403
Views
69
CrossRef citations to date
0
Altmetric
Original Article

Induction of Apoptosis in Neuroendocrine Tumors of the Digestive System During Treatment with Somatostatin Analogs

, , , , , & show all
Pages 607-614 | Received 15 Jan 1997, Accepted 03 Jul 1997, Published online: 08 Jul 2009

References

  • Wilander E, Lundqvist M, Oberg K. Gastrointestinal carcinoid tumours. Histogenetic, histochemical, immunohistochemical, clinical and therapeutic aspects. Prog Histochem Cytochem 1989; 19: 1–88
  • Welbourn RB. Apudomas of the gut. Am J Surg 1977; 133: 13–22
  • Moertel CG. Treatment of carcinoid tumor and malignant carcinoid syndrom. J Clin Oncol. 1983; 1: 727–40
  • Kvols L K, Buck M. Chemotherapy of metastatic carcinoid and islet cell tumors. A review. Am J Med 1987; 82: 77–83
  • Öberg K, Eriksson B. Medical treatment of neuroendocrine gut and pancreatic tumors. Acta Oncol 1989; 28: 425–31
  • Oberg K, Funa K, Alm G. Effects of leukocyte interferon on clinical symptoms and hormone levels in patients with midgut carcinoid tumors and carcinoid syndrome. N Engl J Med 1983; 309: 129–33
  • Tiensuu Janson E M, Ahlstrom H, Anderson T, Öberg K E. Octreotide and interferon alfa: a new combination for the treatment of malignant carcinoid tumours. Eur J Cancer 1992; 28A: 1647–50
  • Kerr J FR, Wyllie A H, Currie AR. Apoptosis: a basic biological phenomenon with wide ranging implications in tissue kinetics. Brit J Cancer 1972; 26: 239–57
  • Wyllie A H, Kerr J F, Currie AR. Cell death: the significance of apoptosis. Int Rev Cytol 1980; 68: 251–306
  • Korsmeyer SJ. Programmed cell death: Bcl-2. Important advances in oncology, V T DeVita, Jr, S Hellman, SA Rosenberg. JB Lippincott Company, Philadelphia 1993; 19–28
  • Hickman JA. Apoptosis induced by anticancer drugs. Cancer Metastasis Rev 1992; 11: 121–39
  • Evers B M, Ishizuka J, Townsend C MJ, Thompson JC. The human carcinoid cell line, BON. A model system for the study of carcinoid tumors. Ann N Y Acad Sci 1994; 733: 393–406
  • Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992; 119: 493–501
  • Smith R E, Farquhar MG. Lysosome function in the regulation of the secretory process in cells of the anterior pituitary gland. J Cell Biol. 1966; 31: 319–47
  • Anderson T, Wilander E, Eriksson B, Lindgren P G, Oberg K. Effects of interferon on tumor tissue content in liver metastases of human carcinoid tumors. Cancer Res 1990; 50: 3413–5
  • Szende B, Schally A V, Comaru-Schally A M, . Cellular and molecular aspects of apoptosis in experimental tumors of animals treated with analogs of LHRH, somatostatin. Apoptosis: The molecular basis of cell death, L David Tomei, OC Frederick, et al. Cold Spring Harbor Laboratory Press, New York 1991; 139–55
  • Reubi J C, Schaer J C, Waser B, Mengod G. Expression and localization of somatostatin receptor SSTR1, SSTR2, and SSTR3 messenger RNAs in primary human tumors using in situ hybridization. Cancer Res 1994; 54: 3455–9
  • Kubota A, Yamada Y, Kagimoto S, et al. Identification of somatostatin receptor subtypes and an implication for the efficacy of somatostatin analogue SMS 201–995 in treatment of human endocrine tumors. J Clin Invest 1994; 93: 1321–5
  • Buscail L, Esteve J P, Saint-Laurent N, et al. Inhibition of cell proliferation by the somatostatin analogue RC-160 is mediated by somatostatin receptor subtypes SSTR2 and SSTR5 through different mechanisms. Proc Natl Acad Sci USA 1995; 92: 1580–4
  • Lamberts S W, van der Lely A J, de Herder W W, Hofland LJ. Octreotide. N Engl J Med (UNITED STATES) 1996; 334: 246–54
  • Evers B M, Hurlbut S C, Tyring S K, Townsend C MJ, Uchida T, Thompson JC. Novel therapy for the treatment of human carcinoid. Ann Surg 1991; 213: 411–6
  • Bursch W, Kleine L, Tenniswood M. The biochemistry of cell death by apoptosis. Biochem Cell Biol 1990; 68: 1071–4
  • Tormanen U, Eerola A K, Rainio P, et al. Enhanced apoptosis predicts shortened survival in non-small cell lung carcinoma. Cancer Res 1995; 55: 5595–602
  • Lipponen P K, Aaltomaa S. Apoptosis in bladder cancer as related to standard prognostic factors and prognosis. J Pathol 1994; 173: 333–9
  • Tatebe S, Ishida M, Kasagi N, Tsujitani S, Kaibara N, Ito H. Apoptosis occurs more frequently in metastatic foci than in primary lesions of human colorectal carcinomas: analysis by terminal-deoxynucleotidyl-transferase-mediated dUTP-biotin nick end labeling. Int J Cancer 1996; 65: 173–7
  • Lowe S W, Schmitt E M, Smith S W, Osborne B A, Jacks T. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 1993; 362: 847–9
  • Creasey A A, Bartholomew J C, Merigan TC. Role of G0-G1 arrest in the inhibition of tumor cell growth by interferon. Proc Natl Acad Sci USA 1980; 77: 1471–5
  • Panayiotidis P, Ganeshaguru K, Jabbar S A, Hoffbrand AV. Alpha-interferon (alpha-IFN) protects B-chronic lymphocytic leukaemia cells from apoptotic cell death in vitro. Br J Haematol 1994; 86: 169–73
  • Vedantham S, Gamliel H, Golomb HM. Mechanism of interferon action in hairy cell leukemia: a model of effective cancer biotherapy. Cancer Res 1992; 52: 1056–66
  • Ezekowitz R A, Mulliken J B, Folkman J. Interferon alfa-2a therapy for life-threatening hemangiomas of infancy. N Engl J Med 1992; 326: 1456–63

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.