Interaction of the Antiemetics Ondansetron and Granisetron with the Cytotoxicity Induced by Irradiation, Epirubicin, Bleomycin, Estramustine, and Cisplatin in Vitro

References

• Sanger G J. New antiemetic drugs. J Physiol Pharmacol 1990; 68: 314–24
   Google Scholar
• Osborne R J, Slevin M L, Hunter R W, Hamer J. Cardiac arrhythmias during cytotoxic chemotherapy. Human Toxicol 1985; 4: 617–26
   PubMedGoogle Scholar
• Osieka R, Glatte P, Pannenbäcker R, Schmidt C G. Enhancement of semustine‐induced cytotoxicity by chlorpromazine and caffeine in a human melanoma xenograft. Cancer Treatm Rep 1986; 70: 1167–71
   PubMedGoogle Scholar
• Henriksson R, Grankvist K. Epirubicin cytotoxicity but not oxygen radical formation is enhanced by four different antiemetics. Med Oncol Tumor Pharmacother 1988; 6: 175–8
   Google Scholar
• Behnam Mothlagh P, Henriksson R, Grankvist K. Metoclopramide inhibits the cytotoxicity of cisplatin and enhances the cytotoxicity of epirubicin. Pharmacol Toxicol 1995; 76: 146–8
   PubMedGoogle Scholar
• Kjellen E, Wennerberg J, Pero R. Metoclopramide enhances the effect of cisplatin on xenografted squamous cell carcinoma of the head and neck. Br J Cancer 1989; 59: 247–50
   PubMed Web of Science ®Google Scholar
• Lybak S, Kjellen E, Wennerberg J, Pero R. Metoclopramide enhances the effect of ionising radiation on xenografted squamous cell carcinoma of the head and neck. Int J Radiat Oncol Biol Phys 1990; 19: 1419–24
   PubMed Web of Science ®Google Scholar
• Henriksson R, Lomberg H, Israelsson G, Zackrisson B, Franzén L. The effect of ondansetron on radiation‐induced emesis and diarrhoea. Acta Oncol 1992; 31: 767–9
   PubMed Web of Science ®Google Scholar
• Cole S P C. Rapid chemosensitivity testing of human lung tumor cells using the MTT assay. Cancer Chemother Pharmacol 1986; 17: 259–63
   PubMed Web of Science ®Google Scholar
• Henriksson R, Grankvist K. Interaction between anticancer drugs and after clinically used pharmaceuticals. Acta Oncol 1989; 28: 451–62
   PubMed Web of Science ®Google Scholar
• Andrews P L R, Davis C J, Bingham S, Davidson H I M, Hawthorn J. The abdominal visceral innervation and the emetic reflex. Pathways, pharmacology, and plasticity. Can J Physiol Pharmacol 1990; 68: 325–45
   PubMed Web of Science ®Google Scholar
• Hawthorn J, Ostler K J, Andrews P L R. The role of the abdominal visceral innervation on 5–hydroxytryptamine M‐re‐ceptor vomiting induced by cytotoxic drugs cyclophos‐phamide and cisplatin in the ferret. Q J Exp Physiol 1988; 73: 7–21
   PubMed Web of Science ®Google Scholar
• Higgins G A, Kilpatrick G J, Bunce K T, Jones B J, Tyers M B. 5–HT3 receptor antagonists injected into the area postrema inhibit cisplatin‐induced emesis in the ferret. Br J Pharmacol 1989; 97: 247–55
   PubMed Web of Science ®Google Scholar
• Greg L P, Goa K L. Granisetron. Drug Eval 1991; 42: 805–24
   Google Scholar
• Hall T J, James P R, Cambridge G. Development of an in vitro hepatotoxicity assay for assessing the effects of chronic drug exposure. Res Commun Chem Pathol Pharmacol 1993; 79: 249–56
   PubMedGoogle Scholar
• Blackwell C P, Harding S M. The clinical pharmacology of ondansetron. Eur J Clin Oncol 1989; 25(Suppl 1)S21–4
   PubMedGoogle Scholar
• Lybak S, Pero R. The benzamide derivative metoclopramide causes DNA damage and inhibition of DNA repair in human peripheral mononuclear leukocytes at clinically relevant doses. Carcinogenesis 1991; 12: 1613–7
   PubMed Web of Science ®Google Scholar
• Gralla R J. Metoclopramide. Drugs 1983, Suppl. 1: 63–73
   PubMedGoogle Scholar
• Catino J J, Francher D M, Schuring J E. Evaluation of cisdi‐amminedichloroplatinum(II) combined with metoclopramide or sodium thiosulphate on L1210 leukaemia in vitro and in vivo. Cancer Chemother Pharmacol 1986; 18: 1–4
   PubMedGoogle Scholar
• Tyson F L, Brown Y M, Walker D M, Belinsky S A, Anderson M W. Inhibition of murine pulmonary metastases by cis‐platinum in combination with metoclopramide. Proc Annu Meet Am Assoc Cancer Res 1990; 31: A2302
   Google Scholar
• Myers C. Anthracyclines. Cancer chemotheraphy, H Pinedo, B A Chabner. Elsevier Sci. Publ. 1986; 8: 52–64
   Google Scholar
• Grankvist K, Henriksson R. Doxorubicin and epirubicin ironinduced generation of free radicals in vitro ‐ a comparative study. Biosci Rep 1987; 7: 653–8
   PubMed Web of Science ®Google Scholar
• Torii Y, Saito H, Matsuki N. Induction of emesis in Suncus murinus by pyrogallol, a generator of free radicals. Br J Pharmacol 1994; 111: 431–4
   PubMed Web of Science ®Google Scholar
• Scarantino C W, Ornitz R D, Hoffman L G, Anderson R F, Jr. Radiation‐induced emesis: effects of ondansetron. Semin Oncol 1992; 16(Suppl 15)38–43
   Google Scholar