. Mechanism and base specificity of DNA breakage in intact cells by neocarzinostatin. Biochemistry 1987; 26: 384–90

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