184
Views
6
CrossRef citations to date
0
Altmetric
Original Article

Interstitial Fluid Pressure in Human Melanoma Xenografts Relationship to fractional tumor water content, tumor size, and tumor volume-doubling time

&
Pages 361-365 | Received 25 Sep 1994, Accepted 18 Nov 1994, Published online: 08 Jul 2009

References

  • Young J S, Lumsden C E, Stalker A L. The significance of the ‘otissue pressure’ of normal testicular and of neoplastic (Brown-Pearce carcinoma) tissue in rabbit. J Pathol Bacteriol 1950; 62: 313–33
  • Wiig H, Tveit E, Hultborn R, Reed R K, Weiss L. Interstitial fluid pressure in DMBA-induced rat mammary tumours. Scand J Clin Lab Invest 1982; 42: 159–64
  • Paskins-Hurlburt A J, Hollenberg N K, Abrams H L. Tumor perfusion in relation to the rapid growth phase and necrosis: studies on the Walker carcinoma in the rat testicle. Microvasc Res 1982; 24: 15–24
  • Hori K, Suzuki M, Abe I, Saito S. Increased tumor tissue pressure in association with the growth of rat tumors. Gann 1986; 77: 65–73
  • Boucher Y, Baxter L T, Jain R K. Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: implications for therapy. Cancer Res 1990; 50: 4478–84
  • Lee I, Boucher Y, Jain R K. Nicotinamide can lower tumor interstitial fluid pressure: mechanistic and therapeutic implications. Cancer Res 1992; 52: 3237–40
  • Boucher Y, Jain R K. Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: implications for vascular collapse. Cancer Res 1992; 52: 5110–4
  • Boucher Y, Kirkwood J M, Opacic D, Desantis M, Jain R K. Interstitial hypertension in superficial metastatic melanomas in humans. Cancer Res 1991; 51: 6691–4
  • Roh H D, Boucher Y, Kalnicki S, Buchsbaum R, Bloomer W D, Jain R K. Interstitial hypertension in carcinoma of uterine cervix in patients: possible correlaton with tumor oxygenation and radiation response. Cancer Res 1991; 51: 6695–8
  • Gutmann R, Leunig M, Feyh J, Goetz A F, Messmer E, Jain R K. Interstitial hypertension in head and neck tumors in patients: correlation with tumor size. Cancer Res 1992; 52: 1993–5
  • Less J R, Posner M C, Boucher Y, Borochovitz D, Wolmark N, Jain R K. Interstitial hypertension in human breast and colorectal tumors. Cancer Res 1992; 52: 6371–4
  • Curti B D, Urba W J, Alvord W J, et al. Interstitial pressure of subcutaneous nodules in melanoma and lymphoma patients: changes during treatment. Cancer Res 1993; 53: 2204–7
  • Taginawa N, Kanazawa T, Satomura K, et al. Experimental study on lymphatic vascular changes in the development of cancer. Lymphology 1981; 14: 149–54
  • Gerlowski L E, Jain R K. Microvascular permeability of normal and neoplastic tissues. Microvasc Res 1986; 31: 288–305
  • Sevick E M, Jain R K. Measurement of capillary filtration coefficient in a solid tumor. Cancer Res 1991; 51: 1352–5
  • Sevick E M, Jain R K. Viscous resistance to blood flow in solid tumors: effect of hematocrit on intratumor blood viscosity. Cancer Res 1989; 49: 3513–9
  • Sevick E M, Jain R K. Geometric resistance to blood flow in solid tumors perfused ex vivo: effects of tumor size and perfusion pressure. Cancer Res 1989; 49: 3506–12
  • Jain R K, Baxter L T. Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: significance of elevated interstitial pressure. Cancer Res 1988; 48: 7022–32
  • Jain R K. Transport of molecules in the tumor interstitium: a review. Cancer Res 1987; 47: 3039–51
  • Cobb L M. Intratumour factors influencing the access of antibody to tumour cells. Cancer Immunol Immunother 1989; 28: 235–40
  • Rofstad E K. Orthotopic human melanoma xenograft model systems for studies of tumour angiogenesis, pathophysiology, treatment sensitivity and metastatic pattern. Br J Cancer 1994; 70: 804–12
  • Fadnes H O, Reed R K, Aukland K. Interstitial fluid pressure in rats measured with a modified wick technique. Microvasc Res 1977; 14: 27–36
  • Zlotecki R A, Boucher Y, Lee I, Baxter L T, Jain R K. Effect of angiotensin II induced hypertension on tumor blood flow and interstitial fluid pressure. Cancer Res 1993; 53: 2466–8

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.