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Research Article

Hypofractionated Adjuvant Whole Breast Radiotherapy: Progress and Prospects

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Pages 1288-1292 | Received 20 May 2010, Accepted 15 Jul 2010, Published online: 18 Oct 2010

References

  • Williams MV, Denekamp J, Fowler JF. A review of alpha/beta ratios for experimental tumors: implications for clinical studies of altered fractionation. Int J Radiat Oncol Biol Phys. 1985 Jan;11(1):87–96.
  • Thames HD, Bentzen SM, Turesson I, Overgaard M, van den Bogaert W. Fractionation parameters for human tissues and tumors. Int J Radiat Biol. 1989 Nov;56(5):701–10.
  • Douglas BG. Superfractionation: its rationale and anticipated benefits. Int J Radiat Oncol Biol Phys. 1982 Jul; 8(7):1143–53.
  • Miles EF, Lee WR. Hypofractionation for prostate cancer: a critical review. Semin Radiat Oncol. 2008 Jan;18(1):41–7.
  • Withers HR, Thames HD, Jr., Peters LJ. A new isoeffect curve for change in dose per fraction. Radiother Oncol. 1983 Nov;1(2):187–91.
  • Fowler JF. The linear-quadratic formula and progress in fractionated radiotherapy. Br J Radiol. 1989 Aug;62(740): 679–94.
  • Bates TD. The 10-year results of a prospective trial of post-operative radiotherapy delivered in 3 fractions per week versus 2 fractions per week in breast carcinoma. Br J Radiol. 1988 Jul;61(727):625–30.
  • Overgaard M, Bentzen SM, Christensen JJ, Madsen EH. The value of the NSD formula in equation of acute and late radiation complications in normal tissue following 2 and 5 fractions per week in breast cancer patients treated with postmastectomy irradiation. Radiother Oncol. 1987 May;9(1):1–11.
  • Whelan T, MacKenzie R, Julian J, Levine M, Shelley W, Grimard L, . Randomized trial of breast irradiation schedules after lumpectomy for women with lymph node-negative breast cancer. J Natl Cancer Inst. 2002 Aug 7;94(15):1143–50.
  • Yarnold J, Ashton A, Bliss J, Homewood J, Harper C, Hanson J, . Fractionation sensitivity and dose response of late adverse effects in the breast after radiotherapy for early breast cancer: long-term results of a randomised trial. Radiother Oncol. 2005 Apr;75(1):9–17.
  • Owen JR, Ashton A, Bliss JM, Homewood J, Harper C, Hanson J, . Effect of radiotherapy fraction size on tumour control in patients with early-stage breast cancer after local tumour excision: long-term results of a randomised trial. Lancet Oncol. 2006 Jun;7(6):467–71.
  • Bentzen SM, Agrawal RK, Aird EG, Barrett JM, Barrett-Lee PJ, Bliss JM, . The UK Standardisation of Breast Radiotherapy (START) Trial A of radiotherapy hypofractionation for treatment of early breast cancer: a randomised trial. Lancet Oncol. 2008 Apr;9(4):331–41.
  • Bentzen SM, Agrawal RK, Aird EG, Barrett JM, Barrett-Lee PJ, Bliss JM, . The UK Standardisation of Breast Radiotherapy (START) Trial B of radiotherapy hypofractionation for treatment of early breast cancer: a randomised trial. Lancet. 2008 Mar 29;371(9618):1098–107.
  • James ML, Lehman M, Hider PN, Jeffery M, Francis DP, JHickey BE. Fraction size for radiation treatment for breast conservation in early breast cancer. Cochrane Database of Systematic Reviews. 2008(3).
  • Whelan TJ, Pignol JP, Levine MN, Julian JA, Mackenzie R, Parpia S, . Long-Term Results of Hypofractionated Radiation Therapy for Breast Cancer. N Engl J Med. 2010 Feb 11;362(6):513–20.
  • Bartelink H, Arriagada R. Hypofractionation in radiotherapy for breast cancer. Lancet. 2008 Mar 29;371(9618):1050–2.
  • Bartelink H, Horiot JC, Poortmans PM, Struikmans H, Van den Bogaert W, Fourquet A, . Impact of a higher radiation dose on local control and survival in breast- conserving therapy of early breast cancer: 10-year results of the randomized boost versus no boost EORTC 22881–10882 trial. J Clin Oncol. 2007 Aug 1;25(22):3259–65.
  • Gagliardi G, Constine LS, Moiseenko V, Correa C, Pierce LJ, Allen AM, . Radiation dose-volume effects in the heart. Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3 Suppl): S77–85.
  • Mannino M, Yarnold JR. Local relapse rates are falling after breast conserving surgery and systemic therapy for early breast cancer: Can radiotherapy ever be safely withheld? Radiother Oncol. 2009 Jan;90(1):14–22.
  • Borger J, Kemperman H, Hart A, Peterse H, van Dongen J, Bartelink H. Risk factors in breast-conservation therapy. J Clin Oncol. 1994 Apr;12(4):653–60.
  • Vrieling C, Collette L, Fourquet A, Hoogenraad WJ, Horiot JH, Jager JJ, . The influence of patient, tumor and treatment factors on the cosmetic results after breast-conserving therapy in the EORTC ‘boost vs. no boost’ trial. EORTC Radiotherapy and Breast Cancer Cooperative Groups. Radiother Oncol. 2000 Jun;55(3):219–32.
  • Courdi A, Ortholan C, Hannoun-Levi JM, Ferrero JM, Largillier R, Balu-Maestro C, . Long-term results of hypofractionated radiotherapy and hormonal therapy without surgery for breast cancer in elderly patients. Radiother Oncol. 2006 May;79(2):156–61.
  • Kirova YM, Campana F, Savignoni A, Laki F, Muresan M, Dendale R, . Breast-conserving treatment in the elderly: long-term results of adjuvant hypofractionated and normofractionated radiotherapy. Int J Radiat Oncol Biol Phys. 2009 Sep 1;75(1):76–81.
  • Brunt AM, Sydenham M, Bliss J, Coles CE, Gothard L, Harnett A, . A 5-fraction regimen of adjuvant radiotherapy for women with early breast cancer: first analysis of the randomised UK FAST trial (ISRCTN62488883, CRUKE/04/015). EJC Supplements Presidential sessions late breaking and best of ECCO 15-ESMO 34 Abstracts. 2009 20–24 September 2009;7(3):2.

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