References
- Umezawa H, Maeda H, Takeuchi T, Okami Y. New antibiotics, bleomycin A and B. J Antibiot 1966; 19: 200–9
- Ishida N, Mizake K, Kumagai K, Rikimaru M. Neocarzinostatin, an antitumor antibiotic of high molecular weight: isolation, physiochemical properties and biological activity. J Antibiot 1965; 18: 68–76
- Goldberg I H, Hatayama T, Kappen L S, Napier M A, Povirk L F. Protein antibiotics as DNA damaging agents. Molecular action on targets for cancer chemotherapeutic agents, A C Sartorelli, J R Bertino, S S Lajo. Academic Press, New York 1981; 163–91
- Berlin V, Haseltine W A. Reduction of adriamycin to a semiquinone-free radical by NADPH cytochrome P-450 produces DNA cleavage in a reaction medicated by molecular oxygen. J Biol Chem 1981; 256: 4747–56
- D'Andrea A D, Haseltine W A. Sequence specific cleavage of DNA by the antitumor antibiotics neocarzinostatin and bleomycin. Proc Natl Acad Sci USA 1978; 75: 3608–12
- D'Andrea A D, Haseltine W A. Modification of DNA by aflatoxin B, creates alkali-labile lesions in DNA at positions of guanine and adenine. Proc Natl Acad Sci USA 1978; 75: 4120–4
- Grunberg S M, Haseltine W A. Use of indicator sequence of human DNA to study DNA damage by methylbis(2-chloroethyl)amine. Proc Natl Acad Sci USA 1980; 77: 6546–50
- Haseltine W A, Lindan C P, D'Andrea A D, Johnsrud L. The use of DNA fragments of defined sequence for the study of DNA damage and repair. Methods Enzymol 1980; 65: 235–48
- Haseltine W A, Lo K M, D'Andrea A D. Preferred Sites of strand scission in DNA modified by anti-diol exposure of benzo‘a’pyrene. Science 1980; 209: 929–31
- Lippke J A, Gordon L K, Brash D E, Haseltine W A. Distribution of UV light-induced damage in a defined sequence of human DNA: detection of alkaline-sensitive lesion at pyrim-idine nucleoside-cytidine sequences. Proc Natl Acad Sci USA 1981; 78: 3383–92
- Royer-Pokora B, Gordon L K, Haseltine W A. Use of exonucle-ase III to determine the site of stable lesions in defined sequence of DNA: the cyclobutane pyrimidine dimer and cis- and trans-dichlorodiammine platinum II examples. Nucl Acids Res 1981; 9: 4595–609
- Benda P, Lightbodty J, Sato G, Levine L, Sweet W. Differentiated rat glial cell strain in tissue culture. Science 1968; 161: 370–1
- Smith H O. Recovery of DNA from gels. Methods Enzymol 1980; 65: 371–80
- Maniatis T, Fritsch E F, Sambrook J. Molecular cloning. Cold Spring Harbor laboratory, New York 1982
- Maxam A M, Gilbert W. Sequencing end-labeled DNA with base-specific cleavages. Methods Enzymol 1980; 65: 499–560
- Takeshita M, Grollman A P, Ohtsubo E, Ohtsubo T. Interaction of bleomycin with DNA. Proc Natl Acad Sci USA 1978; 75: 5983–7
- Takeshita M, Kappen L S, Grollman A P, Eisenberg M, Goldberg I H. Strand scission of deoxyribonucleic acid by neocarzinostatin, auromomycin, and bleomycin: studies on base release and nucleotide sequence specificity. Biochemistry 1981; 20: 7599–606
- Hatayama T, Goldberg I H, Takeshita M, Grollman A P. Nucleotide specificity in DNA scission by neocarzinostatin. Proc Natl Acad Sci USA 1978; 75: 3603–7
- Manuelidis L, Wu J C. Homology between human and simian repeated DNA. Nature 1978; 276: 92–4
- Wu J C, Manuelidis L. Sequence definition and organization of a human repeated DNA. J Mol Biol 1980; 142: 363–86
- Weiss R B, Mineura K, Henderson E E, Duker N J, de Riel J K. Enzymic detection of uracil in a cloned and sequenced deoxyribonucleic acid segment. Biochemistry 1983; 22: 4501–7
- Fushimi S, Mineura K, Itoh Y, Kowada M. In vitro damage of isolated DNA from two brain tumor cell lines induced by a water-soluble antitumor nitrosourea. Acta Neurol Scand 1988; 77: 445–9
- Mineura K, Fushimi S, Itoh Y, Kowada M. DNA lability induced by nimustine and ramustine in rat glioma cells. J Neurol Neurosurg Psychiatry 1988; 51: 1391–4
- Pech M, Igo-Kemenes T, Zachau H G. Nucleotide sequence of a highly repetitive component of rat DNA. Nucl Acids Res 1979; 7: 417–32
- Burger R M, Berkowitz A R, Peisach J, Horwitz S B. Origin of malondialdehyde from DNA degraded by Fe(II)bleomycin. J Biol Chem 1980; 255: 11832–8
- Giloni L, Takeshita M, Johnson F, Iden C, Grollman A P. Bleomycin-induced strand-scission of DNA. Mechanism of deoxyribose cleavage. J Biol Chem 1981; 256: 8608–15
- Hashimoto Y, Iijima H, Nozaki Y, Shudo K. Functional analogues of bleomycin: DNA cleavage by bleomycin and hemin-intercalators. Biochemistry 1986; 25: 5103–10
- Kappen L S, Goldberg I H. Deoxyribonucleic acid damage by neocarzinostatin chromophore: strand breaks generated by selective oxidation of C-5′ of deoxyribose. Biochemistry 1983; 22: 4872–8
- Murray V, Martin R F. The sequence specificity of bleomycin-induced DNA damage in intact cells. J Biol Chem 1985; 260: 10389–91
- Kappen L S, Ellenberger T E, Goldberg I H. Mechanism and base specificity of DNA breakage in intact cells by neocarzinostatin. Biochemistry 1987; 26: 384–90